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公开(公告)号：EP3404101A3
公开(公告)日：2018-12-26
申请号：EP18182250.3
申请日：2012-12-21
发明人： LEE, Kwang Ho , LIM, Sang Jo , MOON, Jun Ok , JANG, Jae Woo , PARK, Su Jin , PARK, Sang Hee
CPC分类号： C12P13/08 , C12N9/1022 , C12N9/1217 , C12N9/93 , C12N15/52 , C12N15/63 , C12N15/74 , C12Y202/01001 , C12Y207/02004 , C12Y604/01001 , Y02P20/52
摘要： The present invention relates to a modified polynucleotide encoding aspartate kinase (EC:2.7.2.4; hereinafter, referred to as LysC), transketolase (EC:2.2.1.1; hereinafter, referred to as Tkt) or pyruvate carboxylase (EC:6.4.1.1; hereinafter, referred to as Pyc), in which the initiation codon is substituted with ATG, a vector including the same, a microorganism transformed with the vector, and a method for producing L-lysine using the same.
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公开(公告)号：EP3204405A4
公开(公告)日：2018-03-07
申请号：EP14903578
申请日：2014-10-09
发明人： CHOU HOWARD , LIU XIUCAI
IPC分类号： C07K14/245 , C07K14/35 , C07K14/36 , C12N1/21 , C12N9/88 , C12N15/31 , C12N15/67 , C12N15/70 , C12N15/77 , C12P13/00 , C12P13/08 , C12R1/15 , C12R1/19
CPC分类号： C07K14/245 , C07K14/35 , C07K14/36 , C12N9/88 , C12N15/70 , C12N15/77 , C12P13/001 , C12P13/08
摘要： The present invention provides a mutant polypeptide comprising the amino acid sequence of Escherichia coli tetracycline efflux pump A (TetA), and a polynucleotide encoding the polypeptide. The present invention provides a first expression plasmid vector comprising one or more first polynucleotides encoding a tetracycline efflux pump, one or more second polynucleotides independently selected from the group consisting of a third polynucleotides encoding a lysine decarboxylase polypeptide and a fourth polynucleotides encoding a lysine biosynthesis polypeptide, and a transformant comprising the expression plasmid vector. The present invention provides a host cell comprising one or more first, third or fourth polynucleotides as described herein integrated into a chromosome of the host cell. The present invention also provides a method for producing a lysine of a cadaverine using the transformant and/or the host cell.
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5.发明公开GLUCONATE REPRESSOR VARIANT, L-LYSINE PRODUCING MICROORGANISM COMPRISING SAME, AND METHOD FOR PRODUCING L-LYSINE USING SAME 审中-公开葡糖酸盐阻遏物变体，包含其的L-赖氨酸生产微生物，以及使用相同方法生产L-赖氨酸的方法
公开(公告)号：EP3287469A1
公开(公告)日：2018-02-28
申请号：EP16783326.8
申请日：2016-03-11
发明人： PARK, Sang Hee , KIM, Hyung Joon , KIM, Nam Hyun , MOON, Jun Ok , OH, Jeong Seok , RYU, Song-Gi , CHOI, Hyang
IPC分类号： C07K14/195 , C07K14/34
CPC分类号： C12P13/08 , C07C229/26 , C07K14/195 , C07K14/34 , C12N15/77
摘要： The present invention relates to a novel gluconate repressor variant, a microorganism containing the same, and a method for producing L-lysine using the same.
摘要翻译： 本发明涉及一种新型葡糖酸盐阻遏物变体，含有该葡萄糖酸盐阻遏物变体的微生物以及使用该葡萄糖酸盐阻遏物变体生产L-赖氨酸的方法。
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6.发明公开
公开(公告)号：EP3196300A4
公开(公告)日：2018-01-31
申请号：EP15837358
申请日：2015-09-04
申请人： CJ CHEILJEDANG CORP
发明人： HUH LAN , LEE KWANG HO , KIM HYUNG JOON , MOON JUN OK , RYU SONG-GI
摘要： The present disclosure relates to a novel modified RNA polymerase sigma factor A (SigA) polypeptide; a polynucleotide encoding the same; a microorganism containing the polypeptide; and a method for producing L-lysine using the microorganism.
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公开(公告)号：EP3250692A1
公开(公告)日：2017-12-06
申请号：EP16743624.5
申请日：2016-01-15
申请人： CJ Cheiljedang Corp.
发明人： LEE, Seung Bin , BAE, Hyun Ae , LEE, Ji Hye , YANG, Young Lyeol
摘要： Provided are a novel promoter and a method of producing a target product using the same.
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8.发明授权Microorganism producing L-threonine having inactivated tyR gene, method of producing the same and method of producing L-threonine using the microorganism 有权生产具有灭活tyR基因的微生物L-苏氨酸，其生产方法和使用该微生物生产L-苏氨酸的方法
公开(公告)号：EP1591520B1
公开(公告)日：2017-11-29
申请号：EP05356023.1
申请日：2005-02-04
发明人： Park, Young Hoon, 111-102 Mujigae Daerim Apt. , Lee, Byoung Choon , Park, Jae Yong , Cho, Kwang Myung , Shin, Yong Uk
IPC分类号： C12N1/20 , C12P13/08 , C07K14/245 , C12R1/19
CPC分类号： C12P13/08
摘要： Provided are a microorganism capable of producing L-threonine and having an inactivated tyrR gene, a method of producing the same and a method of producing L-threonine using the microorganism. The microorganism can be used to produce L-threonine in high yield.
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9.发明公开
公开(公告)号：EP3119875A4
公开(公告)日：2017-11-15
申请号：EP15765883
申请日：2015-03-17
申请人： CJ CHEILJEDANG CORP
发明人： LEE JI SUN , SEO CHANG IL , CHEONG KI YONG , KOH EUN SUNG , KWON DO HYUN , LEE KWANG HO
IPC分类号： C12N15/70 , C07K14/245 , C12P13/08 , C12P13/22
CPC分类号： C12N15/70 , C07K14/245 , C12P13/08 , C12P13/227
摘要： Disclosed are a recombinant microorganism having enhanced L-amino acid producibility, wherein the recombinant microorganism is transformed to have an inactivated phage receptor thereof, and a method of producing an L-amino acid using the recombinant microorganism. The use of the recombinant microorganism may enable the production of the L-amino acid in a highly efficient manner.
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10.发明公开
公开(公告)号：EP3106516A4
公开(公告)日：2017-11-01
申请号：EP14882402
申请日：2014-04-25
申请人： CJ CHEILJEDANG CORP
发明人： KIM HYUNG JOON , KWON SU YON , KOH EUN SUNG , LEE JI SUN , LEE KEUN CHEOL , HWANG YOUNG BIN , HONG HYEONG PYO
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