公开(公告)号：EP3615517A1

公开(公告)日：2020-03-04

申请号：EP18719875.9

申请日：2018-04-25

申请人： Horitzonts Technologics Hungary Korlatolt Felelossegu Tarsasag

发明人： HERNÁNDEZ CABANILLAS, Alfredo ,  MADERUELO CORRAL, Santiago ,  ORTEGA DOMÉNECH, Montserrat ,  ROSERO VALENCIA, Diego Fernando ,  RUMBERO SÁNCHEZ, Ángel ,  TENA PÉREZ, Víctor

IPC分类号： C07D273/04 ,  A61K31/5395 ,  A61P31/04 ,  A61P31/10 ,  A61P31/12 ,  A61P31/18 ,  A61P35/00

公开(公告)号：EP3395805A1

公开(公告)日：2018-10-31

申请号：EP17382224.8

申请日：2017-04-26

申请人： Horitzonts Technologics Hungary Korlatolt Felelossegu Tarsasag

发明人： HERNÁNDEZ CABANILLAS, Alfredo ,  MADERUELO CORRAL, Santiago ,  ORTEGA DOMÉNECH, Montserrat ,  ROSERO VALENCIA, Diego Fernando ,  RUMBERO SÁNCHEZ, Ángel ,  TENA PÉREZ, Víctor

IPC分类号： C07D273/04 ,  A61K31/5395 ,  A61P31/04 ,  A61P31/10 ,  A61P31/12 ,  A61P31/18 ,  A61P35/00

CPC分类号： C07D273/04 ,  A61P31/04 ,  A61P31/10 ,  A61P31/12 ,  A61P31/18 ,  A61P35/00

摘要： The invention relates to novel compounds of formula (I), wherein one Z is N and the other is -C-R 2 , and their use in medicine, particularly in treating and /or preventing infections caused by a bacterium, fungus or virus or in treating and/or preventing cancer. Additionally, the invention relates to a process for obtaining the compounds of the invention.

公开(公告)号：EP3976045A1

公开(公告)日：2022-04-06

申请号：EP20728089.2

申请日：2020-06-01

申请人： Horitzonts Technologics Hungary Korlatolt Felelossegu Tarsasag

发明人： HERNÁNDEZ CABANILLAS, Alfredo ,  MADERUELO CORRAL, Santiago ,  ORTEGA DOMÉNECH, Montserrat ,  ROSERO VALENCIA, Diego Fernando ,  RUMBERO SÁNCHEZ, Ángel ,  TENA PÉREZ, Víctor ,  APAZA TICONA, Luis Néstor

IPC分类号： A61K31/5395 ,  A23L29/00 ,  A61K8/30 ,  A61P29/00 ,  A61P39/06 ,  A23L5/20 ,  A23L5/41 ,  A61K8/49 ,  A23B7/154 ,  A23L3/3544 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A23L33/10

公开(公告)号：EP3744329A1

公开(公告)日：2020-12-02

申请号：EP19382449.7

申请日：2019-05-31

申请人： Horitzonts Technologics Hungary Korlatolt Felelossegu Tarsasag

发明人： HERNÁNDEZ CABANILLAS, Alfredo ,  MADERUELO CORRAL, Santiago ,  ORTEGA DOMÉNECH, Montserrat ,  ROSERO VALENCIA, Diego Fernando ,  RUMBERO SÁNCHEZ, Ángel ,  TENA PÉREZ, Víctor ,  APAZA TICONA, Luis Néstor

IPC分类号： A61K31/5395 ,  A23L29/00 ,  A61K8/30 ,  A61P29/00 ,  A61P39/06

摘要： The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer or solvate thereof for use in the prevention and/or treatment of a pathology associated with proinflammatory conditions, a disease associated with oxidative stress or production of reactive oxygen species or a skin pigmentation disorder. In addition, the invention also relates to a cosmetic method for preventing and/or treating skin aging, irradiated skin or for skin-whitening comprising administering a compound of formula (I) or a cosmetically acceptable salt, stereoisomer or solvate thereof. In addition, the invention relates to a method of inhibition of enzymatic browning in food or beverage comprising contacting said food or beverage with a compound of formula (I) or a salt, stereoisomer or solvate thereof under conditions sufficient to inhibit enzymatic browning of said food or beverage.