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公开(公告)号：EP2783702B1
公开(公告)日：2018-11-14
申请号：EP12851320.7
申请日：2012-11-21
发明人： AH, Young Chang , CHO, Sung Yeon , HWANG, In Seok , PARK, Sun Young , KO, Hyun Ju , KIM, Hyuk , KWON, Min Jung , PARK, Won Seok
CPC分类号： C08L5/08 , A61K9/06 , A61K47/36 , A61L15/28 , A61L27/20 , A61L2400/06 , C08B37/0072
摘要： The invention, provides a method for preparing a water insoluble gel composition comprising: mixing a water soluble an epoxy cross-linking agent, an alkaline compound and a solvent; and drying the thus mixture at 1 to 30°C under vacuum to remove the solvent, and a water insoluble gel composition.
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公开(公告)号：EP3116523B1
公开(公告)日：2018-10-17
申请号：EP15712232.6
申请日：2015-03-10
申请人： 3-D Matrix, Ltd.
CPC分类号： A61L31/047 , A61B17/12104 , A61B17/12181 , A61B17/12186 , A61K38/07 , A61K49/006 , A61L31/028 , A61L31/14 , A61L31/145 , A61L31/16 , A61L2300/442 , A61L2400/06 , A61L2400/12 , A61L2430/36
摘要： Materials and methods for forming a bronchial obstruction are provided. A peptide comprising between about 7 amino acids and about 32 amino acids in a solution may be introduced to a target site. A hydrogel barrier may be provided at the target site in order to provide a bronchial obstruction.
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公开(公告)号：EP3377128A1
公开(公告)日：2018-09-26
申请号：EP16809547.9
申请日：2016-11-18
申请人： Car Holding B.V.
CPC分类号： A61L24/02 , A61L24/0089 , A61L24/046 , A61L31/06 , A61L31/128 , A61L31/18 , A61L2400/06 , A61L2430/36 , C08L83/04
摘要： The invention relates to a kit of parts suitable for preparing a cured biocompatible silicone polymer material including an X-ray contrast agent, the kit comprising two or more containers containing a fluid component, which components - when mixed - form a fluid curable biocompatible polymer composition, which upon curing forms the cured biocompatible silicone polymer material, wherein a first container contains a fluid component A, which component A comprises a curable silicone (pre-)polymer and a curing agent and which component A is essentially free of curing catalyst and metallic X-ray contrast agent particles, and a second container contains a fluid component B, which component B is a dispersion comprising metallic X-ray contrast agent particles and which is essentially free of curing agent.
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公开(公告)号：EP3373870A1
公开(公告)日：2018-09-19
申请号：EP16865154.5
申请日：2016-11-11
CPC分类号： A61L24/06 , A61B8/0833 , A61B8/0841 , A61B8/085 , A61B8/0891 , A61B8/481 , A61B8/488 , A61B17/12 , A61B17/12022 , A61B17/12186 , A61B17/3403 , A61B17/42 , A61B2017/3413 , A61F6/22 , A61K49/223 , A61K49/226 , A61L24/001 , A61L24/0015 , A61L24/0031 , A61L24/0036 , A61L27/52 , A61L27/54 , A61L2300/626 , A61L2400/06 , A61L2430/36
摘要： Disclosed are methods of delivering an agent to the lumen of the vas deferens under guidance of ultrasound imaging. The methods include vas-occlusive contraception in which the vas deferens is non-surgically isolated and an occlusive substance is percutaneously administered into the lumen of the vas deferens under ultrasound. Also disclosed are methods of reversal of vas-occlusive contraception and methods of delivering an agent to the lumen of the vas deferens. Also disclosed are compositions for use in the methods of the invention.
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公开(公告)号：EP3370793A2
公开(公告)日：2018-09-12
申请号：EP16810045.1
申请日：2016-11-02
发明人： FREY, Peter , HUBBELL, Jeffrey Alan , LUTOLF, Matthias , VARDAR, Elif , LARSSON, Hans Mattias , BALET, Eva-Maria , PINNAGODA, Kalitha , ALLAZETTA, Simone
IPC分类号： A61L27/48
CPC分类号： A61L27/48 , A61L2400/06 , A61L2430/34 , C08L89/06 , C08L89/00
摘要： The invention relates to a scaffold material comprising a carrier and embedded microbeads for use in tissue engineering applications such as soft tissues therapeutic treatment. The scaffold provides a short-term bulking effect coupled with a long-term functional activity. Both the carrier and the microbeads are substantially composed of natural or extracellular matrix-derived polymers, and the beads can comprise homogeneously distributed active agents, providing a regulated agent release along time. An aspect of the invention relates to a method for producing the microbeads of the invention by using an expressly designed microfluidic chip.
