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公开(公告)号:EP2471942B1
公开(公告)日:2014-12-24
申请号:EP10811606.2
申请日:2010-07-01
申请人: Ajinomoto Co., Inc.
发明人: DOI, Hidetaka , USUDA, Yoshihiro
CPC分类号: C12P13/08 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/78 , C12N9/80 , C12P13/12 , C12P13/227 , C12Y203/01109 , C12Y206/01081 , C12Y305/01096 , C12Y305/03023
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公开(公告)号:EP2471942A4
公开(公告)日:2013-05-15
申请号:EP10811606
申请日:2010-07-01
申请人: AJINOMOTO KK
发明人: DOI HIDETAKA , USUDA YOSHIHIRO
CPC分类号: C12P13/08 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/78 , C12N9/80 , C12P13/12 , C12P13/227 , C12Y203/01109 , C12Y206/01081 , C12Y305/01096 , C12Y305/03023
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公开(公告)号:EP2471942A1
公开(公告)日:2012-07-04
申请号:EP10811606.2
申请日:2010-07-01
申请人: Ajinomoto Co., Inc.
发明人: DOI, Hidetaka , USUDA, Yoshihiro
CPC分类号: C12P13/08 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/78 , C12N9/80 , C12P13/12 , C12P13/227 , C12Y203/01109 , C12Y206/01081 , C12Y305/01096 , C12Y305/03023
摘要: A method for producing an L-amino acid which comprisese culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid producing ability in a medium to produce and accumulate an L-amino acid in the medium and collecting the L-amino acid from the medium, wherein the bacterium has been modified so that activity or activities of one or two or more kinds of enzymes of the arginine succinyltransferase pathway, such as arginine succinyltransferase, succinylarginine dihydrolase, succinylornithine aminotransferase, succinylglutamate-semialdehyde dehydrogenase and succinylglutamate desuccinylase, is/are decreased.
摘要翻译: 一种生产L-氨基酸的方法,包括在培养基中培养属于肠杆菌科并具有L-氨基酸生产能力的细菌以在培养基中生产和积累L-氨基酸并收集L-氨基酸 其中所述细菌已经被修饰以便精氨酸琥珀酰转移酶途径的一种或两种或更多种酶如精氨酸琥珀酰转移酶,琥珀酰精氨酸二氢酶,琥珀酰鸟氨酸转氨酶,琥珀酰谷氨酸半醛脱氢酶和琥珀酰谷氨酸脱琥珀酰化酶的活性或活性是 /减少。
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