摘要:
6-Chloro-3-pyridylmethylpropylamine derivatives of the general formula (I), and acid addition salts thereof wherein W is 3,5-bistrifluoromethylphenyl, 4-trifluoro- methoxyphenyl, 3-chloro-5-fluorophenyl, 2,2-difluoro-1,3- benzodioxol-5-yl, or the like.
摘要:
An N-(heterocycle-methyl)alkylamine derivative which is one represented by the following general formula (I) or an acid addition salt thereof. [In the formula, R1 represents a heterocycle containing at least one nitrogen atom as a heteroatom and optionally having one or more substituents on the ring; R2 represents hydrogen, etc.; R3 represents C¿1-5? alkyl, etc. and R?4¿ represents C¿1-5? alkyl, etc., provided that when R?4¿ is C¿1-5? alkyl or C1-5 halogenoalkyl, then a carbon atom of R?3¿ may be bonded to a carbon atom of R4 to form a ring structure; m is an integer of 1 to 3; and R5 represents, e.g., cycloalkyl represented by the following formula (III) (wherein Y and Z each represents hydrogen, etc.; p is an integer of 2 to 5; and the groups represented by CYZ may be the same or different) provided that when m is 1 and R4 is hydrogen, then R5 is cycloalkyl represented by the formula (III).]
摘要:
N-Heterocyclic methylpropylamine derivatives of general formula (I) and acid-addition salts thereof, wherein R is hydrogen, halogeno, alkyl, alkenyl, haloalkyl, alkoxyl, haloalkoxyl, hydroxyl, cyano, nitro, optionally substituted phenyl, or phenoxy; n is an integer of 0 to 5; R is an optionally substituted heterocycle having at least one nitrogen atom as the heteroatom; and R is hydrogen or C1 to C5 alkyl.