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公开(公告)号：EP1042344B1
公开(公告)日：2003-11-12
申请号：EP98960961.5
申请日：1998-12-16
CPC分类号： G11C13/0019 , B82Y10/00 , C07H21/00 , C12Q1/6818 , C12Q1/686 , G11C13/0014 , H01L51/0077 , H01L51/0093 , H01L51/0595 , Y10S977/885 , C12Q2563/173 , C12Q2563/137 , C12Q2531/113 , C12Q2565/101
摘要： The invention provides conductive polymers comprising metal-containing nucleic acid duplexes electrically coupled to an electron source. Methods for making conductive metal-containing nucleic acid duplexes are provided, comprising subjecting a nucleic acid duplex to basic conditions in the presence of a divalent metal cation. Methods of using conductive metal-containing nucleic acid duplexes are provided, including methods of genomic analysis, methods of molecular screening and immunological methods that produce antibodies to such molecules.
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2.发明授权A molecular memory obtained using DNA strand molecular switches and carbon nanotubes, and manufacturing method thereof 有权分子存储器与DNA链作为分子开关和碳纳米管，以及相关的制造方法
公开(公告)号：EP1376606B1
公开(公告)日：2008-12-03
申请号：EP02425408.8
申请日：2002-06-20
CPC分类号： G11C13/025 , B82Y10/00 , G06N3/123 , G11C13/0014 , G11C13/0019 , G11C2213/77 , G11C2213/81 , H01L27/28 , H01L51/0048 , H01L51/0093 , H01L51/0595 , Y10S977/855 , Y10S977/885
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3.发明公开
公开(公告)号：EP1292361A1
公开(公告)日：2003-03-19
申请号：EP01939491.5
申请日：2001-05-25
发明人： MIRKIN, Chad, A. , PINER, Richard , HONG, Seunghun
CPC分类号： B82B3/00 , B05D1/007 , B05D1/185 , B05D1/26 , G01Q80/00 , G03F7/0002 , G03F7/165 , Y10S977/849 , Y10S977/853 , Y10S977/854 , Y10S977/855 , Y10S977/856 , Y10S977/857 , Y10S977/86 , Y10S977/88 , Y10S977/884 , Y10S977/885 , Y10S977/886 , Y10S977/895 , Y10T428/24802
摘要： The invention provides a lithographic method referred to as 'dip pen' nanolithography (DPN). DPN utilizes a scanning probe microscope (SPM) tip (e.g., an atomic force microscope (AFM) tip) as a 'pen', a solid-state substrate (e.g., gold) as 'paper', and molecules with a chemical affinity for the solid-state substrate as 'ink'. Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecules in submicrometer dimensions, making DPN useful in the fabrication of a variety of microscale and nanoscale devices. The invention also provides substrates patterned by DPN, including submicrometer combinatorial arrays, and kits, devices and software for performing DPN. The invention further provides a method of performing AFM imaging in air. The method comprises coating an AFM tip with a hydrophobic compound, the hydrophobic compound being selected so that AFM imaging performed using the coated AFM tip is improved compared to AFM imaging performed using an uncoated AFM tip. Finally, the invention provides AFM tips coated with the hydrophobic compounds.
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4.发明公开
公开(公告)号：EP1292361A4
公开(公告)日：2004-07-07
申请号：EP01939491
申请日：2001-05-25
申请人： UNIV NORTHWESTERN
发明人： MIRKIN CHAD A , PINER RICHARD , HONG SEUNGHUN
IPC分类号： B05D1/00 , B05D1/18 , B05D1/26 , B82B3/00 , G01Q10/00 , G01Q60/00 , G01Q70/06 , G01Q70/16 , G01Q80/00 , G03F7/00 , G03F7/16 , G03F7/20 , H01L21/027 , A61N5/00 , G03F1/00 , G21G5/00
CPC分类号： B82B3/00 , B05D1/007 , B05D1/185 , B05D1/26 , G01Q80/00 , G03F7/0002 , G03F7/165 , Y10S977/849 , Y10S977/853 , Y10S977/854 , Y10S977/855 , Y10S977/856 , Y10S977/857 , Y10S977/86 , Y10S977/88 , Y10S977/884 , Y10S977/885 , Y10S977/886 , Y10S977/895 , Y10T428/24802
摘要： The invention provides a lithographic method referred to as 'dip pen' nanolithography (DPN). DPN utilizes a scanning probe microscope (SPM) tip (e.g., an atomic force microscope (AFM) tip) as a 'pen', a solid-state substrate (e.g., gold) as 'paper', and molecules with a chemical affinity for the solid-state substrate as 'ink'. Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecules in submicrometer dimensions, making DPN useful in the fabrication of a variety of microscale and nanoscale devices. The invention also provides substrates patterned by DPN, including submicrometer combinatorial arrays, and kits, devices and software for performing DPN. The invention further provides a method of performing AFM imaging in air. The method comprises coating an AFM tip with a hydrophobic compound, the hydrophobic compound being selected so that AFM imaging performed using the coated AFM tip is improved compared to AFM imaging performed using an uncoated AFM tip. Finally, the invention provides AFM tips coated with the hydrophobic compounds.
