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1.发明公开
公开(公告)号：EP2349305A4
公开(公告)日：2012-08-22
申请号：EP09825326
申请日：2009-11-04
申请人： METAPROTEOMICS LLC
IPC分类号： A61K36/906 , A61K36/185 , A61K36/22 , A61K36/27 , A61K36/33 , A61K36/35 , A61K36/48 , A61K36/61 , A61K36/71 , A61K36/73 , A61K36/738 , A61K36/82 , A61K36/87 , A61K36/9066 , A61K36/9068 , A61K38/01
CPC分类号： A61K36/9068 , A61K36/185 , A61K36/22 , A61K36/27 , A61K36/33 , A61K36/35 , A61K36/48 , A61K36/61 , A61K36/71 , A61K36/73 , A61K36/738 , A61K36/82 , A61K36/87 , A61K36/9066 , A61K38/018
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2.发明公开SUBSTITUTED 1,3-CYCLOPENTADIONE ATTENUATED ENDOTHELIAL INFLAMMATION AND ENDOTHELIAL-MONOCYTE INTERACTIONS 审中-公开取代的1,3-环戊二烯增强的内皮细胞激活和内皮单核细胞相互作用
公开(公告)号：EP2268600A4
公开(公告)日：2012-03-21
申请号：EP09728126
申请日：2009-04-02
申请人： METAPROTEOMICS LLC
发明人： LAMB JOSEPH , KONDA VEERA , DESAI ANU , TRIPP MATTHEW L , DARLAND GARY , BLAND JEFFREY S , EMMA DENNIS A
IPC分类号： A61K31/122 , A61P9/00 , A61P43/00
CPC分类号： C07C49/707 , C07B2200/07 , C07C2601/10
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3.发明公开NOVEL MITOCHONDRIAL UNCOUPLING METHODS AND COMPOSITIONS FOR ENHANCING ADIPOCYTE THERMOGENESIS 审中-公开新的线粒体在脂肪细胞中解耦方法和组合物改善的热
公开(公告)号：EP2348868A4
公开(公告)日：2013-06-12
申请号：EP09822521
申请日：2009-10-20
申请人： METAPROTEOMICS LLC
CPC分类号： A61K31/05 , A61K36/00 , A61K2300/00
摘要： Disclosed are methods, compounds, and compositions comprising botanically based drugs, medical foods, and dietary supplements for the prevention and treatment of metabolic disorders, in particular obesity, weight gain, insulin resistance syndromes, diabetes, fasting hyperlipidemia and osteoarthritis. More specifically, the invention relates to pharmaceutical therapeutic methods and compositions utilizing phytochemicals, natural plant extracts and combinations to modify adipocyte physiology to enhance thermogenesis and modify cytokine secretion.
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公开(公告)号：EP1993528A4
公开(公告)日：2010-07-28
申请号：EP07717798
申请日：2007-01-04
申请人： METAPROTEOMICS LLC
发明人： TRIPP MATTHEW L , BLAND JEFFREY S , LERMAN ROBERT , HALL AMY , KONDA VEERA , DESAI ANU
CPC分类号： A61K36/185 , A61K31/12 , A61K36/53 , A61K45/06 , A61K2300/00
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5.发明公开SYNERGISTIC ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS USING CURCUMINOIDS OR METHYLXANTHINES 有权协同抗炎药物组合物及相关方法使用或姜黄色素，甲基黄嘌呤
公开(公告)号：EP1718312A4
公开(公告)日：2009-09-30
申请号：EP05723839
申请日：2005-02-26
申请人： METAPROTEOMICS LLC
发明人： BABISH JOHN G , TRIPP MATTHEW L , BLAND JEFFREY S
IPC分类号： A61K31/557 , A61K31/12 , A61K31/19 , A61K31/522 , A61K36/185 , A61K36/9066 , A61K45/06
CPC分类号： A61K31/522 , A61K31/12 , A61K31/19 , A61K36/185 , A61K36/9066 , A61K45/06 , A61K2300/00
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公开(公告)号：EP2152684A4
