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公开(公告)号：WO2023283134A1
公开(公告)日：2023-01-12
申请号：PCT/US2022/035968
申请日：2022-07-01
Applicant: REGENERON PHARMACEUTICALS, INC.
Inventor： MURPHY, Andrew , KYRATSOUS, Christos , BAUM, Alina , PETRO, Christopher
IPC: C07K16/10 , A61K39/215 , A61P31/14
Abstract: Described herein are methods and compositions for directing an antibody response in a subject away from one or more first epitopes of an antigen (e.g., immunodominant epitopes of a vaccine antigen) and towards one or more second epitopes of the antigen by administering one or more antibodies targeting the one or more first epitopes of the antigen.
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