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1.发明公开Beta-O/S/N fatty acid based compounds as antibacterial and antiprotozoal agents 审中-公开Verbindungen auf beta-O / S / N-Fettsäurebasisals Antibakterium-和Antiprotozoenmittel
公开(公告)号：EP2601941A1
公开(公告)日：2013-06-12
申请号：EP11192121.9
申请日：2011-12-06
IPC分类号： A61K31/047 , A61K31/165 , A61K31/192 , A61K31/216 , A61P31/04
CPC分类号： C07D229/02 , A01N31/02 , A01N37/18 , A01N37/36 , A01N43/62 , A61K31/047 , A61K31/165 , A61K31/201 , A61K31/222 , A61K31/231 , C07C33/26 , C07C57/42 , C07C59/48 , C07C235/34 , Y02A50/409 , Y02A50/411 , Y02A50/473 , Y02A50/478
摘要： The present invention relates to beta-O/S/N fatty acids and derivatives thereof, in particular the compounds of formula (I) as described and defined herein, and their pharmaceutical use, including their use in the treatment or prevention of bacterial as well as protozoan infections, in particular the treatment or prevention of infections with Gram-positive and/or Gram-negative bacteria and infectious diseases caused by and/or related to Gram-positive and/or Gram-negative bacteria. The invention further relates to the use of these compounds for preventing or eliminating biofilms.
摘要翻译： 本发明涉及β-O / S / N脂肪酸及其衍生物，特别是本文所述和定义的式（I）化合物及其药物用途，包括其用于治疗或预防细菌的用途 作为原生动物感染，特别是治疗或预防由革兰氏阳性和/或革兰氏阴性细菌引起和/或相关的革兰氏阳性和/或革兰氏阴性细菌和感染性疾病的感染。 本发明还涉及这些化合物用于预防或消除生物膜的用途。
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2.发明公开Beta-O/S/N fatty acid based compounds as antibacterial and antiprotozoal agents 审中-公开对β-O化合物/ S / N-基于脂肪酸如Antibakterium-和抗原虫
公开(公告)号：EP2898880A1
公开(公告)日：2015-07-29
申请号：EP14198890.7
申请日：2012-12-06
IPC分类号： A61K31/047 , A61K31/165 , A61K31/192 , A61K31/216 , A61P31/04
CPC分类号： C07D229/02 , A01N31/02 , A01N37/18 , A01N37/36 , A01N43/62 , A61K31/047 , A61K31/165 , A61K31/201 , A61K31/222 , A61K31/231 , C07C33/26 , C07C57/42 , C07C59/48 , C07C235/34 , Y02A50/409 , Y02A50/411 , Y02A50/473 , Y02A50/478
摘要： The present invention relates to beta-O/S/N fatty acids and derivatives thereof, in particular the compounds of formula (I) as described and defined herein, and their pharmaceutical use, including their use in the treatment or prevention of bacterial as well as protozoan infections, in particular the treatment or prevention of infections with Gram-positive and/or Gram-negative bacteria and infectious diseases caused by and/or related to Gram-positive and/or Gram-negative bacteria. The invention further relates to the use of these compounds for preventing or eliminating biofilms.
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3.发明公开Thiirane and michael acceptor compounds and their medical use 审中-公开Thiiran-和Michael-Akzeptor-Verbindungen und deren medizinische Verwendung
公开(公告)号：EP2607361A1
公开(公告)日：2013-06-26
申请号：EP11194584.6
申请日：2011-12-20
IPC分类号： C07D331/02 , A61P31/04
CPC分类号： C07D331/02
摘要： The present invention relates to thiirane or Michael acceptor compounds, including the compounds of formula (I) as described and defined herein, and pharmaceutical compositions comprising these compounds, as well as their medical use, particularly their use in the treatment or prevention of a bacterial infection, including, e.g., an infection with multidrug-resistant Staphylococcus aureus.
摘要翻译： 本发明涉及包括本文所述和定义的式（I）化合物的硫烷或迈克尔受体化合物，以及包含这些化合物的药物组合物及其医疗用途，特别是其在治疗或预防细菌中的用途 感染，包括例如感染多药耐药金黄色葡萄球菌。
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公开(公告)号：EP4261542A1
公开(公告)日：2023-10-18
申请号：EP22167551.5
申请日：2022-04-11
IPC分类号： G01N33/82 , G01N33/543
摘要： The present invention relates to in vitro methods for determining the vitamin status of a subject, in particular health related vitamins, such as B2, B6, B12 and/or D3. The present invention further relates to a kit and an immunographic device for in vitro determining the vitamin status of a subject.
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