NOVEL, RECOMBINANTLY PRODUCED SPIDER SILK ANALOGS
    6.
    发明公开
    NOVEL, RECOMBINANTLY PRODUCED SPIDER SILK ANALOGS 失效
    新颖,重组生产的蜘蛛丝类似物

    公开(公告)号:EP0707645A1

    公开(公告)日:1996-04-24

    申请号:EP94920732.0

    申请日:1994-06-15

    IPC分类号: C12N1 C07K14 C12N15 C12R1 F02B75

    CPC分类号: C07K14/43518 F02B2075/027

    摘要: The invention relates to novel spider silk protein analogs derived from the amino acid consensus sequence of repeating units found in the natural spider dragline of Nephila clavipes. More specifically, synthetic spider dragline has been produced from E. coli and Bacillus subtilis recombinant expression systems wherein expression from E. coli is at levels greater than 1 mg full-length polypeptide per gram of cell mass.

    摘要翻译: 本发明涉及新颖的蜘蛛丝蛋白类似物,其衍生自在Nephila clavipes的天然蜘蛛牵引线中发现的重复单元的氨基酸共有序列。 更具体地说,已经从大肠杆菌和枯草芽孢杆菌重组表达系统产生了合成蜘蛛牵引线,其中来自大肠杆菌的表达的水平大于每克细胞质量1mg全长多肽。