Invention Application
WO2016161090A1 RESPIRATION DEVICE FOR ANALYSIS OF A RESPONSE TO SHEAR STRESS AND FOREIGN AGENTS ON CELLS
审中-公开
用于分析剪切应力和外源细胞的响应的呼吸装置
- Patent Title: RESPIRATION DEVICE FOR ANALYSIS OF A RESPONSE TO SHEAR STRESS AND FOREIGN AGENTS ON CELLS
- Patent Title (中): 用于分析剪切应力和外源细胞的响应的呼吸装置
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Application No.: PCT/US2016/025228Application Date: 2016-03-31
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Publication No.: WO2016161090A1Publication Date: 2016-10-06
- Inventor: HAJIPOURAN BENAM, Kambez , NOVAK, Richard , SLIZ, Josiah , FERRANTE, Thomas, Charles , INGBER, Donald, Elliot , CHOE, Youngjae
- Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Applicant Address: 17 Quincy Street Cambridge, Massachusetts 02138 US
- Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee Address: 17 Quincy Street Cambridge, Massachusetts 02138 US
- Agency: RESNICK, David, S. et al.
- Priority: US62/141,560 20150401
- Main IPC: C12N5/02
- IPC: C12N5/02 ; C12N5/22 ; C12M1/16 ; C12M3/04 ; G01N33/53
Abstract:
A microfluidic system for determining a response of cells comprises one or more fluid pumps. The one or more fluid pumps move a fluid across cells within a microfluidic device. The microfluidic device includes a microchannel at least partially defined by a surface having cells adhered thereto, a first port at one end of the microchannel, and a second port at an opposing end of the microchannel. The one or more fluid pumps move the fluid across the cells in a first direction toward the second port and then move the fluid across the cells in a second direction toward the first port.
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