公开(公告)号：EP3400941A1

公开(公告)日：2018-11-14

申请号：EP17735999.9

申请日：2017-01-05

申请人： Keio University ,  Tokyo Institute of Technology

发明人： SAYA, Hideyuki ,  NAGANO, Osamu ,  TSUCHIHASHI, Kenji ,  SUINA, Kentaro ,  NISHIYAMA, Nobuhiro ,  TAKEMOTO, Hiroyasu ,  NOMOTO, Takahiro ,  MATSUI, Makoto ,  TOMODA, Keishiro ,  YAMADA, Naoki ,  NISHIMORI, Tsukasa

IPC分类号： A61K31/4402 ,  A61K9/08 ,  A61K31/655 ,  A61K31/77 ,  A61K47/34 ,  A61K47/50 ,  A61P35/00

CPC分类号： A61K9/08 ,  A61K31/4402 ,  A61K31/655 ,  A61K31/77 ,  A61K47/34 ,  A61K47/50

摘要： The present invention is directed to provide antitumor agent including water-soluble sulfasalazine as an active ingredient. Antitumor agents were obtained with, as the water-soluble sulfasalazine, a PEG-modified sulfasalazine represented by the following formula:

wherein an average value of n is 4 or larger and 1136 or smaller.