摘要:
There is provided a means for sterilizing lactoferrin at a high temperature in a short time while maintaining the activity of the lactoferrin. The present technology provides a method for producing a lactoferrin-containing aqueous solution, including a sterilization step of heat-sterilizing a lactoferrin-containing aqueous solution, in which the total mass content of proteins other than lactoferrin is 1/12 or less of the mass content of lactoferrin, at a temperature of 100°C or more. The present technology also provides a lactoferrin-containing aqueous solution in which the total mass content of proteins other than lactoferrin is 1/12 or less of the mass content of lactoferrin, and which does not contain living bacteria.
摘要:
It is aimed to provide a spout member and a packaging bag using the spout member which have excellent handling property and hygiene management performance at the time of supplying water or the like from the outside before and during use such as administration of water and medicine, in which a closure means for freely opening and closing an aperture formed by cutting off parts of peripheral portions of sealed film pieces is protected from a contained content at the time of storage or transportation and which have excellent protecting property even when an inner pressure acts in the packaging bag, excellent contamination preventing property until a spout is opened and excellent contamination preventing property and handling property after opening. In a packaging bag formed by sealing peripheral portions of a plurality of film pieces and including an inlet portion and a spout portion at the peripheral portions, the inlet portion is opened as an inlet port by cutting off parts of the peripheral portions of the sealed film pieces to form an aperture by an unsealed portion, at least two holes are formed at the opposite sides of a part which becomes the inlet port at the peripheral portions near the inlet portion, and the holes serve as a suspension means for enabling the packaging bag to be suspended and a finger holding means. An openable and closable closure means including first and second members engageable with each other is formed by bonding an upper part of a first base member including the first member and an upper part of a second base member including the second member respectively to inner sides of the film pieces forming the aperture and facing each other, and a bottom end portion of one base member is formed to be longer than that of the other base member and bonded to the other film piece opposite thereto by an easily peelable seal, thereby forming an easily peelable portion which is peeled open to open the aperture at the time of opening. A spout member is provided with a spout portion including a base portion and a cylindrical portion projecting from the base portion, a sealing portion for sealing a tip portion of the cylindrical portion via a tearable weakened portion, and a cap portion. The weakened portion is torn by turning the cap portion to separate the sealing portion and the cap portion from the spout portion and simultaneously open the tip portion of the cylindrical portion, thereby forming a spout. The cap portion is shaped to cover the entire cylindrical portion, and the cap portion and the spout portion include a locking mechanism capable of locking the cap portion to the spout portion.
摘要:
An agent for thermally stabilizing lactoferrin, which comprises a nucleic acid as an active ingredient, can be added to lactoferrin to impart thermal stability to lactoferrin. Thermally stabilized lactoferrin can be heat-sterilized at a pH value around a neutral pH value while keeping its activity.
摘要:
A spout member 14 including a base portion 14a which is fixed to a bag body 11, a cylindrical portion 14b which protrudes upward from the base portion 14a, and a sealing portion 14c which seals a front end of the cylindrical portion 14b through a breakable thin portion 14d is disposed between two sheets of film forming the bag body 11. A sealing chamber 15 accommodating the cylindrical portion 14b and the sealing portion 14c is opened by tearing the two sheets of film along an opening assisting line 16. An opening assisting plate 14e protruding to at least one of a left side and a right side of the sealing portion 14c is disposed above the opening assisting line 16. A sandwiching reinforcement seal portion 17 for reinforcing the two sheets of film by sealing inner surfaces thereof is provided between the opening assisting plate 14e and the opening assisting line 16. According to the present invention, it is possible to provide a package bag in which a spout member is sealed between films forming a package bag and a series of operations of opening a bag and opening a spout can be promptly performed.