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1.发明公开
公开(公告)号：EP4400119A3
公开(公告)日：2024-09-25
申请号：EP24172897.1
申请日：2019-04-09
发明人： Denk, Oliver , Börner, Gerhard , Iacono, Aldo
CPC分类号： A61K9/127 , A61K9/19 , A61K38/13 , A61K9/0078 , A61K47/24 , A61K47/26 , A61K47/183 , A61K47/02
摘要： The present invention relates to a composition comprising cyclosporine A (CsA) for use in the prevention of bronchiolitis obliterans syndrome (BOS) in a double lung transplanted patient, or for the treatment of BOS or for the prevention or delay of the progression of BOS in a double lung transplanted patient being diagnosed with BaS,
wherein the composition is administered to said patient by inhalation of said composition in aerosolized form comprising a therapeutically effective dose of cyclosporine A.-
2.发明授权
公开(公告)号：EP4069206B8
公开(公告)日：2024-09-18
申请号：EP20829657.4
申请日：2020-12-04
IPC分类号： A61K9/00 , A61K9/107 , A61K9/16 , A61K47/14 , A61K47/36 , A61K47/24 , A61K31/4402 , A61P3/10 , A61P21/00 , A61K33/24 , A61P3/02
CPC分类号： A61K9/0095 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K47/14 , A61K47/24 , A61K47/36 , A61K9/1075 , A61P21/00 , A61P3/10 , A61P3/02 , A61K33/24 , A61K31/4402
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公开(公告)号：EP4167959B1
公开(公告)日：2024-08-28
申请号：EP21743229.3
申请日：2021-06-21
IPC分类号： A61K8/34 , A61K8/365 , A61K8/891 , A61K9/107 , A61K31/05 , A61K31/07 , A61K31/17 , A61K31/192 , A61K31/203 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/24 , A61P17/00 , A61Q19/00 , A61K8/49 , A61K8/894 , A61K8/898 , A61P35/00 , A61K8/67
CPC分类号： A61K9/0014 , A61K9/107 , A61K47/12 , A61K47/18 , A61K47/10 , A61K47/24 , A61K31/05 , A61K31/352 , A61K31/522 , A61K31/4174 , A61K31/496 , A61K31/192 , A61K31/4436 , A61K31/203 , A61K31/07 , A61K31/436 , A61K31/728 , A61K31/17 , A61K31/573 , A61K31/58 , A61K31/56 , A61K31/593 , A61K31/455 , A61P17/00 , A61Q19/00 , A61K8/891 , A61K8/342 , A61K8/345 , A61K8/365 , A61K8/675 , A61K8/898 , A61K8/894 , A61K8/4913 , A61P35/00 , A61K31/047 , A61K31/7032 , A61K31/366
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5.发明公开
公开(公告)号：EP4417197A1
公开(公告)日：2024-08-21
申请号：EP22881197.2
申请日：2022-08-26
申请人： Samsung Life Public Welfare Foundation , Research & Business Foundation SungKyunKwan University
发明人： KIM, Jeong Hoon , JACKMAN, Joshua Alexander , JEONG, Byong Chang , MOON, Sue Jin , YOON, Bo Kyeong , JEON, Won Yong
摘要： The present invention relates to a pharmaceutical composition for the treatment of castration-resistant prostate cancer, comprising bruceantin and nanoparticles. Using the composition comprising bruceantin and nanoparticles according to an embodiment, it is possible to effectively treat castration-resistant prostate cancer by reducing the side effects of bruceantin and overcoming the poor solubility thereof.
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公开(公告)号：EP4397368A2
公开(公告)日：2024-07-10
申请号：EP24178043.6
申请日：2017-06-16
发明人： MENNE, Torkil , SELMER, Johan , LANGE, Jesper , GEORGIOU, Michelle , WHEELER, Derek , EVANS, David
IPC分类号： A61P17/04
CPC分类号： A61K31/4172 , A61P17/04 , A61K45/06 , A61K31/4015 , A61K9/0014 , A61K47/06 , A61K47/08 , A61K47/10 , A61K47/14 , A61K47/186 , A61K47/20 , A61K47/24 , A61K47/26 , A61K9/06 , A61K47/32 , A61K47/44
摘要： There is provided a topical formulation comprising a nucleophile, such as amino acids and most polypetides and/or a derivative thereof, for use in the treatment or prevention of itchy dry skin caused by urea, such as in uremic pruritus, of a subject. The amino acid may be histidine and the derivative may be a histidine degradation product, a peptide of histidine, a peptide of histidine and one or more additional amino acids, and a pharmaceutically- acceptable salt of histidine.
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公开(公告)号：EP4373524A1
公开(公告)日：2024-05-29
申请号：EP22846562.1
申请日：2022-07-20
CPC分类号： A61P31/02 , A61K41/0071 , A61K47/10 , A61K47/26 , A61K47/24 , A61K47/38 , A61K47/32 , A61K9/0014 , A61K9/06 , A61K47/20
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公开(公告)号：EP4360624A1
公开(公告)日：2024-05-01
申请号：EP22828788.4
申请日：2022-06-23
申请人： Therna Therapeutics
发明人： LEE, Taewoo , BAEK, Yu Mi , RYU, Jiwon , JANG, Dahye
IPC分类号： A61K9/51 , A61K47/18 , A61K47/26 , A61K47/28 , A61K47/24 , A61K31/7088 , A61K47/10 , A61K48/00
CPC分类号： A61K9/51 , A61K47/10 , A61K47/24 , A61K48/00 , A61K47/26 , A61K47/28 , A61K31/7088 , A61K47/18
摘要： The present invention relates to lipid nanoparticles and a method for preparing same and, more specifically, to particles containing an ionizable lipid and a polyethylene glycol moiety (PEG moiety)-degradable liking functional group-lipid conjugate, which are characterized by minimized side effects in vivo and effective nanoparticle transfer into target cells so as to deliver pharmaceutically effective materials into the cytoplasm.
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公开(公告)号：EP4358936A1
公开(公告)日：2024-05-01
申请号：EP22735885.0
申请日：2022-06-22
申请人： Bio-TRIP B.V.
发明人： VAN DER MEEL, Roy , MULDER, Willem J.M. , KLUZA, Ewelina , HOFSTRAAT, Stijn , ANBERGEN, Tom , ZWOLSMAN, Robby Cornelis , JANSSEN, Henricus Marie , FRANSEN, Pieter Michele
CPC分类号： A61K9/127 , A61K9/0019 , A61K9/5123 , A61P37/06 , A61P9/00 , A61K47/24 , A61K47/18 , A61K47/14 , A61K31/713
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