公开(公告)号：EP0698039A1

公开(公告)日：1996-02-28

申请号：EP94916812.0

申请日：1994-05-18

申请人： RESEARCH CORPORATION TECHNOLOGIES ,  BROXMEYER, Hal E. ,  COOPER, Scott ,  LU, Li

发明人： BROXMEYER, Hal E. ,  COOPER, Scott ,  LU, Li ,  MOORE, Robert N. ,  KREISBERG, Robert ,  KREISBERG, Melinda Detrick

IPC分类号： A61K38 ,  A61P7 ,  A61P9 ,  C07K7 ,  C07K14

CPC分类号： C07K7/08 ,  A61K38/00 ,  C07K14/4703

摘要： Peptides containing the sequence Ala-Lys-Pro-Arg have suppressive effects on the proliferation of a broad range of myelopoietic progenitor cells. In a preferred embodiment, the peptide has the sequence Glu-Thr-Val-Ile-Met-Lys-Ala-Lys-Pro-Arg-Ala-Asn-Phe-Pro. The peptides of the present invention are useful in the treatment of myelopoietic hyperproliferative disorders, and in protecting myeloid cells from damage induced by chemotherapy and radiation. Peptides containing the sequence Ala-Lys-Pro-Arg are also useful in the treatment of endotoxin-induced septic shock.

公开(公告)号：EP3207968A1

公开(公告)日：2017-08-23

申请号：EP16159601.0

申请日：2016-03-10

申请人： Knecht, Jr., William ,  Cooper, Scott

发明人： Knecht, Jr., William ,  Cooper, Scott

IPC分类号： A63F13/795 ,  A63F13/332 ,  A63F13/44 ,  H04M1/725 ,  H04N21/43 ,  H04N21/4788

CPC分类号： H04N21/4788 ,  A63F13/332 ,  A63F13/44 ,  A63F13/795 ,  H04M1/72544 ,  H04N21/4307 ,  H04N21/4758

摘要： A computer implemented method and system for playing a real time synchronized pooled interactive trivia game which allows users to socialize while experiencing the watching of licensed media content be more social, competitive and interactive is disclosed. The method and system comprises of a web server that communicates between a user profile database and client devices via an interconnecting computer network, wherein a scheduling server establishes upon a user's request a schedule and participant list, wherein a media database for storing licensed media content communicates with a media server for providing the media content to the users and a gaming server in communication with the media server for providing parallel game play to the plurality of scheduled users simultaneously as they view the media content. The invention promotes a user to enjoy media content again and again, wherein each time the potential experience of watching the movie is different.

摘要翻译： 公开了一种用于播放实时同步的池式交互式琐事游戏的计算机实现的方法和系统，其允许用户在观看许可的媒体内容的同时进行社交，从而更具社交性，竞争性和交互性。 所述方法和系统包括网络服务器，所述网络服务器经由互连计算机网络在用户简档数据库和客户端设备之间进行通信，其中，调度服务器根据用户的请求建立时间表和参与者列表，其中用于存储许可的媒体内容的媒体数据库 具有用于向用户提供媒体内容的媒体服务器和与媒体服务器通信的游戏服务器，用于在多个被调度用户观看媒体内容的同时向多个被调度用户同时提供并行游戏。 本发明促使用户一次又一次地欣赏媒体内容，其中每次观看电影的潜在体验都不相同。