公开(公告)号：EP2825162B1

公开(公告)日：2018-09-12

申请号：EP13761860.9

申请日：2013-03-13

申请人： Indiana University Research and Technology Corporation

发明人： KELLEY, Mark, R. ,  FISHEL, Melissa, L. ,  CARDOSO, Angelo, A.

IPC分类号： A61K31/122 ,  A61K45/06 ,  A61K31/16 ,  A61K31/164 ,  A61K31/201 ,  A61K31/381 ,  A61K31/45 ,  A61K31/475 ,  A61K31/495 ,  A61K31/519 ,  A61K31/5375 ,  A61K31/573 ,  A61K31/704 ,  A61P35/02

CPC分类号： C07D295/192 ,  A61K31/16 ,  A61K31/164 ,  A61K31/201 ,  A61K31/381 ,  A61K31/45 ,  A61K31/475 ,  A61K31/495 ,  A61K31/519 ,  A61K31/5375 ,  A61K31/573 ,  A61K31/704 ,  A61K45/06 ,  C07C49/563 ,  C07C59/90 ,  C07C235/78 ,  C07D211/40 ,  A61K2300/00

摘要： Compounds, and methods and uses of compounds, and pharmaceutical compositions thereof, are described herein for treating leukemia. In particular, compounds, and methods and uses of compounds, and pharmaceutical compositions thereof, are described herein for treating acute lymphoblastic leukemia (ALL) in its various forms.

公开(公告)号：EP2825162A1

公开(公告)日：2015-01-21

申请号：EP13761860.9

申请日：2013-03-13

申请人： Indiana University Research and Technology Corporation

发明人： KELLEY, Mark, R. ,  FISHEL, Melissa, L. ,  CARDOSO, Angelo, A.

IPC分类号： A61K31/122 ,  A61K45/06 ,  A61K31/16 ,  A61K31/164 ,  A61K31/201 ,  A61K31/381 ,  A61K31/45 ,  A61K31/475 ,  A61K31/495 ,  A61K31/519 ,  A61K31/5375 ,  A61K31/573 ,  A61K31/704 ,  A61P35/02

CPC分类号： C07D295/192 ,  A61K31/16 ,  A61K31/164 ,  A61K31/201 ,  A61K31/381 ,  A61K31/45 ,  A61K31/475 ,  A61K31/495 ,  A61K31/519 ,  A61K31/5375 ,  A61K31/573 ,  A61K31/704 ,  A61K45/06 ,  C07C49/563 ,  C07C59/90 ,  C07C235/78 ,  C07D211/40 ,  A61K2300/00

摘要： Compounds, and methods and uses of compounds, and pharmaceutical compositions thereof, are described herein for treating leukemia. In particular, compounds, and methods and uses of compounds, and pharmaceutical compositions thereof, are described herein for treating acute lymphoblastic leukemia (ALL) in its various forms.