公开(公告)日：2011-05-18
申请号：EP08729724
申请日：2008-02-13
申请人： METAPROTEOMICS LLC
发明人： TRIPP MATTHEW L , KONDA VEERA , HALL AMY , DESAI ANU , BLAND JEFFREY S , MINICH DEANNA
IPC分类号： A61K31/121 , A61K31/00 , A61K31/122 , A61K31/365 , A61K33/30 , A61P39/02 , A61P39/04 , A61P43/00
CPC分类号： C07D309/24 , A61K31/00 , A61K31/121 , A61K31/122 , A61K31/365 , A61K33/30 , C07C49/255 , C07C49/707 , C07C49/743 , A61K2300/00
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7.发明公开SUBSTITUTED 1,3-CYCLOPENTADIONE MULTI-TARGET PROTEIN KINASE MODULATORS OF CANCER, ANGIOGENESIS AND THE INFLAMMATORY PATHWAYS ASSOCIATED THEREWITH 审中-公开FOR相关的炎症，肿瘤，血管生成和量级的取代的1,3-环戊二酮-MULTI-靶蛋白激酶调节剂
公开(公告)号：EP2229178A4
公开(公告)日：2011-03-09
申请号：EP08859091
申请日：2008-12-10
申请人： METAPROTEOMICS LLC
发明人： TRIPP MATTHEW L , BABISH JOHN G , BLAND JEFFREY S , KONDA VEERA , DESAI ANU , DARLAND GARY , CARROLL BRIAN , TRAUB JAMES , PACIORETTY LINDA M , EMMA DENNIS A
CPC分类号： A61K31/12 , A61K45/06 , A61K2300/00
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8.发明公开
公开(公告)号：EP1718313A4
公开(公告)日：2007-07-25
申请号：EP05723895
申请日：2005-02-26
申请人： METAPROTEOMICS LLC
发明人： BABISH JOHN G , TRIPP MATTHEW L , BLAND JEFFREY S
IPC分类号： A61K31/557 , A61K31/12 , A61K31/19 , A61K36/18 , A61K36/185
CPC分类号： A61K36/185 , A61K31/12 , A61K31/19 , A61K31/557 , A61K36/12 , A61K2300/00
摘要： The invention provides a composition comprising a reduced isoalpha acid (RIAA) and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of about 3:1 to about 1:10. The invention also provides a method of reducing inflammation by administering a composition comprising a reduced isoalpha acid (RIAA) and isoalpha acid (IAA) isolated from hops, wherein the RIAA and IAA are in a ratio of, about 3:1 to about 1:10.
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9.发明公开
公开(公告)号：EP1626731A4
公开(公告)日：2006-08-02
申请号：EP04809400
申请日：2004-05-21
申请人： METAPROTEOMICS LLC
发明人： BABISH JOHN G , TRIPP MATTHEW L , HOWELL TERRENCE , BLAND JEFFREY S , DARLAND GARY , LERMAN ROBERT , LUKACZER DANIEL O
IPC分类号： A61K20060101 , A61K31/00 , A61K31/12 , A61K31/557 , A61K36/185 , A61K45/06
CPC分类号： A61K31/00 , A61K31/192 , A61K31/365 , A61K31/405 , A61K31/415 , A61K36/185 , A61K45/06 , A61K2300/00
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10.发明公开COMPOSITIONS THAT TREAT OR INHIBIT PATHOLOGICAL CONDITIONS ASSOCIATED WITH INFLAMMATORY RESPONSE 审中-公开用于治疗或抑制病理组合物在与炎症反应CONNECTION
公开(公告)号：EP1558271A4
公开(公告)日：2006-01-11
申请号：EP03777751
申请日：2003-10-20
申请人： METAPROTEOMICS LLC
发明人： TRIPP MATTHEW L , BABISH JOHN G , BLAND JEFFREY S , DARLAND GARY , LERMAN ROBERT , LUKACZER DANIEL O , LISKA DEANN J , HOWELL TERRENCE
IPC分类号： A61K20060101 , A61K31/122 , A61K31/19 , A61K31/215 , A61K35/78
CPC分类号： A61K36/185 , A61K31/122 , A61K36/53 , A61K2300/00
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