公开(公告)号：EP3334685A1

公开(公告)日：2018-06-20

申请号：EP16745731.6

申请日：2016-07-29

申请人： Bein, Thomas ,  Engelke, Hanna ,  Feckl, Johann ,  Freiherr von Schirnding, Constantin ,  Ludwig-Maximilians-Universität München

发明人： BEIN, Thomas ,  ENGELKE, Hanna ,  FREIHERR VON SCHIRNDING, Constantin ,  FECKL, Johann

IPC分类号： C01B25/32 ,  A61K9/127 ,  A61K9/51

CPC分类号： A61K9/5115 ,  A61K9/1272 ,  A61K47/02 ,  A61K47/12 ,  A61K47/186 ,  A61K47/24 ,  A61K47/42 ,  B82Y5/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B25/32 ,  C01P2004/64 ,  C01P2006/12 ,  C01P2006/14 ,  C01P2006/16 ,  C02F1/288 ,  C05B17/00

摘要： The present invention relates to mesoporous calcium phosphate-citrate nanoparticles, optionally comprising a lipid membrane, and pharmaceutical compositions thereof. The present invention further relates to a method of synthesizing the mesoporous calcium phosphate-citrate nanoparticles. The present invention relates to their use as drug delivery system. The present invention further relates to medical uses as bone or teeth cement, bone material or taste or non-taste masked carrier or delivery system. The present invention relates to the use of the mesoporous calcium phosphate-citrate nanoparticles in the diagnosis and/or treatment of cancer. The present invention further relates to the use of the mesoporous calcium phosphate-citrate nanoparticles in fertilizer or absorber of metal ions from wastewater and/or water.