Invention Application
- Patent Title: UTILIZATION OF ANTIBODIES TO SHAPE ANTIBODY RESPONSES TO AN ANTIGEN
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Application No.: PCT/US2022/035968Application Date: 2022-07-01
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Publication No.: WO2023283134A1Publication Date: 2023-01-12
- Inventor: MURPHY, Andrew , KYRATSOUS, Christos , BAUM, Alina , PETRO, Christopher
- Applicant: REGENERON PHARMACEUTICALS, INC.
- Applicant Address: 777 Old Saw Mill River Road
- Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee Address: 777 Old Saw Mill River Road
- Agency: CHEN, Hongfan et al.
- Priority: US63/218,486 2021-07-05
- Main IPC: C07K16/10
- IPC: C07K16/10 ; A61K39/215 ; A61P31/14
Abstract:
Described herein are methods and compositions for directing an antibody response in a subject away from one or more first epitopes of an antigen (e.g., immunodominant epitopes of a vaccine antigen) and towards one or more second epitopes of the antigen by administering one or more antibodies targeting the one or more first epitopes of the antigen.
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