发明申请
WO2016074794A1 DERMAL FILLER BASED ON CROSSLINKED HYALURONIC ACID AND CARBOXYMETHYL CELLULOSE LUBRICANT
审中-公开
基于交联羟丙酸和羧甲基纤维素润滑剂的真空填料
- 专利标题: DERMAL FILLER BASED ON CROSSLINKED HYALURONIC ACID AND CARBOXYMETHYL CELLULOSE LUBRICANT
- 专利标题(中): 基于交联羟丙酸和羧甲基纤维素润滑剂的真空填料
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申请号: PCT/EP2015/002270申请日: 2015-11-12
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公开(公告)号: WO2016074794A1公开(公告)日: 2016-05-19
- 发明人: HAGEDORN, Nadine , STRAGIES, Roland , VILLAIN, Franck
- 申请人: MERZ PHARMA GMBH & CO. KGAA
- 申请人地址: Eckenheimer Landstraße 100 60318 Frankfurt am Main DE
- 专利权人: MERZ PHARMA GMBH & CO. KGAA
- 当前专利权人: MERZ PHARMA GMBH & CO. KGAA
- 当前专利权人地址: Eckenheimer Landstraße 100 60318 Frankfurt am Main DE
- 代理机构: RICKER, Mathias
- 优先权: EP14003829.0 20141113; EP15000338.2 20150205
- 主分类号: A61L27/20
- IPC分类号: A61L27/20 ; A61L27/26 ; A61L27/52
摘要:
The present invention relates to injectable dermal filler compositions in the form of a gel, comprising hyaluronic acid (HA), carboxymethyl cellulose (CMC) and, optionally, microparticles such as calcium hydroxyapatite (CaHAP) microparticles. The injectable dermal filler compositions have improved rheological properties while at the same time have low extrusion forces. The present invention further relates to a method for preparing such injectable dermal filler compositions and their use for cosmetic and therapeutic purposes.