利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

6 条记录 (耗时 0.009 秒)

    Use of n-piperidine derivative compositions for protecting biological systems
    1.
    发明公开
    Use of n-piperidine derivative compositions for protecting biological systems 有权
    Verwendung von N-Piperidinderivathaltigen Zusammensetzungen zum Schutz biologischer Systeme

    公开(公告)号：EP1815741A1

    公开(公告)日：2007-08-08

    申请号：EP06100589.8

    申请日：2006-01-19

    申请人： Medestea Research & Production S.R.L.

    发明人： Merizzi, Gianfranco ,  Soleti, Antonio

    IPC分类号： A01N1/02

    CPC分类号： A01N1/0226 ,  A01N1/02

    摘要： The present invention relates to compositions and the use of such compositions in the formulation of preservation solutions for protecting mammalian (including human) biological systems such as biotechnological preparations (including recombinant proteins), organs, tissues (including whole blood and blood derivatives such platelets and plasma) and cells (including red blood cells, pancreatic β-cells, stem cells and germ cells) from oxidative damage occurring, for example, during the different phases of transplantation and surgery. More particularly, this invention relates to a method for protecting and/or enhancing viability of mammalian biotechnological preparations/cells/tissues/organs during isolation (or harvesting), preservation (or storage), expansion (or colture), transplantation and surgery by using compositions containing effective amount of antioxidant cyclic (bis)-hydroxylamines derived from N-piperidine.

    摘要翻译： 本发明涉及组合物和这些组合物在制备用于保护哺乳动物（包括人）生物系统如生物技术制剂（包括重组蛋白），器官，组织（包括全血和血液衍生物如血小板和 血浆）和细胞（包括红细胞，胰腺2细胞，干细胞和生殖细胞）从氧化损伤发生，例如在移植和手术的不同阶段期间发生。 更具体地说，本发明涉及一种用于在分离（或收获），保存（或储存），扩张（或串联），移植和手术期间保护和/或增强哺乳动物生物技术制剂/细胞/组织/器官的活力的方法，其通过使用 含有有效量的衍生自N-哌啶的抗氧化环氧（双） - 羟胺的组合物。

    LONG CHAIN UNSATURATED OXYGENATED COMPOUNDS AND THEIR USE IN THE THERAPEUTICAL, COSMETIC AND NUTRACEUTICAL FIELD
    6.
    发明公开
    LONG CHAIN UNSATURATED OXYGENATED COMPOUNDS AND THEIR USE IN THE THERAPEUTICAL, COSMETIC AND NUTRACEUTICAL FIELD 有权
    长链不饱和化合物含有氧气和它们在治疗，美容和饮食区

    公开(公告)号：EP1515714A1

    公开(公告)日：2005-03-23

    申请号：EP03732804.4

    申请日：2003-06-16

    申请人： Medestea Research & Production S.R.L.

    发明人： CRAVOTTO, Giancario

    IPC分类号： A61K31/20

    CPC分类号： C07C57/03 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  C07C33/02 ,  C07C51/09 ,  C07C67/343 ,  C07C69/24 ,  C07C69/533 ,  C07C69/587

    摘要： Long-chain unsaturated oxygenated compounds and their use in the therapeutical, cosmetic and nutraceutical field. Use of compounds of formula R-X wherein X is a primary alcoholic functional group -CH20H, a carboxylic functional group -COON or a C1-C4 alkyl ester group, and of mono-, di- and tri-glycerides of acid compounds R-COON and of pharmaceutically acceptable salts of those acids, wherein R is a hydrocarbon chain having from 19 to 35 carbon atoms, which is saturated or unsaturated, including from one to five ethylenic or acetylenic unsaturations, linear or branched, including from one to five methyl branches, and optionally substituted by from one to three hydroxyl groups, for the preparation of pharmaceutical or nutraceutical compositions useful for the treatment and prevention of pathologies related to a high concentration of cholesterol and lipids, pathologies associated with an increased ability of the blood platelets to aggregate and with a reduced concentration of oxygen, in the treatment of ageing processes, for the preparation of compositions of nutritional integrators aimed at weight loss and cosmetic compositions useful in the treatment and prevention of skin damage caused by free radicals.