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1.MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME 有权
标题翻译: 多聚IL-15可溶性融合分子和方法的生产和使用公开(公告)号:EP2619229A4
公开(公告)日:2014-03-26
申请号:EP11827439
申请日:2011-09-21
发明人: WONG HING C , RHODE PETER , LIU BAI , ZHU XIAOYUN , HAN KAI-PING
IPC分类号: C07K19/00 , A61K38/00 , A61K38/17 , A61P35/00 , C07K14/075 , C07K14/54 , C07K14/715 , C12N1/00 , C12N5/00 , C12N15/62
CPC分类号: C07K14/7155 , A61K38/00 , A61K38/1793 , A61K38/2086 , A61K39/3955 , A61K45/06 , C07K14/5443 , C07K16/18 , C07K16/2887 , C07K2317/622 , C07K2317/732 , C07K2319/00 , C07K2319/21 , C07K2319/22 , C07K2319/30 , C12N15/09 , C12N15/62 , C12P21/00 , A61K2300/00
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公开(公告)号:EP3160498A4
公开(公告)日:2017-12-06
申请号:EP15815782
申请日:2015-06-30
发明人: LIU BAI , RHODE PETER , XU WENXIN , WONG HING C
IPC分类号: A61K39/00 , A61K39/385 , A61P35/00
CPC分类号: A61K38/2086 , A61K39/39558 , C07K14/5443 , C07K14/7155 , C07K16/2818 , C07K16/2827 , C07K16/2887 , C07K16/32 , C07K2317/732 , C07K2319/30 , A61K2300/00
摘要: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
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公开(公告)号:EP2411545A4
公开(公告)日:2012-09-05
申请号:EP10756833
申请日:2010-03-25
发明人: FERNANDEZ MARILYN , LIU BAI , MARCUS WARREN D , WONG HING C
IPC分类号: C12Q1/70
CPC分类号: C07K14/70503 , C07K14/705 , C07K14/7051 , G01N33/56988
摘要: The instant invention provides TCRs having one or more amino acid substitutions that bind to the AL9 epitope of the HIV protein vpr (AIIRILQQL (SEQ ID NO: 1)).
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