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1.发明授权A mutant acetolactate synthase and a method for producing branched-chain L-amino acids 有权突变乙酰乳酸Snythase和用于制备支链L-氨基酸的程序
公开(公告)号：EP1942183B1
公开(公告)日：2009-10-28
申请号：EP07017918.9
申请日：2007-09-12
申请人： Ajinomoto Co., Inc.
发明人： Sycheva, Elena Viktorovna , Serebryanyy, Vsevolod Aleksandrovich , Yampolskaya, Tatyana Abramovna , Preobrazhenskaya, Ekaterina Sergeevna , Stoynova, Natalia Viktorovna
IPC分类号： C12N9/88 , C07K14/245
CPC分类号： C12P13/08 , C12N9/1022 , C12N9/88 , C12P13/06 , C12Y202/01006 , Y02P20/52
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2.发明授权A method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family 有权一种用于生产使用肠杆菌科的细菌的L-氨基酸的过程
公开(公告)号：EP2484690B1
公开(公告)日：2015-02-25
申请号：EP12001708.2
申请日：2011-01-03
申请人： Ajinomoto Co., Inc.
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3.发明授权A method for producing an L-amino acid using a bacterium of the enterobacteriaceae family 有权一种用于生产使用肠杆菌科的细菌的L-氨基酸的过程
公开(公告)号：EP2345667B1
公开(公告)日：2013-11-20
申请号：EP11000006.4
申请日：2011-01-03
申请人： Ajinomoto Co., Inc.
发明人： Savrasova, Ekaterina Alekseevna , Stoynova, Natalia Viktorovna , Nonaka, Gen , Yamazaki, Shunsuke , Takumi, Kazuhiro
摘要： A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine.
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4.发明授权A method for producing an L-amino acid using a bacterium of the family Enterobacteriaceae having attenuated expression of the yjjK gene 有权一种用于生产使用肠杆菌科的细菌的L-氨基酸的过程具有衰减的基因的表达yjjK
公开(公告)号：EP2796560B1
公开(公告)日：2016-06-29
申请号：EP14165592.8
申请日：2014-04-23
申请人： Ajinomoto Co., Inc.
发明人： Stoynova, Natalia Viktorovna , Samsonov, Valery Vasilievich , Eremina, Natalia Sergeevna , Polyakova, Evgeniya Aleksandrovna
IPC分类号： C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/24
CPC分类号： C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/22 , C12P13/222 , C12P13/225 , C12P13/227 , C12P13/24
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5.发明公开A method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family 有权一种用于生产使用肠杆菌科的细菌的L-氨基酸的过程
公开(公告)号：EP2484690A1
公开(公告)日：2012-08-08
申请号：EP12001708.2
申请日：2011-01-03
申请人： Ajinomoto Co., Inc.
发明人： Savrasova, Ekaterina Alekseevna , Stoynova, Natalia Viktorovna , Nonaka, Gen , Yamazaki, Shunsuke , Takumi, Kazuhiro
摘要： A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine.
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6.发明公开A method for producing an L-amino acid using a bacterium of the enterobacteriaceae family 有权一种用于生产使用肠杆菌科的细菌的L-氨基酸的过程
公开(公告)号：EP2345667A3
公开(公告)日：2011-09-21
申请号：EP11000006.4
申请日：2011-01-03
申请人： Ajinomoto Co., Inc.
发明人： Savrasova, Ekaterina Alekseevna , Stoynova, Natalia Viktorovna , Nonaka, Gen , Yamazaki, Shunsuke , Takumi, Kazuhiro
摘要： A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine.
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公开(公告)号：EP3085705B1
公开(公告)日：2018-06-13
申请号：EP16166148.3
申请日：2016-04-20
申请人： Ajinomoto Co., Inc.
发明人： Hook, Christina Dmitrievna , Samsonov, Valery Vasilievich , Eremina, Natalia Sergeevna , Stoynova, Natalia Viktorovna , Sidorova, Tatiyana Sergeevna
IPC分类号： C07K14/245 , C12P13/06
CPC分类号： C12P13/06 , C07K14/245
摘要： The present invention provides a method for producing L-isoleucine by fermentation using a bacterium belonging to the family Enterobacteriaceae which has been modified to overexpress the cycA gene. The method also allows reducing production of byproduct amino acid(s) of L-isoleucine during fermentation of the Enterobacteriaceae bacterium having an L-isoleucine-producing ability.
