- 专利标题: PASSIVE SOLVENT MIXER FOR LIQUID CHROMATOGRAPHY
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申请号: PCT/US2022/030670申请日: 2022-05-24
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公开(公告)号: WO2022271382A1公开(公告)日: 2022-12-29
- 发明人: GRITTI, Fabrice
- 申请人: WATERS TECHNOLOGIES CORPORATION
- 申请人地址: 34 Maple Street
- 专利权人: WATERS TECHNOLOGIES CORPORATION
- 当前专利权人: WATERS TECHNOLOGIES CORPORATION
- 当前专利权人地址: 34 Maple Street
- 代理机构: GUERIN, William G.
- 优先权: US63/213,890 2021-06-23
- 主分类号: B01F33/30
- IPC分类号: B01F33/30 ; B01F25/432 ; B01F25/433 ; B01F2101/2204 ; B01F25/4323 ; B01F25/4331 ; G01N2030/027 ; G01N2030/347 ; G01N30/02 ; G01N30/34
摘要:
Described is a mixer for a liquid chromatography system. The mixer (58) includes an inlet (42), an outlet (50), a first flow channel (44B), and a second flow channel (44A). The inlet receives a fluid flow to be mixed and the outlet provides the mixed fluid flow. Each of the two flow channels is coupled between the inlet and the outlet. The second flow channel includes an offset volume that delays fluid propagation through the second flow channel relative to the first flow channel. The offset volume includes a coiled channel (64) which increases radial dispersion and decreases axial dispersion of a fluid flowing through the offset volume, thereby enabling a further reduction in periodic noise in a detector baseline signal as compared to known split flow mixers for liquid chromatography systems.