公开(公告)号：EP4426278A1

公开(公告)日：2024-09-11

申请号：EP22889566.0

申请日：2022-10-03

Applicant: TyrNovo Ltd.

Inventor： REUVENI, Hadas

IPC: A61K31/165 ,  A61P35/00 ,  C07C327/44

CPC classification number: A61P35/00 ,  A61K9/08 ,  A61K47/40 ,  A61K9/0019 ,  A61K31/165 ,  A61K45/06 ,  C07C327/44

公开(公告)号：EP4406531A1

公开(公告)日：2024-07-31

申请号：EP23305087.1

申请日：2023-01-24

Applicant: PK MED

Inventor： The designation of the inventor has not yet been filed

IPC: A61K9/00 ,  A61K31/165 ,  A61K31/445 ,  A61K45/06 ,  A61K47/34 ,  A61P19/02 ,  A61P19/06 ,  A61K9/16

CPC classification number: A61K9/0024 ,  A61K9/1647 ,  A61K9/0019 ,  A61K31/165 ,  A61K31/445 ,  A61P19/02 ,  A61P19/06 ,  A61K45/06 ,  A61K47/34

Abstract: The present invention relates to a pharmaceutical composition suitable for an intra-articular injection comprising an anesthetic agent and a controlled release dosage form comprising colchicine. It further relates to a pharmaceutical composition under the form of a powder comprising an anesthetic agent and controlled release dosage form comprising colchicine, wherein said controlled release dosage form comprising colchicine are under the form of microparticles. It further relates to a pharmaceutical composition under the form of a powder comprising an anesthetic agent and controlled release dosage form comprising colchicine, wherein said controlled release dosage form comprising colchicine are under the form of microparticles, to a kit and to the use of said pharmaceutical compositions or kit in the treatment of crystal-associated and non-crystal associated acute inflammatory arthritis, in particular a crystal-associated arthropathy or flares or acute forms of tendinitis and capsulitis by intra-articular injection into a joint of said pharmaceutical composition, and in providing pain relief immediately and all over the treatment.

公开(公告)号：EP4368618A1

公开(公告)日：2024-05-15

申请号：EP22836740.5

申请日：2022-06-24

Applicant: Betta Pharmaceuticals Co., Ltd

Inventor： FU, Bang ,  LI, Yinlong ,  REN, Wei ,  SHEN, Qichao ,  DU, Guolong ,  ZHOU, Xiaojun ,  SUN, Yun ,  ZHOU, Yuzhen ,  SUN, Xiao ,  CAI, Weidong ,  LIU, Xiangyong ,  DING, Lieming ,  WANG, Jiabing

IPC: C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D403/12 ,  C07D409/14 ,  A61K31/165 ,  A61K31/4192 ,  A61P35/00

CPC classification number: A61K31/165 ,  A61K31/4192 ,  A61P35/00 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D401/04 ,  C07D409/14 ,  C07D413/14

Abstract: A compound of formula I and a use thereof as an MALT1 inhibitor, and a pharmaceutical composition containing the compound. The compound can be used to treat diseases or disorders such as cancer.

公开(公告)号：EP4366716A1

公开(公告)日：2024-05-15

申请号：EP22838610.8

申请日：2022-07-08

Applicant: Klotho Therapeutics, Inc.

Inventor： PLANTE, James ,  RAMAGE, William ,  BISHOP, Michael, Joseph ,  KASAHARA, Noriyuki ,  TSENKINA, Yanina ,  CRUNK, Amanda

IPC: A61K31/165 ,  C07C323/62 ,  A61P35/00

CPC classification number: A61P35/00 ,  A61K31/165 ,  C07C323/60 ,  C07C323/52 ,  A61K31/195 ,  A61K33/243 ,  A61K31/445 ,  A61K31/221 ,  A61K31/40 ,  A61K31/397 ,  A61K31/555

公开(公告)号：EP4360619A1

公开(公告)日：2024-05-01

申请号：EP22306613.5

申请日：2022-10-25

Applicant: PK MED

Inventor： The designation of the inventor has not yet been filed

IPC: A61K9/00 ,  A61K31/165 ,  A61K31/445 ,  A61K47/34 ,  A61P29/00 ,  A61P19/02 ,  A61K9/10 ,  A61K9/16

CPC classification number: A61K9/1647 ,  A61K9/0019 ,  A61K31/165 ,  A61K31/445 ,  A61P29/00 ,  A61P19/02 ,  A61K45/06 ,  A61K31/167

