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1.发明公开METHOD FOR TREATING DISEASES USING HSP90-INHIBITING AGENTS IN COMBINATION WITH ANTIMITOTICS 有权方法与HSP90消炎药疾病杂志与抗有丝分裂结合物处理
公开(公告)号：EP1628667A4
公开(公告)日：2007-04-04
申请号：EP04753672
申请日：2004-05-28
发明人： JOHNSON ROBERT JR , ZHOU YIQING , MUELLER THOMAS
IPC分类号： A61K45/06 , A61K31/427 , A61K31/535
CPC分类号： A61K45/06 , A61K31/427
摘要： The present invention provides a method for treating cancer. The method involves the administration of an HSP90 inhibitor and an antimitotic, where the combined administration provides a synergistic effect. In one aspect of the invention, a method of treating cancer is provided where a subject is treated with a dose of an HSP90 inhibitor in one step and a dose of an antimitotic in another step. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an HSP90 inhibitor and subsequently treated with a dose of an antimitotic. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an antimitotic and subsequently treated with a dose of an HSP90 inhibitor.
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2.发明公开METHOD FOR TREATING DISEASES USING HSP90-INHIBITING AGENTS IN COMBINATION WITH ANTIMETABOLITES 有权HSP90抑制剂联合抗变态反应药治疗疾病的方法
公开(公告)号：EP1631267A4
公开(公告)日：2006-07-12
申请号：EP04776158
申请日：2004-05-28
发明人： JOHNSON ROBERT JR , ZHOU YIQING , MUELLER THOMAS
IPC分类号： A61K20060101 , A61K31/33 , A61K31/395 , A61K31/505 , A61K31/513 , A61K31/522 , A61K31/525 , A61K31/7072 , A61K45/06
CPC分类号： A61K31/513 , A61K31/395 , A61K31/522 , A61K31/525 , A61K45/06 , A61K2300/00
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3.发明公开METHOD FOR TREATING DISEASES USING HSP90-INHIBITING AGENTS IN COMBINATION WITH ENZYME INHIBITORS 审中-公开方法与HSP90消炎药疾病的结合酶抑制剂治疗
公开(公告)号：EP1628623A4
公开(公告)日：2008-11-26
申请号：EP04753673
申请日：2004-05-28
发明人： JOHNSON ROBERT JR , ZHOU YIQING , MUELLER THOMAS
IPC分类号： A61K31/165 , A61K20060101 , A61K31/19 , A61K31/33 , A61K31/395 , A61K31/517 , A61P35/00
CPC分类号： A61K31/165 , A61K31/395 , A61K31/517
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4.发明公开METHOD FOR TREATING DISEASES USING HSP90-INHIBITING AGENTS IN COMBINATION WITH PLATINUM COORDINATION COMPLEXES 审中-公开法疾病与合用HSP90消炎药与铂配合物的治疗
公开(公告)号：EP1628657A4
公开(公告)日：2007-04-25
申请号：EP04753658
申请日：2004-05-28
发明人： JOHNSON ROBERT JR , ZHOU YIQING , MUELLER THOMAS
IPC分类号： A61K33/24 , A61K20060101 , A61K31/28 , A61K31/33 , A61K45/06
CPC分类号： A61K33/24 , A61K31/28 , A61K45/06 , A61K2300/00
摘要： The present invention provides a method for treating cancer. The method involves the administration of an HSP90 inhibitor and a platinum coordination complex, where the combined administration provides a synergistic effect. In one aspect of the invention, a method of treating cancer is provided where a subject is treated with a dose of an HSP90 inhibitor in one step and a dose of a platinum coordination complex in another step. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an HSP90 inhibitor and subsequently treated with a dose of a platinum coordination complex. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of a platinum coordination complex and subsequently treated with a dose of an HSP90 inhibitor.
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