PASSIVE SOLVENT MIXER FOR LIQUID CHROMATOGRAPHY
摘要:
Described is a mixer for a liquid chromatography system. The mixer (58) includes an inlet (42), an outlet (50), a first flow channel (44B), and a second flow channel (44A). The inlet receives a fluid flow to be mixed and the outlet provides the mixed fluid flow. Each of the two flow channels is coupled between the inlet and the outlet. The second flow channel includes an offset volume that delays fluid propagation through the second flow channel relative to the first flow channel. The offset volume includes a coiled channel (64) which increases radial dispersion and decreases axial dispersion of a fluid flowing through the offset volume, thereby enabling a further reduction in periodic noise in a detector baseline signal as compared to known split flow mixers for liquid chromatography systems.
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