公开(公告)号：EP1426101B1

公开(公告)日：2011-01-05

申请号：EP02767852.3

申请日：2002-08-23

申请人： Japan Science and Technology Agency

发明人： CHIBA, Kazuhiro ,  KONO, Yusuke

IPC分类号： B01J19/00 ,  C07K1/02 ,  C07B61/00

CPC分类号： C07C69/757 ,  C07B61/00 ,  C07C43/23 ,  C07C2602/28

摘要： A solvent system which comprises two or more single or mixed organic solvents, characterized in that the state of the solvent system can be reversibly changed, with changing temperature conditions, from one state which is a homogeneously compatibilized mixed solvent system in which the two or more single or mixed organic solvents constituting the solvent system have been homogeneously compatibilized and mixed to the other state which is a separated solvent system made up of two or more separate phases respectively consisting mainly of the two or more single or mixed organic solvents constituting the solvent system, and that when the solvent system is the homogeneously mixed solvent system, a chemical ingredient which is soluble in only one of the single or mixed organic solvents can be evenly dissolved in the system; and a process for producing a compound with the solvent system.

公开(公告)号：EP1426101A1

公开(公告)日：2004-06-09

申请号：EP02767852.3

申请日：2002-08-23

申请人： Japan Science and Technology Agency

发明人： CHIBA, Kazuhiro ,  KONO, Yusuke

IPC分类号： B01J19/00

CPC分类号： C07C69/757 ,  C07B61/00 ,  C07C43/23 ,  C07C2602/28

摘要： A solvent system which comprises two or more single organic solvents or two or more mixed organic solvents, characterized in that the state of the solvent system can be reversibly changed, with changing temperature conditions, from one state which is a homogeneously compatibilized mixed solvent system in which the two or more single or more mixed organic solvents constituting the solvent system have been homogeneously compatibilized and mixed to the other state which is a separated solvent system made up of two or more separated phases respectively consisting mainly of the two or more single or mixed organic solvents constituting solvent system, and that when the solvent system is the homogeneously mixed solvent system, a chemical component which is soluble in only one of the single or mixed organic solvents can be evenly dissolved in the system; and a process for producing a compound with the solvent system.

公开(公告)号：EP1681092A1

公开(公告)日：2006-07-19

申请号：EP04792336.2

申请日：2004-10-06

申请人： Japan Science and Technology Agency

发明人： CHIBA, Kazuhiro

IPC分类号： B01J19/00 ,  C07B61/00

CPC分类号： C07C231/12 ,  B01J2219/00308 ,  B01J2219/00364 ,  B01J2219/00481 ,  B01J2219/00495 ,  B01J2219/00585 ,  B01J2219/00599 ,  B01J2219/00686 ,  B01J2219/0072 ,  C07B61/00 ,  C07C67/10 ,  C07C231/02 ,  Y10T436/25375 ,  Y10T436/255

摘要： A method for making a number (N) of samples react under the same reaction conditions, wherein the samples have a solution where the phase state of a reaction solvent changes in a reversible manner between a two-phase solution state and a uniform solution state when the temperature fluctuates over or under a certain constant temperature, and the processes are carried out sequentially in the following steps: (A) the constant container heating step of heating a number of reaction containers simultaneously and maintaining the reaction containers at a predetermined temperature; (B) the sample heating step of putting a sample in each heated reaction container and of maintaining a two-phase solution at a predetermined temperature; (C) the reaction step of stirring the sample that has been heated to the predetermined temperature so as to gain a uniform solution, which is maintained for a predetermined period of time; (D) the cooling step of cooling the uniform solution without cooling the reaction container after the predetermined period of time has passed so as to gain a two-phase solution within the reaction container.
According to the present invention, a method for making a two phase solution of which the phase state changes through temperature conversion react through a number of processes, wherein a chemical process can be carried out on a number of samples under the same conditions in one process apparatus, as well as an apparatus for implementing this can be provided.

摘要翻译： 一种用于制备样本的数目（N）的方法相同的反应条件，worin样品具有的溶液下反应，其中的两相溶液状态和均匀的溶液状态。当之间以可逆的方式进行反应的相态溶剂改变 温度波动超过或某一恒定温度下，且过程在下面的步骤顺序进行：（A）同时加热若干反应容器和维护在预定温度下将反应容器的恒定容器的加热步骤; （B）把一个样品中的每一个被加热的反应容器中，在规定的温度的两相溶液的维护的样品加热步骤; （C）搅拌样品的反应的步骤并已被加热到预定的，以便获得均匀的溶液的温度，所有这些都被保持在预定的时间周期; （D）冷却该均匀溶液而不在预定的时间段已经过去之后，以获得对反应容器内的两相溶液冷却反应容器的冷却步骤。 。根据本发明，用于制备其中的两相溶液通过温度转换的相位状态的变化通过许多方法进行反应，worin化学过程的方法，可以对多个样本的相同条件下在一个方法中进行 装置，以及以设备为实现此，可以提供。