公开(公告)号：EP1048649A4

公开(公告)日：2001-03-21

申请号：EP98961615

申请日：1998-12-25

申请人： NISSIN FOOD PRODUCTS LTD

发明人： YAMADA TOSHIHIRO ,  NOBUHARA YOICHI ,  KOBAYASHI KAZUHIRO ,  HIRANO SATOSHI ,  SAKURAI TAKANOBU ,  MIKAMI HIROSHI ,  MIYAKE AYAKO

IPC分类号： A61P29/02 ,  C07D207/32 ,  C07D207/333 ,  C07D207/30 ,  A61K31/40 ,  C07D403/04 ,  C07D405/04

CPC分类号： C07D207/333

摘要： Compounds represented by general formula (I) or salts thereof and anti-inflammatory agents and antitumor agents containing these compounds as the active ingredient, wherein R1 represents hydrogen or lower alkyl; R2 represents lower alkyl or (CH¿2?)n1 COOH (wherein n1 is 1, 2 or 3); R?3¿ represents hydrogen, halogeno, carboxy, etc.; R4 represents phenyl optionally having a specific substituent, dicyclic heteroaryl, phenylethynyl or lower alkynyl; and R5 represents lower alkyl, amino, etc.