专利检索 ap:"Shangai Institute of Materia Medica, Chinese Academy of Sciences" 第 1 页

1.

发明授权
TETRAHYDROPROTOBERBERINE COMPOUNDS, THE SYNTHETIC METHOD AND THE USE THEREOF 有权
标题翻译：四氢罗哌卡因化合物，合成方法及其用途

公开(公告)号：EP1904493B1

公开(公告)日：2013-03-27

申请号：EP06753117.8

申请日：2006-07-07

申请人： Shangai Institute of Materia Medica, Chinese Academy of Sciences , Topharman Shanghai Co., Ltd.

发明人： LI, Jianfeng , LIU, Aixiang , CHEN, Xinjian , JIN, Guozhang , YAN, Tiema , ZHANG, Rongxia , ZHU, Yi , PAN, Yanjun , SHEN, Jingshan , SHEN, Jingkang

IPC分类号： C07D455/03 , A61K31/4375 , A61P25/00 , A61P25/06 , A61P25/16 , A61P25/18

CPC分类号： C07D455/03

2.

发明公开
TETRAHYDROPROTOBERBERINE COMPOUNDS, THE SYNTHETIC METHOD AND THE USE THEREOF 有权
标题翻译：四氢罗哌卡因化合物，合成方法及其用途

公开(公告)号：EP1904493A1

公开(公告)日：2008-04-02

申请号：EP06753117.8

申请日：2006-07-07

申请人： Shangai Institute of Materia Medica, Chinese Academy of Sciences , Topharman Shanghai Co., Ltd.

发明人： LI, Jianfeng , LIU, Aixiang , CHEN, Xinjian , JIN, Guozhang , YAN, Tiema , ZHANG, Rongxia , ZHU, Yi , PAN, Yanjun , SHEN, Jingshan , SHEN, Jingkang

IPC分类号： C07D455/03 , A61K31/4375 , A61P25/00 , A61P25/18

CPC分类号： C07D455/03

摘要： The present invention relates to tetraliydroprotoberberines of the formula (I) and the physiologically acceptable salts thereof. The invention also relates to the use of the compounds of the formula (I) or pharmaceutically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of a medical disorder susceptible to treatment with dopamine receptor ligand, such as schizophrenia.

摘要翻译： 本发明涉及式（I）的四氢噻喃小檗碱及其生理上可接受的盐。本发明还涉及式（I）化合物或其药学上可接受的盐在制备用于治疗易受多巴胺受体配体如精神分裂症治疗的医学病症的药物组合物中的用途。

3.

发明公开
SINOMENINE AND SINOMENINE COMPOUNDS, SYNTHESIS AND USE 审中-公开
标题翻译：青藤和SINOMENINEVERBINDUNGEN，合成和应用

公开(公告)号：EP1565444A1

公开(公告)日：2005-08-24

申请号：EP03782481.0

申请日：2003-11-26

申请人： Shangai Institute of Materia Medica, Chinese Academy of Sciences

发明人： QIN, Guo-Wei , TANG, Xi-Can , WANG, Rui,Room 501, No1,Lane 1717 , ZHOU, Tian-Xi,Room 1208, No2,Lane 69 , LESTAGE, Pierre , CAIGNARD, Daniel-Henri , RENARD, Pierre

IPC分类号： C07D221/28 , C07D489/00 , A61K31/485

CPC分类号： C07D221/28

摘要： The invention relates to sinomenine and compounds thereof and also to compounds of formula (I), wherein R1 represents an alkyl group; R2 represents a hydrogen atom or an alkylcarbonyl group, an haloalkylcarbonyl group or an arylcarbonyl; Y represents a group (II), (III) or (IV); R3 ,R4, R’4, R5, R’5 and R6 are as defined in the description; and X represents a halogen atom. Medicaments.