公开(公告)号：EP2457991A1

公开(公告)日：2012-05-30

申请号：EP10802340.9

申请日：2010-07-23

申请人： NIPRO CORPORATION ,  Reprocell Incorporated

发明人： MORIMOTO, Shinji ,  HAGIWARA, Yui

IPC分类号： C12M1/34 ,  G01N27/28 ,  G01N27/416

CPC分类号： B01L3/5085 ,  B01L2300/0645 ,  B01L2300/0829 ,  G01N33/4836

摘要： An object of the present invention is to provide a cellular electric potential measuring container with which an accurate measurement result can be readily obtained by bringing a cell into contact with a fine measurement electrode in cellular electric potential measurement using a cellular electric potential measuring container. The present invention provides a cellular electric potential measuring container comprising a container body and an electrode substrate, the electrode substrate being attached to a lower end of the container body so as to form a plurality of wells, the cellular electric potential measuring container being for measuring cellular electric potential after being mounted on an electric potential measuring device and, wherein the container body is made from resin and comprises a plurality of tubular portions whose upper and lower ends are open, each of the tubular portions comprises in an inner cavity a measurement portion tapered toward the lower end and having a measurement hole at the lower end, and further on an inner wall at least two retaining means retaining the measurement portion, the electrode substrate comprises a substrate body, with a plurality of measurement electrodes and a plurality of reference electrodes being disposed on one surface of the substrate body, and the container body is attached to the surface of the substrate body on which the measurement electrodes and the reference electrodes are disposed, such that the measurement electrodes are respectively exposed through the measurement holes.

摘要翻译： 本发明的目的是提供一种蜂窝电位测量容器，通过使用细胞电位测量容器在细胞电位测量中使细胞与细测量电极接触，可以容易地获得准确的测量结果。 本发明提供一种蜂窝电位测量容器，其包括容器主体和电极基板，所述电极基板安装在容器主体的下端以形成多个孔，所述蜂窝电位测量容器用于测量 蜂窝电位被安装在电位测量装置上，并且其中容器主体由树脂制成并且包括多个上端和下端开放的管状部分，每个管状部分在内腔中包括测量部分 在下端呈锥形并在下端具有测量孔，并且在内壁上还有至少两个保持测量部分的保持装置，电极基板包括具有多个测量电极和多个参考的基板主体 电极设置在基板主体的一个表面上，以及容器 主体附接到其上设置有测量电极和参考电极的基板主体的表面，使得测量电极分别通过测量孔露出。

公开(公告)号：EP2508875A1

公开(公告)日：2012-10-10

申请号：EP10834509.1

申请日：2010-11-22

申请人： Nipro Corporation

发明人： MORIMOTO, Shinji ,  HAGIWARA, Yui

IPC分类号： G01N27/28 ,  C12M1/34 ,  G01N27/30 ,  G01N27/416

CPC分类号： C12M41/46 ,  C12M23/12

摘要： An object of the present invention is to provide a cellular electric potential measuring container with which an accurate measurement result can be obtained without weakening or killing the cells to be measured in cellular electric potential measurement using a cellular electric potential measuring container. The present invention provides a container for measuring cellular electric potential after being mounted on an electric potential measuring device, comprising a container and an electrode substrate, the electrode substrate being attached to a lower end of the container so as to form a plurality of wells, wherein the container comprises a plurality of cylindrical portions whose upper and lower ends are open, the electrode substrate comprises a substrate and a plurality of measurement electrodes and a plurality of reference electrodes disposed on one surface of the substrate, the measurement electrodes and the reference electrodes at least comprise metal-plated copper wiring, a pair of a measurement electrode and a reference electrode are disposed on a bottom of each well, and the measurement electrodes and the reference electrodes are formed by a pre-plating method.

公开(公告)号：EP2077115B1

公开(公告)日：2016-12-14

申请号：EP07830193.4

申请日：2007-10-19

申请人： NIPRO CORPORATION

发明人： MORIMOTO, Shinji ,  SASAYAMA, Norihisa ,  SHIRASU, Akio

IPC分类号： A61K35/14 ,  A61B5/15 ,  A61M1/02 ,  G01N1/28 ,  G01N33/48

CPC分类号： A61M1/029 ,  A61B5/1416 ,  A61B5/15003 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150335 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/1535 ,  A61K35/16 ,  A61M5/31511 ,  A61M2005/3104 ,  A61M2005/3106 ,  A61M2005/31598 ,  A61M2202/0427

