- 专利标题： A METHOD TO GENERATE CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELLS (CAR-T CELLS) FROM PATHOGEN-SPECIFIC CYTOTOXIC LYMPHOCYTES TO ENABLE THE SUBSEQUENT IN VIVO MODULATION OF THEIR FUNCTIONAL ACTIVITY
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申请号： PCT/US2021/021411申请日： 2021-03-08
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公开(公告)号： WO2021178975A1公开(公告)日： 2021-09-10
- 发明人: GOLDSTEIN, Harris , ALMO, Steven C. , GARFORTH, Scott , LI, Mengyan
- 申请人： ALBERT EINSTEIN COLLEGE OF MEDICINE
- 申请人地址： 1300 Morris Park Avenue
- 专利权人： ALBERT EINSTEIN COLLEGE OF MEDICINE
- 当前专利权人： ALBERT EINSTEIN COLLEGE OF MEDICINE
- 当前专利权人地址： 1300 Morris Park Avenue
- 代理机构： MORRIS, Patrick D. et al.
- 优先权： US62/986,572 2020-03-06
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; A61K35/76 ; A61K35/761 ; A61K38/16 ; A61K39/00 ; A61K39/002
摘要：
The present disclosure relates to a method of modulating one or more genetically modified cells, e.g., chimeric antigen receptor (CAR)-expressing cells, ex vivo and/or in vivo.