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8.发明公开A METHOD FOR PRODUCING L-ISOLEUCINE USING A BACTERIUM OF THE FAMILY ENTEROBACTERIACEAE HAVING OVEREXPRESSED THE CYCA GENE 有权用于生产L-异亮氨酸使用肠杆菌科细菌WITH THE过表达CYCA GENE
公开(公告)号：EP3085705A1
公开(公告)日：2016-10-26
申请号：EP16166148.3
申请日：2016-04-20
申请人： Ajinomoto Co., Inc.
发明人： Hook, Christina Dmitrievna , Samsonov, Valery Vasilievich , Eremina, Natalia Sergeevna , Stoynova, Natalia Viktorovna , Sidorova, Tatiyana Sergeevna
IPC分类号： C07K14/245 , C12P13/06
CPC分类号： C12P13/06 , C07K14/245
摘要： The present invention provides a method for producing L-isoleucine by fermentation using a bacterium belonging to the family Enterobacteriaceae which has been modified to overexpress the cycA gene. The method also allows reducing production of byproduct amino acid(s) of L-isoleucine during fermentation of the Enterobacteriaceae bacterium having an L-isoleucine-producing ability.
摘要翻译： 本发明提供了使用属于肠杆菌科其已经被修饰以过表达基因CYCA的细菌通过发酵生产L-异亮氨酸的方法。 因此，该方法允许降低具有L-异亮氨酸生产能力的细菌肠杆菌发酵过程中生产的L-异亮氨酸的副产物氨基酸（一个或多个）。
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9.发明公开A method for producing an L-amino acid using a bacterium of the family Enterobacteriaceae having attenuated expression of the yjjK gene 有权一种用于生产使用肠杆菌科的细菌的L-氨基酸的过程具有衰减的基因的表达yjjK
公开(公告)号：EP2796560A1
公开(公告)日：2014-10-29
申请号：EP14165592.8
申请日：2014-04-23
申请人： Ajinomoto Co., Inc.
发明人： Stoynova, Natalia Viktorovna , Samsonov, Valery Vasilievich , Eremina, Natalia Sergeevna , Polyakova, Evgeniya Aleksandrovna
IPC分类号： C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/24
CPC分类号： C12P13/04 , C12P13/06 , C12P13/08 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12P13/22 , C12P13/222 , C12P13/225 , C12P13/227 , C12P13/24
摘要： The present invention provides a method for producing L-amino acids by fermentation using a bacterium of the family Enterobacteriaceae, particularly a bacterium belonging to the genus Escherichia, which has been modified to attenuate expression of the yjjK gene.
摘要翻译： 本发明提供了用于使用肠杆菌科，特别是属于埃希氏菌属，其已经被修饰以衰减基因yjjK的表达的细菌的细菌通过发酵生产L-氨基酸的方法。
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10.发明公开A method for producing an L-amino acid using a bacterium of the enterobacteriaceae family 有权一种用于生产使用肠杆菌科的细菌的L-氨基酸的过程
公开(公告)号：EP2345667A2
公开(公告)日：2011-07-20
申请号：EP11000006.4
申请日：2011-01-03
申请人： Ajinomoto Co., Inc.
发明人： Savrasova, Ekaterina Alekseevna , Stoynova, Natalia Viktorovna , Nonaka, Gen , Yamazaki, Shunsuke , Takumi, Kazuhiro
摘要： A method for producing an L-amino acid is described using a bacterium of the Enterobacteriaceae family, wherein the bacterium contains a protein which is able to confer resistance to growth inhibition by L-cysteine.
摘要翻译： 一种用于在L-氨基酸的制造方法是使用肠杆菌科的细菌，worin细菌含有蛋白质的所有其能够由L-半胱氨酸以赋予生长抑制的抗性说明。
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