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公开(公告)号：EP1042344A1
公开(公告)日：2000-10-11
申请号：EP98960961.5
申请日：1998-12-16
CPC分类号： G11C13/0019 , B82Y10/00 , C07H21/00 , C12Q1/6818 , C12Q1/686 , G11C13/0014 , H01L51/0077 , H01L51/0093 , H01L51/0595 , Y10S977/885 , C12Q2563/173 , C12Q2563/137 , C12Q2531/113 , C12Q2565/101
摘要： The invention provides conductive polymers comprising metal-containing nucleic acid duplexes electrically coupled to an electron source. Methods for making conductive metal-containing nucleic acid duplexes are provided, comprising subjecting a nucleic acid duplex to basic conditions in the presence of a divalent metal cation. Methods of using conductive metal-containing nucleic acid duplexes are provided, including methods of genomic analysis, methods of molecular screening and immunological methods that produce antibodies to such molecules.
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6.发明授权
公开(公告)号：EP1292361B1
公开(公告)日：2008-02-20
申请号：EP01939491.5
申请日：2001-05-25
发明人： MIRKIN, Chad, A. , PINER, Richard , HONG, Seunghun
CPC分类号： B82B3/00 , B05D1/007 , B05D1/185 , B05D1/26 , G01Q80/00 , G03F7/0002 , G03F7/165 , Y10S977/849 , Y10S977/853 , Y10S977/854 , Y10S977/855 , Y10S977/856 , Y10S977/857 , Y10S977/86 , Y10S977/88 , Y10S977/884 , Y10S977/885 , Y10S977/886 , Y10S977/895 , Y10T428/24802
摘要： The invention provides a lithographic method referred to as 'dip pen' nanolithography (DPN). DPN utilizes a scanning probe microscope (SPM) tip (e.g., an atomic force microscope (AFM) tip) as a 'pen', a solid-state substrate (e.g., gold) as 'paper', and molecules with a chemical affinity for the solid-state substrate as 'ink'. Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecules in submicrometer dimensions, making DPN useful in the fabrication of a variety of microscale and nanoscale devices. The invention also provides substrates patterned by DPN, including submicrometer combinatorial arrays, and kits, devices and software for performing DPN. The invention further provides a method of performing AFM imaging in air. The method comprises coating an AFM tip with a hydrophobic compound, the hydrophobic compound being selected so that AFM imaging performed using the coated AFM tip is improved compared to AFM imaging performed using an uncoated AFM tip. Finally, the invention provides AFM tips coated with the hydrophobic compounds.
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公开(公告)号：EP1080229A4
公开(公告)日：2005-07-13
申请号：EP99924378
申请日：1999-05-20
IPC分类号： C12N15/09 , C12M1/00 , C12M1/34 , C12N1/12 , C12N11/00 , C12N15/10 , C12P19/34 , C12Q1/68 , G11C13/02 , H01L21/336 , H01L29/06 , H01L29/78 , H01L29/861 , H01L51/00 , H01L51/05 , H01L51/30 , H01L51/40
CPC分类号： H01L51/0595 , B82Y10/00 , C12N15/10 , C12Q1/68 , G11C13/0014 , G11C13/0019 , H01L51/0002 , H01L51/0093 , Y10S977/885 , Y10S977/925 , Y10S977/941
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8.发明公开A molecular memory obtained using DNA strand molecular switches and carbon nanotubes, and manufacturing method thereof 有权分子存储器与DNA链作为分子开关和碳纳米管，以及相关的制造方法
公开(公告)号：EP1376606A1
公开(公告)日：2004-01-02
申请号：EP02425408.8
申请日：2002-06-20
CPC分类号： G11C13/025 , B82Y10/00 , G06N3/123 , G11C13/0014 , G11C13/0019 , G11C2213/77 , G11C2213/81 , H01L27/28 , H01L51/0048 , H01L51/0093 , H01L51/0595 , Y10S977/855 , Y10S977/885
摘要： Described herein are a molecular memory obtained using DNA strand molecular switches and carbon nanotubes, and a manufacturing method thereof. In particular, the nonvolatile memory is manufactured according to an architecture that envisages the use of carbon nanotubes as electrical connectors and DNA strands as physical means on which to write the information. In other words, the nonvolatile memory is made by means of a set of molecular DNA strand switches, the addressing of which is controlled by molecular wires made up of carbon nanotubes.
摘要翻译： 在描述的是使用DNA获得海滩分子开关和碳纳米管的分子存储器，以及它们的制造方法。 特别地，非易失性存储器是在架构制造雅丁到并设想使用碳纳米管作为电连接器和DNA链作为物理装置在其上写入信息。 换句话说，所述非易失性存储器是由一组分子DNA海滩开关的手段制成的所有其通过由碳纳米管的分子线控制的寻址。
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公开(公告)号：EP1080229A1
公开(公告)日：2001-03-07
申请号：EP99924378.5
申请日：1999-05-20
IPC分类号： C12Q1/68
CPC分类号： H01L51/0595 , B82Y10/00 , C12N15/10 , C12Q1/68 , G11C13/0014 , G11C13/0019 , H01L51/0002 , H01L51/0093 , Y10S977/885 , Y10S977/925 , Y10S977/941
摘要： The present invention provides nano-scale devices, including electronic circuits, using DNA molecules as a support structure. DNA binding proteins are used to mask regions of the DNA as a material, such as a metal is coated onto the DNA. Included in the invention are DNA based transistors, capacitors, inductors and diodes. The present invention also provides methods of making integrated circuits using DNA molecules as a support structure. Methods are also included for making DNA based transistors, capacitors, inductors and diodes.
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