公开(公告)号：EP1828341A2

公开(公告)日：2007-09-05

申请号：EP05850800.3

申请日：2005-12-20

申请人： AMO Groningen B.V.

发明人： LIU, Yan ,  HILBORN, Jons, Gunnar ,  HAITJEMA, Hendrick, Jan ,  NORRBY, Sverker ,  TERWEE, Thom

IPC分类号： C09J183/12 ,  C08G18/61 ,  C08G77/458 ,  A61L27/14 ,  C08G77/46 ,  G02B1/04 ,  C08G77/452

CPC分类号： C08G18/61 ,  A61L24/046 ,  A61L27/34 ,  C08G18/72 ,  C08G71/04 ,  C08G77/452 ,  C08G77/458 ,  C08G77/46 ,  C09J183/12 ,  G02B1/043 ,  C08L83/04

摘要： The present invention relates to amphiphilic block copolymers comprising at least one block of hydrophilic units and at least one block of hydrophobic units, wherein at least one hydrophobic block contains siloxane units. The present invention may be particularly useful as a tissue adhesive or as a coating for an intraocular lens (IOL). As an IOL coating, copolymers according to the invention may be used, for example, to promote tissue adhesion for the prevention of posterior capsule opacification.

公开(公告)号：EP1828341B1

公开(公告)日：2010-10-06

申请号：EP05850800.3

申请日：2005-12-20

申请人： AMO Groningen B.V.

发明人： LIU, Yan ,  HILBORN, Jons, Gunnar ,  HAITJEMA, Hendrick, Jan ,  NORRBY, Sverker ,  TERWEE, Thom

IPC分类号： C09J183/12 ,  C08G18/61 ,  C08G77/458 ,  A61L27/14 ,  C08G77/46 ,  G02B1/04 ,  C08G77/452

CPC分类号： C08G18/61 ,  A61L24/046 ,  A61L27/34 ,  C08G18/72 ,  C08G71/04 ,  C08G77/452 ,  C08G77/458 ,  C08G77/46 ,  C09J183/12 ,  G02B1/043 ,  C08L83/04

摘要： The present invention relates to amphiphilic block copolymers comprising at least one block of hydrophilic units and at least one block of hydrophobic units, wherein at least one hydrophobic block contains siloxane units. The present invention may be particularly useful as a tissue adhesive or as a coating for an intraocular lens (IOL). As an IOL coating, copolymers according to the invention may be used, for example, to promote tissue adhesion for the prevention of posterior capsule opacification.

公开(公告)号：EP1838758B1

公开(公告)日：2017-04-12

申请号：EP05854540.1

申请日：2005-12-16

申请人： AMO Groningen B.V.

发明人： LIU, Yan ,  HILBORN, Jons Gunnar ,  HAITJEMA, Hendrik Jan

IPC分类号： C08G77/18 ,  C08G77/20 ,  B29D11/00

CPC分类号： C08G77/16 ,  A61L27/18 ,  A61L2400/06 ,  A61L2430/16 ,  C08G77/20 ,  C08G77/38 ,  C08L67/04

公开(公告)号：EP1838758A1

公开(公告)日：2007-10-03

申请号：EP05854540.1

申请日：2005-12-16

申请人： AMO Groningen B.V.

发明人： LIU, Yan ,  HILBORN, Jons Gunnar ,  HAITJEMA, Hendrik Jan

IPC分类号： C08G77/18 ,  C08G77/20 ,  B29D11/00

CPC分类号： C08G77/16 ,  A61L27/18 ,  A61L2400/06 ,  A61L2430/16 ,  C08G77/20 ,  C08G77/38 ,  C08L67/04

摘要： A linear polysiloxane copolymer has at least one terminal hydroxyalkyl group. The copolymer is preparable by a process comprising a combination of a base-catalysed polymerisation with an acid-catalysed redistribution, and is suitable for preparing ophthalmic compositions for forming an intraocular lens in situ.

摘要翻译： 线性聚硅氧烷共聚物具有至少一个末端羟烷基。 共聚物可通过包含碱催化的聚合与酸催化再分配的组合的方法制备，并且适用于制备用于原位形成眼内透镜的眼用组合物。