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公开(公告)号：EP1178819A2
公开(公告)日：2002-02-13
申请号：EP00920596.4
申请日：2000-03-28
申请人： Ansovini, Raffaele
发明人： Ansovini, Raffaele
CPC分类号： A61K38/44 , C12Y108/01007
摘要： The present invention concerns the use of glutathione-reductase (GSSG reductase) for the preparation of a medicament for the treatment of HIV-infected patients, seropositive or already affected by AIDS, both for prophylactic and therapeutic use.
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公开(公告)号：EP3266875A1
公开(公告)日：2018-01-10
申请号：EP16759041.3
申请日：2016-03-04
CPC分类号： C12P21/02 , C12N9/0051 , C12N9/93 , C12N15/09 , C12N15/81 , C12Y108/01007 , C12Y108/03002 , C12Y603/02002 , C12Y603/02003
摘要： The present invention aims to provide a yeast that is genetically modified so as to more highly produce glutathione, and a method of producing glutathione utilizing the yeast. The present invention provides a method of producing glutathione, including culturing a yeast whose thiol oxidase activity is increased as compared to the parent strain in a culture medium to produce glutathione, and recovering glutathione from the cultured broth obtained.
摘要翻译： 本发明的目的在于提供经过遗传修饰的酵母，以便更高度地生产谷胱甘肽，以及利用该酵母生产谷胱甘肽的方法。 本发明提供生产谷胱甘肽的方法，包括在培养基中培养与亲本菌株相比硫醇氧化酶活性增加的酵母以产生谷胱甘肽，并从所得培养液中回收谷胱甘肽。
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3.发明公开COMPOSITION COMPRISING GLUTATHIONE REDUCTASE AND OXIDIZED GLUTATHIONE, AND THERAPEUTIC USES THEREOF 审中-公开组成和谷胱甘肽氧化型谷胱甘肽及其治疗用途
公开(公告)号：EP2600883A1
公开(公告)日：2013-06-12
申请号：EP11754493.2
申请日：2011-07-29
发明人： ANSOVINI, Raffaele
IPC分类号： A61K38/06 , A61K38/44 , A61K31/427 , A61P31/12 , A61P39/06
CPC分类号： A61K38/44 , A61K38/063 , A61K45/06 , C12Y108/01007 , Y02A50/465 , Y02A50/467 , A61K2300/00
摘要： Compositions comprising Glutathione Reductase (GSSG-r) and Oxidized Glutathione (GSSG) or pharmaceutically acceptable salts thereof for pharmaceutical use as antiviral and antibacterial agents and for the protection against the toxicity of free radicals and in particular radicals produced by the radiolysis of cellular water are provided. Methods of making and using such compositions are also provided.
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4.发明公开
公开(公告)号：EP3356326A1
公开(公告)日：2018-08-08
申请号：EP16785251.6
申请日：2016-09-29
申请人： Arkema France
IPC分类号： C07C319/06 , C12P11/00 , C07C231/04
CPC分类号： C12P11/00 , C07C319/06 , C12Y108/01007 , C12Y112/01 , C07C321/04
摘要： The invention relates to a method for producing mercaptans from disulfides and hydrogen by enzyme catalysis, and in particular for producing methylmercaptan from dimethyl disulfide and hydrogen.
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公开(公告)号：EP1178819B1
公开(公告)日：2003-11-12
申请号：EP00920596.4
申请日：2000-03-28
申请人： Ansovini, Raffaele
发明人： Ansovini, Raffaele
CPC分类号： A61K38/44 , C12Y108/01007
摘要： The present invention concerns the use of glutathione-reductase (GSSG reductase) for the preparation of a medicament for the treatment of HIV-infected patients, seropositive or already affected by AIDS, both for prophylactic and therapeutic use.
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公开(公告)号：EP3266875A4
公开(公告)日：2018-07-25
申请号：EP16759041
申请日：2016-03-04
发明人： HARA KIYOTAKA , KONDO AKIHIKO , IWASAKI AKIRA , IWAMOTO YUICHI
CPC分类号： C12P21/02 , C12N9/0051 , C12N9/93 , C12N15/09 , C12N15/81 , C12Y108/01007 , C12Y108/03002 , C12Y603/02002 , C12Y603/02003
摘要： The present invention aims to provide a yeast that is genetically modified so as to more highly produce glutathione, and a method of producing glutathione utilizing the yeast. The present invention provides a method of producing glutathione, including culturing a yeast whose thiol oxidase activity is increased as compared to the parent strain in a culture medium to produce glutathione, and recovering glutathione from the cultured broth obtained.
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公开(公告)号：EP1377313A1
公开(公告)日：2004-01-07
申请号：EP02732579.4
申请日：2002-04-08
CPC分类号： A61K38/44 , C12Y108/01007 , C12Y111/01009 , A61K2300/00
摘要： The use of GSSG-reductase in combination with glutathione peroxidase for the preparation of a medicament adjuvating the therapy with interferons.
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