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1.发明授权
公开(公告)号：EP1154788B9
公开(公告)日：2007-09-12
申请号：EP00909162.0
申请日：2000-02-14
发明人： UHLMANN, Frank , NASMYTH, Kim , PETERS, Jan-Michael , WAIZENEGGER, Irene , BUONOMO, Sara , CLYNE, Rosemary
CPC分类号： G01N33/5011 , G01N2800/7023
摘要： Method for identifying compounds that interfere with or modulate sister chromatid separation in animal or plant cells by modulating a protease with separin-like cysteine endopeptidase activity. Inhibitors of separin activity are useful in cancer therapy, to prevent birth defects and to increase ploidy in plants.
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公开(公告)号：EP1154788A1
公开(公告)日：2001-11-21
申请号：EP00909162.0
申请日：2000-02-14
发明人： UHLMANN, Frank , NASMYTH, Kim , PETERS, Jan-Michael , WAIZENEGGER, Irene , BUONOMO, Sara , CLYNE, Rosemary
CPC分类号： G01N33/5011 , G01N2800/7023
摘要： Method for identifying compounds that interfere with or modulate sister chromatid separation in animal or plant cells by modulating a protease with separin-like cysteine endopeptidase activity. Inhibitors of separin activity are useful in cancer therapy, to prevent birth defects and to increase ploidy in plants.
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公开(公告)号：EP1154788B1
公开(公告)日：2007-07-11
申请号：EP00909162.0
申请日：2000-02-14
发明人： UHLMANN, Frank , NASMYTH, Kim , PETERS, Jan-Michael , WAIZENEGGER, Irene , BUONOMO, Sara , CLYNE, Rosemary
CPC分类号： G01N33/5011 , G01N2800/7023
摘要： Method for identifying compounds that interfere with or modulate sister chromatid separation in animal or plant cells by modulating a protease with separin-like cysteine endopeptidase activity. Inhibitors of separin activity are useful in cancer therapy, to prevent birth defects and to increase ploidy in plants.
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