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    A preparation used for anti-tachyarrhythmia and its preparation method
    5.
    发明公开
    A preparation used for anti-tachyarrhythmia and its preparation method 审中-公开
    Zubereitung zur Verwendung bei anti-Tachyarrhythmie sowie Methode zu dessen Zubereitung

    公开(公告)号：EP2679233A1

    公开(公告)日：2014-01-01

    申请号：EP13173515.1

    申请日：2013-06-25

    申请人： Heshengyuan of Chinese Medicine Research & Development Company Limited in Shunde District of Foshan

    发明人： Chen, Keji ,  Du, Shouying ,  Ma, Xiaochang

    IPC分类号： A61K36/505 ,  A61P9/06

    摘要： A kind of Corydalis extract for anti-tachyarrhythmia, the extract prepared by the following method:Corydalis crude powder 100 parts by weight, is extracted by 60-80% ethanol 600-1000 parts by volume in 1-3 times, combined filtrate, concentrated under reduced pressure to a fluidextract of the relative density of 0.2 - 0.5g/mL; take the processed D101 resin, and the fluidextract prepared through the resin column with the flow rate of 0.2 - 0.5mL/min, impurity of deionized water with the flow rate of 0.2 - 0.5mL/min, 60-90% ethanol elution, flow rate 0.4 - 0.8mL/min, and recover ethanol, concentrate to Corydalis extract dry paste. According to the conventional method of adding conventional accessories, made into clinically acceptable pills, capsules, granules, tablets, oral liquid or injection. The extract has obvious effect on anti-arrhythmia.

    摘要翻译： 一种延胡索提取物用于抗快速性心律失常，通过以下方法制备的提取物：延胡索粗粉末100重量份，用60-80％乙醇600-1000体积份提取1-3次，合并滤液，浓缩 在减压下加入0.2-0.5g / mL的相对密度的流质提取物; 取经处理的D101树脂，通过树脂柱制备的流质量为0.2 - 0.5mL / min，去离子水杂质为0.2 - 0.5mL / min，60-90％乙醇洗脱流动 速率为0.4 - 0.8mL / min，回收乙醇，浓缩至延胡索提取物干浆。 根据常规添加常规方法，制成临床上可接受的药丸，胶囊，颗粒剂，片剂，口服液或注射液。 提取物对抗心律失常有明显作用。