3-HYDROXYANTHRANILIC ACID (3-HAA) THERAPY FOR PREVENTION AND TREATMENT OF HYPERLIPIDEMIA AND ITS CARDIOVASCULAR COMPLICATIONS
    3.
    发明公开
    3-HYDROXYANTHRANILIC ACID (3-HAA) THERAPY FOR PREVENTION AND TREATMENT OF HYPERLIPIDEMIA AND ITS CARDIOVASCULAR COMPLICATIONS 有权
    疗法-3-羟基-2-氨基(3- HAA)心血管并发症及其高脂血症的预防和治疗

    公开(公告)号:EP2736505A1

    公开(公告)日:2014-06-04

    申请号:EP12820828.7

    申请日:2012-07-13

    发明人: KETELHUTH, Daniel

    IPC分类号: A61K31/196 A61P3/06

    CPC分类号: A61K31/196

    摘要: The present invention relates to the use of a tryptophan metabolite, 3- hydroxyanthranilic acid (3-HAA)or a functional analogue thereof, for prophylactic and/or therapeutic treatment of mammals, in special humans, against hyperlipidemia and its cardiovascular complications, i.e atheroma formation, myocardial infarction and heart failure, ischemic stroke and transient ischemic attacks, renal impairment, aortic aneurysms and critical limb ischemia caused by atherosclerosis.

    摘要翻译: 本发明涉及使用色氨酸代谢物,3-羟基邻氨基苯甲酸(3-HAA)或其功能类似物的,其用于哺乳动物的预防和/或治疗性治疗,在特殊人类,对高脂血症和其心血管并发症,即 动脉粥样硬化形成,心肌梗死和心脏衰竭,缺血性卒中和短暂性脑缺血发作,肾功能不全,主动脉瘤和动脉粥样硬化引起的严重肢体缺血。