公开(公告)号：EP3601289B1

公开(公告)日：2024-10-16

申请号：EP18715595.7

申请日：2018-03-28

发明人： MOSER, Rudolf ,  GROEHN, Viola ,  BLATTER, Fritz ,  SZELAGIEWICZ, Martin ,  BOEHNI STAMM, Ruth ,  RUETTIMANN, Markus ,  LAPADULA, Giuseppe

IPC分类号： C07D475/04 ,  A61K31/519 ,  C07C215/08 ,  C07D295/088 ,  A61P25/24 ,  A61P7/06

公开(公告)号：EP4408436A1

公开(公告)日：2024-08-07

申请号：EP22877521.9

申请日：2022-09-28

申请人： The Trustees of The University of Pennsylvania

发明人： MITCHELL, Michael ,  BILLINGSLEY, Margaret M.

IPC分类号： A61K31/7088 ,  A61K9/107 ,  A61K9/127 ,  A61K9/51 ,  A61K47/54 ,  A61P31/04 ,  A61P35/00 ,  C07C215/08

CPC分类号： A61K9/1271 ,  A61K9/0019 ,  A61K47/543 ,  A61K47/6929 ,  A61K47/6835 ,  A61K45/06

公开(公告)号：EP4317141A1

公开(公告)日：2024-02-07

申请号：EP22382756.9

申请日：2022-08-04

申请人： Curia Spain S.A.U.

发明人： ENCINAS MADRAZO, Soledad ,  RODRÍGUEZ FERRER, Patricia

IPC分类号： C07D265/30 ,  C07C215/08 ,  C07C215/10

摘要： The present invention relates to an efficient and industrially applicable process for the preparation of 2-substituted morpholine derivatives such as viloxazine and to intermediates useful therefor.

公开(公告)号：EP3766969B1

公开(公告)日：2023-10-04

申请号：EP20193685.3

申请日：2015-04-10

发明人： KANEKO, Kotaro ,  KANEKO, Nobuhiro ,  KAWAI, Koji

IPC分类号： C12N9/96 ,  C07C215/08 ,  C07C215/10 ,  C07C215/12 ,  C07C215/40 ,  C07C229/12

公开(公告)号：EP3983372B1

公开(公告)日：2023-08-09

申请号：EP20729077.6

申请日：2020-06-02

发明人： ERNST, Martin ,  HUBER, Tatjana ,  MELDER, Johann-Peter ,  JAEGLI, Stephanie ,  KRUG, Thomas

IPC分类号： C07C209/26 ,  C07C213/02 ,  C07C215/08 ,  C07C211/10

公开(公告)号：EP4180417A1

公开(公告)日：2023-05-17

申请号：EP21837909.7

申请日：2021-06-25

申请人： ADEKA CORPORATION

发明人： SAKURAI, Atsushi ,  HATASE, Masako ,  OKADA, Nana ,  FUKUSHIMA, Ryota

IPC分类号： C07C215/08 ,  C07F1/08 ,  C07F15/04 ,  C07F15/06 ,  C07F7/22 ,  C23C16/18 ,  C23C16/40

摘要： The present invention provides an alkoxide compound represented by the following general formula (1), a thin-film forming raw material containing the compound, and a method of producing a thin-film:

where R 1 and R 2 each independently represent a hydrogen atom, an alkyl group having 1 to 5 carbon atoms, or a fluorine atom-containing alkyl group having 1 to 5 carbon atoms, R 3 and R 4 each independently represent an alkyl group having 1 to 5 carbon atoms, or a fluorine atom-containing alkyl group having 1 to 5 carbon atoms, R 5 represents a hydrogen atom, a fluorine atom-containing group, or an alkyl group having 1 to 5 carbon atoms, R 6 represents a fluorine atom-containing group, M represents a metal atom or a semimetal atom, and "n" represents the valence of the atom represented by M, provided that when M represents a copper atom, R 3 and R 4 each independently represent an alkyl group having 1 or 2 carbon atoms, and R 5 represents a hydrogen atom.

公开(公告)号：EP3611160B1

公开(公告)日：2023-03-29

申请号：EP18789939.8

申请日：2018-04-27

发明人： ZHANG, Bo ,  DING, Xiaohua ,  DAI, Dongcheng ,  LEI, Sijun ,  LIU, Xueming ,  DUAN, Panpan ,  CHEN, Yongkai ,  WANG, Chaodong

IPC分类号： C07C233/47 ,  C07C211/05 ,  C07C215/08 ,  C07D295/027 ,  A61K31/216 ,  A61K31/41 ,  A61P9/12 ,  A61P9/04

公开(公告)号：EP3737663A1

公开(公告)日：2020-11-18

申请号：EP19704380.5

申请日：2019-01-08

申请人： University Court of The University of St Andrews

发明人： WIDEGREN, Magnus ,  CLARKE, Matthew Lee

IPC分类号： C07C213/00 ,  C07D209/20 ,  C07C215/24 ,  C07C215/28 ,  C07C215/08 ,  C07C29/149 ,  C07C33/34

公开(公告)号：EP3601289A1

公开(公告)日：2020-02-05

申请号：EP18715595.7

申请日：2018-03-28

申请人： Merck Patent GmbH

发明人： MOSER, Rudolf ,  GROEHN, Viola ,  BLATTER, Fritz ,  SZELAGIEWICZ, Martin ,  BOEHNI STAMM, Ruth ,  RUETTIMANN, Markus ,  LAPADULA, Giuseppe

IPC分类号： C07D475/04 ,  A61K31/519 ,  C07C215/08 ,  C07D295/088 ,  A61P25/24 ,  A61P7/06

公开(公告)号：EP3466916A1

公开(公告)日：2019-04-10

申请号：EP17805638.8

申请日：2017-05-11

申请人： Shandong University Of Technology

发明人： BI, Gehua ,  BI, Yusui

IPC分类号： C07C51/41 ,  C07C53/06 ,  C07C41/03 ,  C07C43/11 ,  C07C213/04 ,  C07C269/00 ,  C07C271/02 ,  C07C213/08 ,  C07C215/08 ,  C08G65/28 ,  C08J9/08

摘要： An organic amine salt compounds of general formula A n- [B m+ ] p (I) is disclosed, wherein A n- is a CO 2 -donating anion with a valence of -n, wherein n = 1, 2 or 3; each B m+ comprises: ammonium ion, hydrazinium ion and/or organic amine B cation; wherein m = 1-10; 0 p ≤ n m ; and wherein A n- is one or more selected from a group consisting of following anions: (a) carbamate orcarbazate; (b) carbonate; (c) formate; (d) bicarbonate; (e) organic monocarbonate; (f) organic poly-carbamate; (g) orthoformate; or (h) organic poly-carbonate. The compound of general formula (I) has at least one of hydroxyalkyl group linked to N atom, i.e., has alkanolamine residue. They can be used as polyurethane foaming agent, and most of them can be used as polystyrene foaming agent or polyvinyl choride foaming agent.