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公开(公告)号：EP3359966B1
公开(公告)日：2020-01-01
申请号：EP16778831.4
申请日：2016-10-10
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公开(公告)号：EP2684053A1
公开(公告)日：2014-01-15
申请号：EP12707587.7
申请日：2012-03-07
发明人： KARL, Johann , RIEDLINGER, Julia , WILD, Norbert
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N33/6884 , G01N2333/914 , G01N2333/916 , G01N2800/122 , G01N2800/60
摘要： The present invention relates to an in vitro method aiding in the assessment of chronic obstructive pulmonary disease (= COPD). It discloses the use of the protein FEN1 as a marker of COPD. Furthermore, it especially relates to a method for assessing COPD from a sample, derived from an individual by measuring the protein FEN1 in said sample in vitro.
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公开(公告)号：EP2297581B1
公开(公告)日：2013-04-03
申请号：EP09772167.4
申请日：2009-07-01
IPC分类号： G01N33/574
CPC分类号： G01N33/57423 , G01N2333/4742
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公开(公告)号：EP2130048B1
公开(公告)日：2012-04-18
申请号：EP08716640.1
申请日：2008-03-19
发明人： HAGMANN, Marie-Luise , KARL, Johann , KLOECKNER, Julia , ROESSLER, Markus , TACKE, Michael , THIEROLF, Michael
IPC分类号： G01N33/574 , G01N33/573
CPC分类号： G01N33/57423 , G01N33/57488 , G01N2333/988
摘要： The present invention relates to the assessment of lung cancer. It discloses the use of protein APEX in the assessment of lung cancer. It also relates to a method for assessing lung cancer in vitro using a liquid sample, derived from an individual by measuring APEX in said sample. Measurement of APEX can, e.g., be used in the early detection or in the follow-up of patients with lung cancer.
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公开(公告)号：EP2380024A1
公开(公告)日：2011-10-26
申请号：EP09798890.1
申请日：2009-12-18
IPC分类号： G01N33/574
CPC分类号： G01N33/57488 , G01N33/57423 , G01N33/57484 , G01N2333/475 , G01N2800/52
摘要： The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the arginine-rich metastasized in early tumors protein (= ARMET) as a universal marker of different cancer types. ARMET aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g. of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are e.g. breast, ovary, cervix, head and neck, endometrium, melanoma, bladder, kidney, pancreas, prostate, esophagus, stomach or bile duct cancer. Furthermore, it especially relates to a method for assessing cancer from a liquid sample, derived from an individual by measuring ARMET in said sample. Measurement of ARMET can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
摘要翻译： 披露了一种帮助评估癌症的方法。 更具体地公开了在早期肿瘤蛋白（= ARMET）中转移的精氨酸富集作为不同癌症类型的通用标记物的用途。 ARMET有助于评估肺或肺癌（LC）或结肠癌，例如非小细胞肺癌（NSCLC）或结肠直肠癌（CRC），但也可能是其他特定类型的癌症。 这些特定的癌症类型是例如乳腺，卵巢，子宫颈，头颈部，子宫内膜，黑素瘤，膀胱，肾，胰腺，前列腺，食道，胃或胆管癌。 进一步公开了一种通过测量样品中的ARMET从个体获得的来自液体样品的癌症的方法。 ARMET的测量可以例如用于癌症的早期检测或用于进行手术的患者的监视。
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公开(公告)号：EP2223116A2
公开(公告)日：2010-09-01
申请号：EP08860118.2
申请日：2008-12-08
IPC分类号： G01N33/574
CPC分类号： G01N33/57419
摘要： The present invention relates to a method for assessing colorectal cancer (CRC) in vitro comprising measuring in a sample the concentration and/or activity of a seprase polypeptide and/or fragments thereof and of either anti-p53 and/or osteopontin and/or Ferritin, of optionally one or more other marker of CRC, and using the combined measurement result in the assessment of CRC. Furthermore, it especially relates to a method for assessing CRC from a liquid sample, derived from an individual by measuring seprase and at least anti-p53, Ferritin and/or osteopontin in said sample. The method according to the present invention can, e.g., be used in the early detection of cancer by screening of asymptomatic individuals or in the surveillance of patients who undergo surgery.
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8.发明授权
公开(公告)号：EP1579220B1
公开(公告)日：2007-08-15
申请号：EP03813582.8
申请日：2003-12-19
发明人： BERNDT, Peter , HAGMANN, Marie-Luise , LANGEN, Hanno , PALME, Stefan , ROESSLER, Markus , ROLLINGER, Wolfgang , TACKE, Michael , ZOLG, Werner , KARL, Johann , KOTT, Theresa
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , C12Q1/48
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of the protein nicotinamide N-methyltransferase (NNMT) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
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公开(公告)号：EP1676136A1
公开(公告)日：2006-07-05
申请号：EP04790499.0
申请日：2004-10-15
发明人： PESTLIN, Gabriele , ANDRES, Herbert , BERNDT, Peter , HAGMANN, Marie-Luise , KARL, Johann , LANGEN, Hanno , ZOLG, Werner
IPC分类号： G01N33/574
CPC分类号： G01N33/57415
摘要： The present invention relates to the diagnosis of breast cancer. It discloses the use of ubiquitin-conjugating enzyme E2N (UBC13) in the diagnosis of breast cancer. It relates to a method for diagnosis of breast cancer from a liquid sample, derived from an individual by measuring UBC13 in said sample. Measurement of UBC13 can, e.g., be used in the early detection or diagnosis of breast cancer.
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公开(公告)号：EP1654541A1
公开(公告)日：2006-05-10
申请号：EP04763897.8
申请日：2004-08-06
发明人： TACKE, Michael , BERNDT, Peter , HAGMANN, Marie-Luise , KARL, Johann , LANGEN, Hanno , PALME, Stefan , ROESSLER, Markus , ROLLINGER, Wolfgang , ZOLG, Werner
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , G01N2333/95
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein proteasome subunit alpha 3 (PSA3) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PSA3 in said sample. Measurement of PSA3 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
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