公开(公告)号：EP1926731A2

公开(公告)日：2008-06-04

申请号：EP06803813.2

申请日：2006-09-19

申请人： ABBOTT LABORATORIES

发明人： SCHRIMPF, Michael, R. ,  SIPPY, Kevin, B. ,  ANDERSON, David, J. ,  BUNNELLE, William, H. ,  NERSESIAN, Diana, L.

IPC分类号： C07D471/18 ,  A61K31/435 ,  A61P25/00 ,  C07D487/04 ,  C07D487/08

CPC分类号： C07D487/04

摘要： The invention relates to amine-substituted aza-adamantane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. Radiolabelled compounds useful for evaluating the binding affinity to α7 nicotinic acetylcholine receptors also are described.