公开(公告)号：EP4434358A1

公开(公告)日：2024-09-25

申请号：EP22895594.4

申请日：2022-11-15

Applicant: House Foods Group Inc.

Inventor： IWASAKI Yusaku

IPC: A23L33/10 ,  A23L33/105 ,  A23L33/12 ,  A61K31/122 ,  A61K31/192 ,  A61K31/201 ,  A61P1/14 ,  A61P25/02 ,  A61P43/00 ,  C07C50/16 ,  C07C66/02

CPC classification number: A23L33/10 ,  A23L33/105 ,  A23L33/12 ,  A61K31/122 ,  A61K31/201 ,  A61K31/192 ,  A61P1/14 ,  A61P25/02 ,  A61P43/00 ,  C07C50/16 ,  C07C66/02

Abstract: The purpose of the present invention is to newly discover a transient receptor potential ankyrin 1 (TRPA1) agonist that exhibits an action for increasing the amount of food ingested, to provide a novel agonist of TRPA1, or to provide a novel active ingredient that exhibits an action for increasing the amount of food ingested or an action for improving anorexia. A compound having a specific fatty acid or a specific anthraquinone structure has an effect for activating TRPA1 and can be used as an active ingredient for increasing the amount of food ingested and/or improving anorexia.

公开(公告)号：EP3435993B1

公开(公告)日：2024-09-25

申请号：EP17716149.4

申请日：2017-04-03

IPC: A61K31/16 ,  A61P27/00 ,  A61P29/00 ,  A61K31/165 ,  A61K31/19 ,  A61K31/192 ,  A61K31/22 ,  A61K31/341 ,  A61K31/351 ,  A61K31/40 ,  A61K31/41 ,  A61K31/4196 ,  A61K31/421 ,  A61K31/5375

CPC classification number: A61K31/16 ,  A61K31/165 ,  A61K31/19 ,  A61K31/192 ,  A61K31/22 ,  A61K31/341 ,  A61K31/351 ,  A61K31/40 ,  A61K31/41 ,  A61K31/4196 ,  A61K31/421 ,  A61K31/5375 ,  A61P27/00 ,  A61P29/00

公开(公告)号：EP3452032B1

公开(公告)日：2024-09-04

申请号：EP17719772.0

申请日：2017-04-07

IPC: A61K31/192 ,  A61K31/167 ,  A61K31/232 ,  A61K31/235 ,  A61K31/25 ,  A61K31/353 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/4155 ,  A61K31/426 ,  A61K31/44 ,  A61K31/4436 ,  A61K31/498 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/55 ,  A61K31/551 ,  A61K31/553 ,  A61K31/573 ,  A61K31/69 ,  A61K31/695 ,  A61K33/24 ,  A61K33/36 ,  A61K45/06 ,  G01N33/48 ,  A61P35/00 ,  A61P35/02 ,  A61P35/04 ,  A61P43/00

CPC classification number: A61K45/06 ,  A61K31/167 ,  A61K31/192 ,  A61K31/232 ,  A61K31/235 ,  A61K31/25 ,  A61K31/353 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/4155 ,  A61K31/426 ,  A61K31/44 ,  A61K31/4436 ,  A61K31/498 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/55 ,  A61K31/551 ,  A61K31/553 ,  A61K31/573 ,  A61K31/69 ,  A61K31/695 ,  A61K31/704 ,  A61K31/706 ,  A61K31/7068 ,  A61K33/24 ,  A61K33/36 ,  G01N33/48 ,  A61P35/00 ,  A61P35/02 ,  A61P35/04 ,  A61P43/00

公开(公告)号：EP4415702A1

公开(公告)日：2024-08-21

申请号：EP22881706.0

申请日：2022-10-12

Applicant: New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special Surgery

Inventor： BARRAT, Franck ,  IVASHKIV, Lionel

IPC: A61K31/20 ,  A61K8/36 ,  A61P31/12 ,  A61P31/14

CPC classification number: A61P31/12 ,  A61P31/14 ,  A61K31/7072 ,  A61K31/365 ,  A61K31/192 ,  A61K31/405 ,  A61K31/501 ,  A61K45/06

公开(公告)号：EP4374861A3

公开(公告)日：2024-08-07

申请号：EP23203862.0

申请日：2016-11-16

Applicant: MedinCell S.A.

