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公开(公告)号：EP2818542A1
公开(公告)日：2014-12-31
申请号：EP12864324.4
申请日：2012-12-28
申请人： Hitachi Chemical Company, Ltd. , National University Corporation Tokyo University Of Agriculture and Technology
发明人： KIKUHARA Yoshihito , KANBARA Hisashige , SUZUKI Takahiro , MATSUNAGA Tadashi , YOSHINO Tomoko , HOSOKAWA Masahito
IPC分类号： C12M1/28
CPC分类号： G01N1/4005 , B01L3/502753 , B01L2300/0681 , B01L2300/0874 , C12M47/02 , G01N15/0272 , G01N15/06 , G01N2001/4088 , G01N2015/0065
摘要： A cell trapping device includes a housing that includes an inlet opening connected to an inlet line through which a cell dispersion liquid is introduced and an outlet opening connected to an outlet line through which the cell dispersion liquid is discharged; and a filter which is positioned within the housing and includes a trapping region for trapping cancer cells contained in the cell dispersion liquid. The filter is bonded to the housing, at least a part of the trapping region is formed of an observation region for observing the trapping region from the outside, the inlet line and the inlet opening are arranged at outer positions than the observation region when viewed from a normal line direction of the filter, and the inlet line is extended along an in-plane direction of the filter.
摘要翻译： 细胞捕获装置包括：壳体，其包括连接到入口线的入口开口，细胞分散液通过所述入口引入，并且出口开口连接到排出细胞分散液体的出口线; 以及位于壳体内并且包含用于捕获包含在细胞分散液中的癌细胞的捕获区域的过滤器。 过滤器结合到壳体，捕集区域的至少一部分由用于从外部观察捕获区域的观察区域形成，入口管线和入口开口布置在比从观察区域观察的外部位置 过滤器的法线方向，并且入口管线沿着过滤器的面内方向延伸。
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公开(公告)号：EP2767618B1
公开(公告)日：2017-07-19
申请号：EP12839364.2
申请日：2012-10-09
CPC分类号： B01D29/012 , A61M1/36 , A61M2207/00 , C25D1/00 , C25D1/08 , C25D3/12 , G03F7/0015
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公开(公告)号：EP2982743A1
公开(公告)日：2016-02-10
申请号：EP14778952.3
申请日：2014-03-04
发明人： TAKAI Kenji , YAGI Satomi , SUZUKI Takahiro , EJIRI Yoshinori , YAMAMOTO Hiroshi , TAKAHASHI Akio
IPC分类号： C12M1/26
CPC分类号： B01D39/10 , B01D2239/0478
摘要： A biomolecule capturing filter, comprising a gold plating on the surface of a biomolecule capturing filter made of a metal other than gold, the gold plating being electroless gold plating is disclosed.
摘要翻译： 本发明公开了一种生物分子捕获过滤器，其包括在除金之外的金属制成的生物分子捕获过滤器的表面上的金镀层，所述金镀层是无电镀金。
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4.发明公开CANCER CELL-TRAPPING METAL FILTER, CANCER CELL-TRAPPING METAL FILTER SHEET, CANCER CELL-TRAPPING DEVICE, AND MANUFACTURING METHODS THEREFOR 审中-公开癌细胞DETECT SANTANDER金属过滤膜检测金属过滤器，癌症检测设备及其制造方法癌细胞
公开(公告)号：EP2851418A1
公开(公告)日：2015-03-25
申请号：EP13791257.2
申请日：2013-05-10
CPC分类号： C12N5/0694 , B01D39/10 , B22D25/02 , B22D29/00 , C08J5/121 , C08J2300/12 , G01N1/4077 , G01N33/49 , G01N2001/4088 , G03F7/038 , G03F7/039 , G03F7/2004 , G03F7/322 , G03F7/405 , G03F7/428 , Y10T29/49 , Y10T156/10
摘要： Provided are a cancer cell-trapping metal filter which has a high opening ratio, a cancer cell-trapping metal filter sheet, a cancer cell-trapping device using the cancer cell-trapping filter, and manufacturing methods therefor.
According to a cancer cell-trapping metal filter 1, openings of connected through-holes 12 that are formed in a metal sheet 11 have a wave shape, and thus it is possible to extract a CTC from other components by utilizing a hole diameter on a short-side side of the openings, and it is possible to make the connected through-holes be closer to each other due to the wave shape while maintaining a CTC trapping ability. Accordingly, it is possible to further improve the opening ratio in the cancer cell-trapping metal filter 1.摘要翻译： 本发明提供一种癌症细胞捕获金属过滤器具有高的开口率，癌症细胞捕获金属过滤片，使用癌症细胞捕获过滤器的癌症细胞捕获装置，及其制造方法。 。根据癌症细胞捕获金属过滤器1，连接通孔12并在金属片11具有波浪形状形成开口部，因此，能够通过在利用一个孔的直径从其它组分中提取CTC 开口的短边侧，并且有可能使连接的通孔更接近海誓山盟由于波浪形状，同时保持CTC捕集能力。 因此，能够つweiterer第一改善癌症细胞捕获金属过滤器的开口率
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公开(公告)号：EP2767618A1
公开(公告)日：2014-08-20
申请号：EP12839364.2
申请日：2012-10-09
CPC分类号： B01D29/012 , A61M1/36 , A61M2207/00 , C25D1/00 , C25D1/08 , C25D3/12 , G03F7/0015
摘要： A method for producing a metal filter comprising a lamination step of laminating a photosensitive resin composition on a copper substrate to form a photosensitive resin composition layer, an exposure step of irradiating a predetermined portion of the photosensitive resin composition layer with an active light and light-curing the exposed portion to form a cured material of the photosensitive resin composition, a development step of removing a portion other than the cured material of the photosensitive resin composition of the photosensitive resin composition layer by development to form a resist pattern composed of the cured material of the photosensitive resin composition on the copper substrate, a plating step of metal plating the resist-patterned copper substrate to form a plated layer, a dissolution step of removing the copper substrate with chemical dissolution to obtain a structure composed of the plated layer and the cured material of the photosensitive resin composition, and a stripping step of removing the cured material of the photosensitive resin composition from the structure to obtain the plated layer, wherein the plated layer is the metal filter is useful because it is possible to produce a metal filter in which there are not damages such as wrinkles, folds, scars, and curls and deformation of fine through-holes.
摘要翻译： 一种金属过滤器的制造方法，其特征在于，包括将感光性树脂组合物层叠在铜基板上以形成感光性树脂组合物层的层叠工序，使用活性光照射光敏树脂组合物层的规定部分的曝光工序， 固化曝光部分以形成感光性树脂组合物的固化材料，显影步骤，通过显影除去感光性树脂组合物层的感光性树脂组合物的固化物以外的部分，形成由固化物构成的抗蚀剂图案 所述感光性树脂组合物在所述铜基板上的电镀步骤，对所述抗蚀剂图案化铜基板进行金属电镀以形成镀层的镀敷步骤，通过化学溶解除去所述铜基板的溶解步骤，得到由所述镀层和 感光性树脂组合物的固化物，和a 从该结构中除去感光性树脂组合物的固化物的剥离工序，得到镀层，其中，镀层是金属过滤器是有用的，因为可以制造没有损伤如金属过滤器的金属过滤器， 褶皱，疤痕，以及细通孔的卷曲和变形。
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