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公开(公告)号：EP2753647B1
公开(公告)日：2018-08-15
申请号：EP12772834.3
申请日：2012-09-06
申请人： ALLERGAN, INC.
CPC分类号： A61L27/24 , A61K8/042 , A61K8/65 , A61K8/735 , A61K2800/91 , A61L27/26 , A61L27/52 , A61L2400/06 , A61L2430/34 , A61Q19/08 , C08B37/0072 , C08H1/00 , C08L5/08 , C08L89/00 , H04R1/1066 , H04R1/1075 , C08L5/00 , C08L89/06
摘要： Hyaluronic acid and collagen may be crosslinked in aqueous solution as described herein. The crosslinked macromolecular matrices obtained in this process may be used as a hydrogel for implants and fillers for human aesthetic and therapeutic products.
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公开(公告)号：EP3357519A1
公开(公告)日：2018-08-08
申请号：EP18156418.8
申请日：2009-07-02
申请人： ALLERGAN, INC.
发明人： Van Epps, Dennis E.
IPC分类号： A61L27/18 , A61L27/38 , A61L27/58 , A61L26/00 , A61L27/20 , A61L27/24 , A61L27/26 , A61L27/50
CPC分类号： A61L27/48 , A61L27/3839 , A61L27/52 , A61L2400/06 , A61L2430/34 , G06Q40/12 , C08L89/06 , C08L5/08
摘要： Injectable compositions are provided which include both a living cellular component and a filler component conducive to cell growth. The compositions are capable of providing both immediate tissue filling and long term tissue regeneration.
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公开(公告)号：EP3354258A1
公开(公告)日：2018-08-01
申请号：EP17305105.3
申请日：2017-01-31
申请人： Teoxane SA
CPC分类号： A61K9/0063 , A61K47/36 , A61L27/20 , A61L27/52 , A61L27/54 , A61L2300/402 , A61L2300/406 , A61L2400/06 , A61L2430/12 , C08L5/08 , A61K6/0017
摘要： The present invention relates to a sterile and injectable gel comprising at least one crosslinked hyaluronic acid or a salt thereof and at least one non-crosslinked hyaluronic acid or a salt thereof for use in preventing and/or treating periodontal diseases and/or associated troubles and disorders, wherein said gel has a cross-over stress greater than or equal to 400 Pa and/or a compressive strength greater than or equal to 20 N.s.
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公开(公告)号：EP3349782A2
公开(公告)日：2018-07-25
申请号：EP16770237.2
申请日：2016-09-15
申请人： Histide AG
发明人： ZOUANI, Omar F. , GOCHEVA, Veronika
IPC分类号： A61K38/18 , A61L27/12 , A61L27/34 , A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61L27/54 , A61K9/16 , G06F19/16 , A61P35/00
CPC分类号： A61K38/18 , A61K38/05 , A61K38/07 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/1875 , A61K47/50 , A61L27/12 , A61L27/22 , A61L27/24 , A61L27/34 , A61L27/40 , A61L27/54 , A61L2300/416 , A61L2400/06 , A61L2430/02
摘要： The present disclosure provides a pharmaceutical association for use in the treatment, prevention and/or diagnostic of a neoplastic disease, said association comprising at least one growth factor receptor-binding compound, which activates at least one growth factor receptor of a neoplastic cell, and at least one bioactive carrier forming at least one covalent or non-covalent interaction with said at least one growth factor receptor-binding compound, and wherein said association reduces or suppresses, in the neoplastic cell, the gene expression of at least one cyclin D and/or reduces or suppresses the formation of at least one complex formed between said at least one cyclin D and at least one of cyclin dependent-kinase 4 or 6.
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10.发明授权
公开(公告)号：EP2841114B1
公开(公告)日：2018-06-13
申请号：EP13724891.0
申请日：2013-04-23
申请人： Genís hf.
CPC分类号： A61L27/20 , A61L24/0084 , A61L24/08 , A61L27/12 , A61L27/46 , A61L27/54 , A61L2300/412 , A61L2400/06 , A61L2430/02 , C08K3/24 , C08K5/09 , C08L5/08
摘要： The solids fraction comprises the PDC material and calcium phosphate and the liquid fraction comprises water and an acid.
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