公开(公告)号：EP2268625B1

公开(公告)日：2012-05-16

申请号：EP09732141.8

申请日：2009-04-06

申请人： Bayer Pharma Aktiengesellschaft

发明人： HAHN, Michael, G. ,  BECKER, Eva-Maria ,  KNORR, Andreas ,  SCHNEIDER, Dirk ,  STASCH, Johannes-Peter ,  SCHLEMMER, Karl-Heinz ,  WUNDER, Frank ,  STOLL, Frederike ,  HEITMEIER, Stefan ,  MÜNTER, Klaus ,  GRIEBENOW, Nils ,  LAMPE, Thomas ,  EL SHEIKH, Sherif ,  LI, Volkhart Min-Jian

IPC分类号： C07D253/08 ,  A61K31/5395 ,  A61K31/498 ,  A61P9/00 ,  C07D209/46 ,  C07D209/48 ,  C07D211/76 ,  C07D213/64 ,  C07D231/56 ,  C07D233/32 ,  C07D237/14 ,  C07D237/32 ,  C07D239/88 ,  C07D261/20 ,  C07D263/20 ,  C07D273/04 ,  C07D275/06 ,  C07D277/34 ,  C07D417/12 ,  C07D253/075

CPC分类号： C07D237/32 ,  C07D209/46 ,  C07D209/48 ,  C07D211/76 ,  C07D213/64 ,  C07D215/227 ,  C07D231/56 ,  C07D233/32 ,  C07D237/14 ,  C07D239/88 ,  C07D253/075 ,  C07D253/08 ,  C07D261/20 ,  C07D263/20 ,  C07D271/113 ,  C07D273/04 ,  C07D275/06 ,  C07D277/34 ,  C07D417/12

摘要： The present invention relates to novel carboxylic acid derivates of the formula (I), having an oxo-substituted azaheterocyclic partial structure, method for the production thereof, use thereof for treating and/or preventing illnesses and use thereof for producing medications for treating and/or preventing illnesses, particularly for treating and/or preventing cardiovascular diseases. The compounds act as activators of soluble guanylate cyclase.