Inventor： GAUDRIAULT, Georges ,  GRIZOT, Sylvestre ,  HURTIG, Mark ,  SHIVE, Matthew

IPC: A61K9/00 ,  A61K47/34 ,  A61K9/08 ,  A61K31/415 ,  A61P19/02 ,  A61K31/12 ,  A61K31/165 ,  A61K31/167 ,  A61K31/18 ,  A61K31/192 ,  A61K31/365 ,  A61K31/196 ,  A61K31/42 ,  A61K31/444 ,  A61K31/445 ,  A61K31/5415 ,  A61K31/621 ,  A61P3/02

CPC classification number: A61K9/0019 ,  A61K9/0024 ,  A61K47/34 ,  A61K9/08 ,  A61K31/196 ,  A61K31/445 ,  A61K31/365 ,  A61K31/12 ,  A61K31/621 ,  A61K31/444 ,  A61K31/5415 ,  A61K31/4152 ,  A61K31/42 ,  A61K31/167 ,  A61K31/165 ,  A61K31/18 ,  A61K31/192

Abstract: A method of targeting to the synovial tissue biodegradable drug delivery compositions or morselizing biodegradable drug delivery compositions are described. The biodegradable drug composition comprises a triblock copolymer containing a polyester and a polyethylene glycol and a diblock copolymer containing a polyester and an end-capped polyethylene glycol, as well as at least one pharmaceutically active principle is disclosed.

公开(公告)号：EP4406937A1

公开(公告)日：2024-07-31

申请号：EP22871956.3

申请日：2022-09-20

Applicant: Hangzhou Phecdamed Co., Ltd.

Inventor： XIA, Hongguang ,  FAN, Mengyang ,  CEN, Xufeng ,  XU, Xiaoyan ,  WU, Ronghai ,  LIU, Dong ,  TIAN, Zhen

IPC: C07C323/52 ,  C07C381/10 ,  C07D305/08 ,  C07D285/10 ,  C07D285/16 ,  C07D249/08 ,  C07D257/04 ,  C07D333/34 ,  A61K31/192 ,  A61K31/337 ,  A61K31/381 ,  A61K31/265 ,  A61K31/222 ,  A61K31/4196 ,  A61K31/41 ,  A61K31/549 ,  A61K31/433 ,  A61P43/00

CPC classification number: A61K31/222 ,  A61K31/192 ,  A61K31/337 ,  A61K31/265 ,  A61K31/381 ,  A61K31/41 ,  A61K31/433 ,  A61K31/4196 ,  A61K31/549 ,  A61P43/00 ,  C07C323/52 ,  C07C381/10 ,  C07D249/08 ,  C07D257/04 ,  C07D285/10 ,  C07D285/16 ,  C07D305/08 ,  C07D333/34

Abstract: The present application discloses a small-molecule compound having a naphthalenethiol ether structure, and a use thereof. Disclosed in the present application are a compound having a structure represented by general formula (I), a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, a pharmaceutical composition containing the same, and a use thereof in the preparation of mitophagy inducer drugs. In the present application, the structure of the compound having the structure represented by general formula (I) is shown below. The compound and the pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, or the pharmaceutical composition provided in the present application can enhance the ability to induce mitophagy.

公开(公告)号：EP3570825B1

公开(公告)日：2024-07-31

申请号：EP18741911.4

申请日：2018-01-09

IPC: A61K31/122 ,  A61K31/192 ,  A61K31/196 ,  A61K31/216 ,  A61K31/222 ,  A61K31/606 ,  A61P1/00 ,  A61P1/06

CPC classification number: A61K31/216 ,  A61P1/00 ,  A61K31/196 ,  A61K31/122 ,  A61K31/222 ,  A61K31/192 ,  A61K31/606 ,  A61P1/06

公开(公告)号：EP3937923B1

公开(公告)日：2024-07-24

申请号：EP20715434.5

申请日：2020-03-11

IPC: A61K31/192 ,  A61K31/203 ,  A61K31/47 ,  A61K31/495 ,  A61P25/28 ,  C07D215/06 ,  C07C65/28 ,  C07C63/74

CPC classification number: A61K31/192 ,  A61K31/203 ,  A61K31/47 ,  A61K31/495 ,  A61P25/28 ,  C07D241/42 ,  C07D213/79 ,  C07C63/74 ,  C07C65/28

公开(公告)号：EP3664795B1

公开(公告)日：2024-06-19

申请号：EP18844547.2

申请日：2018-08-09

IPC: A61K31/352 ,  A61K31/05 ,  A61K31/192 ,  A61K36/185 ,  A61P29/00 ,  A61P1/02 ,  A61P43/00 ,  C07D311/80

CPC classification number: A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61P1/02 ,  A61K36/185 ,  A61P29/00 ,  A61P41/00

公开(公告)号：EP3527205B1

公开(公告)日：2024-06-12

申请号：EP17860262.9

申请日：2017-10-11

IPC: A61K9/70 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/38 ,  A61K31/192 ,  A61P29/00

CPC classification number: A61P29/00 ,  A61K31/192 ,  A61K9/7053 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/38