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1.发明授权4-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL) INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS 有权4-（杂环基）烷基-N-（芳基磺酰基）吲哚类化合物及其作为5-HT 6配体的
公开(公告)号：EP2121602B1
公开(公告)日：2015-03-18
申请号：EP07827524.5
申请日：2007-07-26
发明人： RAMAKRISHNA, Nirogi, Venkata, Satya , KAMBHAMPATI, Rama, Sastri , DESHPANDE, Amol, Dinkar , JASTI, Venkateswarlu
IPC分类号： C07D209/30 , A61K31/404 , A61P25/00
CPC分类号： C07D209/30
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2.发明公开4-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL) INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS 有权4-（杂环基）烷基-N-（芳基磺酰基）吲哚类化合物及其作为5-HT 6配体的
公开(公告)号：EP2121602A1
公开(公告)日：2009-11-25
申请号：EP07827524.5
申请日：2007-07-26
发明人： RAMAKRISHNA, Nirogi, Venkata, Satya , KAMBHAMPATI, Rama, Sastri , DESHPANDE, Amol, Dinkar , JASTI, Venkateswarlu
IPC分类号： C07D209/30 , A61K31/404 , A61P25/00
CPC分类号： C07D209/30
摘要： The present invention relates to novel 4-(Heterocyclyl)alkyl-N- (arylsulfonyl)indole compounds of the formula (I), their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. These compounds are useful in the treatment of various disorders that are related to 5-HT6 receptor functions. Specifically, the compounds of this invention are also useful in the treatment of various CNS disorders, hematological disorders, eating disorders, diseases associated with pain, respiratory diseases, genito-urological disorders, cardiovascular diseases and cancer.
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