Abstract: The present invention relates to a pharmaceutical composition suitable for an intra-articular injection comprising an anesthetic agent and a controlled release dosage form comprising colchicine. It further relates to a pharmaceutical composition under the form of a powder comprising an anesthetic agent and controlled release dosage form comprising colchicine, wherein said controlled release dosage form comprising colchicine are under the form of microparticles. It further relates to a pharmaceutical composition under the form of a powder comprising an anesthetic agent and controlled release dosage form comprising colchicine, wherein said controlled release dosage form comprising colchicine are under the form of microparticles, to a kit and to the use of said pharmaceutical compositions or kit in the treatment of crystal-associated and non-crystal associated acute inflammatory arthritis, in particular a crystal-associated arthropathy or flares or acute forms of tendinitis and capsulitis by intra-articular injection into a joint of said pharmaceutical composition, and in providing pain relief immediately and all over the treatment.

公开(公告)号：EP3431081B1

公开(公告)日：2024-05-01

申请号：EP17789807.9

申请日：2017-04-07

IPC: A61K8/49 ,  A61K8/42 ,  A61K8/02 ,  A61K31/164 ,  A61K31/165 ,  A61K31/404 ,  A61K31/4164 ,  A61K9/06 ,  A61K9/70 ,  A61Q19/00 ,  A61P17/00

CPC classification number: A61K8/49 ,  A61Q19/00 ,  A61K9/06 ,  A61K8/02 ,  A61K9/70 ,  A61K31/164 ,  A61K31/165 ,  A61K31/404 ,  A61K31/4164 ,  A61K8/42 ,  A61P17/00

公开(公告)号：EP4356907A1

公开(公告)日：2024-04-24

申请号：EP23219005.8

申请日：2015-09-04

Applicant: LobSor Pharmaceuticals Aktiebolag

Inventor： BOLSÖY, Roger

IPC: A61K31/198 ,  A61K31/277 ,  A61K31/165 ,  A61K45/06 ,  A61K9/06 ,  A61K47/38 ,  A61P25/16

CPC classification number: A61K9/06 ,  A61K31/277 ,  A61K9/0019 ,  A61K47/38 ,  A61K9/0024 ,  A61K45/06 ,  A61K31/198 ,  A61P25/16 ,  A61P25/28 ,  A61K31/165

Abstract: A pharmaceutical gel composition for intra-intestinal administration comprises (i) a dopamine replacement agents, (ii) a dopamine decarboxylase inhibitor (DDI), and (iii) a COMT inhibitor.

公开(公告)号：EP4076380B1

公开(公告)日：2024-04-24

申请号：EP20780760.3

申请日：2020-10-02

IPC: A61K9/00 ,  A61K31/165 ,  A61P25/24

CPC classification number: A61P25/24 ,  A61K31/165 ,  A61K9/006

公开(公告)号：EP3398948A3

公开(公告)日：2018-12-05

申请号：EP18177058.7

申请日：2015-08-21

Applicant: Janus Biotherapeutics, Inc.

Inventor： LIPFORD, Grayson B ,  ZEPP, Charles M

IPC: C07D475/02 ,  C07D475/06 ,  C07D475/00 ,  C07D475/08 ,  A61K31/519 ,  A61P19/00 ,  A61P17/00 ,  A61P3/00

CPC classification number: C07D475/08 ,  A61K31/165 ,  A61K31/496 ,  A61K31/519 ,  A61K31/5375 ,  C07D475/00 ,  C07D475/02 ,  C07D475/06

Abstract: Compounds as immune system modulators bearing a pteridine core are described. A pharmaceutical composition comprising the same, methods of making the same, and a method for treating or preventing autoimmunity disease using the same are described.

公开(公告)号：EP2349344B1

公开(公告)日：2018-12-05

申请号：EP09760548.9

申请日：2009-10-20

Applicant: Incanthera Limited

Inventor： FALCONER, Robert, Andrew ,  GILL, Jason ,  ATKINSON, Jennifer ,  LOADMAN, Paul ,  BIBBY, Michael ,  PATTERSON, Laurence

IPC: A61K47/55 ,  A61K47/60 ,  A61K47/65 ,  A61K31/165 ,  A61K31/135

CPC classification number: A61K47/64 ,  A61K31/135 ,  A61K31/165 ,  A61K47/55 ,  A61K47/556 ,  A61K47/60 ,  A61K47/65 ,  C07K7/06

Abstract: The present invention relates to prodrugs of vascular disrupting agents comprising a vascular disrupting agent (VDA) associated with a MMP proteolytic cleavage site and to the use of such prodrugs in the targeted treatment of cancer.