公开(公告)号：EP2077115A1

公开(公告)日：2009-07-08

申请号：EP07830193.4

申请日：2007-10-19

申请人： Nipro Corporation

发明人： MORIMOTO, Shinji ,  SASAYAMA, Norihisa ,  SHIRASU, Akio

IPC分类号： A61K35/14 ,  A61B5/15 ,  A61M1/02 ,  G01N1/28 ,  G01N33/48

CPC分类号： A61M1/029 ,  A61B5/1416 ,  A61B5/15003 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150335 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/1535 ,  A61K35/16 ,  A61M5/31511 ,  A61M2005/3104 ,  A61M2005/3106 ,  A61M2005/31598 ,  A61M2202/0427

摘要： This invention provides a platelet-rich plasma separator, which can carry out the separation of a platelet-rich plasma with a small number of gamma radiation sterilized instruments, and a platelet-rich plasma separation method. The platelet-rich plasma separator comprises a first syringe (10) and a second syringe (11). The first syringe (10) comprises a first syringe cylinder (13) provided with a first port (12) on which a blood collection needle can be mounted, a first cap (14) detachable from the first port (12), a first gasket (15) for sealing the first syringe cylinder (13) fluid-tightly, which first gasket (15) is reciprocated within the first syringe cylinder (13), and a first plunger (16) provided detachably on the first gasket (15). The second syringe (11) comprises a first hollow needle (30), which can be passed through the first gasket (15), a second syringe cylinder (32) having a second port (31) on which the first hollow needle (30) can be mounted, a second cap (33) detachable from the second port (32), a second gasket (34) for sealing the second syringe cylinder (32) liquid-tightly, which second gasket (34) is reciprocated within the second syringe cylinder (32), and a second plunger (35) provided detachably on the second gasket (34).

摘要翻译： 本发明提供了一种富含血小板的血浆分离器，其能够利用少量γ射线灭菌器具进行富含血小板的血浆的分离，以及富含血小板的血浆分离方法。 富含血小板的血浆分离器包括第一注射器（10）和第二注射器（11）。 第一注射器（10）包括设置有第一端口（12）的第一注射器筒（13），可以在其上安装采血针，从第一端口（12）可拆卸的第一帽（14），第一垫圈 （15），用于密封所述第一注射器筒（13），所述第一衬垫（15）在所述第一注射器筒（13）内往复运动，以及可拆卸地设置在所述第一衬垫（15）上的第一柱塞（16）。 第二注射器（11）包括可以穿过第一衬垫（15）的第一中空针（30），具有第二口（31）的第二注射器筒（32），第一中空针（30） 可以安装第二帽（33），其可与第二端口（32）分离;第二垫圈（34），用于液密地密封第二注射器筒（32），该第二垫圈（34）在第二注射器 气缸（32）和可拆卸地设置在第二垫圈（34）上的第二柱塞（35）。

公开(公告)号：EP2458373A1

公开(公告)日：2012-05-30

申请号：EP10802341.7

申请日：2010-07-23

申请人： NIPRO CORPORATION

发明人： MORIMOTO, Shinji ,  HAGIWARA, Yui

IPC分类号： G01N27/30 ,  C12M1/34 ,  G01N27/28 ,  G01N27/416

CPC分类号： G01N33/48728

摘要： An object of the present invention is to provide a cellular electric potential measuring container with which no wavy baseline occurs and an accurate measurement result can be readily obtained in cellular electric potential measurement using a cellular electric potential measuring container. The present invention provides a cellular electric potential measuring container comprising a container body and an electrode substrate, the electrode substrate being attached to a lower end of the container body so as to form a plurality of wells, the cellular electric potential measuring container being for measuring cellular electric potential after being mounted on an electric potential measuring device, wherein the container body comprises: a plurality of tubular portions whose upper and lower ends are open, and a portion reserved for attachment at the lower end, the electrode substrate comprises a substrate body, with a plurality of measurement electrodes and a plurality of reference electrodes being disposed on one surface of the substrate body, and the container body is attached by a double-sided tape to the surface of the substrate body on which the measurement electrodes and the reference electrodes are disposed, at a place of the portion reserved for attachment, and a method for producing a cellular electric potential measuring container.

摘要翻译： 本发明的目的是提供一种细胞电位测量容器，其中没有波浪基线发生，并且在使用蜂窝电位测量容器的细胞电位测量中可以容易地获得准确的测量结果。 本发明提供一种蜂窝电位测量容器，其包括容器主体和电极基板，所述电极基板安装在容器主体的下端以形成多个孔，所述蜂窝电位测量容器用于测量 在电位测量装置上安装蜂窝电位，其中容器主体包括：多个管状部分，其上端和下端是开放的，并且保留用于在下端附着的部分，电极基片包括基体 ，多个测量电极和多个参考电极设置在基板主体的一个表面上，并且容器主体通过双面胶带附接到其上具有测量电极和参考的基板主体的表面 电极设置在保留用于附接的部分的位置，以及一种方法 用于生产细胞电位测量容器。