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    INFORMATION PROCESSING DEVICE, METHOD FOR OPERATING INFORMATION PROCESSING DEVICE, OPERATION PROGRAM FOR INFORMATION PROCESSING DEVICE, METHOD FOR GENERATING CALIBRATED STATE PREDICTION MODEL, AND CALIBRATED STATE PREDICTION MODEL
    9.
    发明公开
    INFORMATION PROCESSING DEVICE, METHOD FOR OPERATING INFORMATION PROCESSING DEVICE, OPERATION PROGRAM FOR INFORMATION PROCESSING DEVICE, METHOD FOR GENERATING CALIBRATED STATE PREDICTION MODEL, AND CALIBRATED STATE PREDICTION MODEL 审中-公开

    公开(公告)号：EP4439053A1

    公开(公告)日：2024-10-02

    申请号：EP22895301.4

    申请日：2022-10-14

    申请人： FUJIFILM Corporation

    发明人： SUGITA, Yui

    IPC分类号： G01N21/65 ,  C12M1/34 ,  C12M3/00 ,  G01N33/483 ,  G06N3/02 ,  G06N20/00

    CPC分类号： C12M1/34 ,  C12M3/00 ,  G01N21/65 ,  G01N33/483 ,  G06N3/02 ,  G06N20/00 ,  G01N2201/129620130101

    摘要： An information processing apparatus is an information processing apparatus that predicts a state of a component in a suspension in which biological molecules are dispersed as the components in a liquid, based on spectrum measurement data obtained by measuring a spectrum of electromagnetic waves emitted from the suspension, the information processing apparatus including: a processor, in which the processor uses a calibrated state predictive model calibrated by using at least two types of calibration data of first calibration data and second calibration data, the first calibration data including first spectrum measurement data, which is the spectrum measurement data obtained from a first suspension containing a first component, and first component relation information related to the first component as explanatory variables, and including first state relation information related to a state of the first component as a response variable, and the second calibration data including second spectrum measurement data, which is the spectrum measurement data obtained from a second suspension containing a second component, and second component relation information related to the second component as explanatory variables, and including second state relation information related to a state of the second component as a response variable, acquires target component relation information related to a target component, which is a target of which the state is predicted, and target spectrum measurement data, which is the spectrum measurement data obtained from a target suspension containing the target component, and applies the target component relation information and the target spectrum measurement data to the calibrated state predictive model, and causes the calibrated state predictive model to output a target state prediction result obtained by predicting the state of the target component in the target suspension.

    METHOD FOR PERFORMING BIOPROCESSES ON LIQUID IMMUNE OR NAIVE CELL CULTURES
    10.
    发明公开
    METHOD FOR PERFORMING BIOPROCESSES ON LIQUID IMMUNE OR NAIVE CELL CULTURES 审中-公开

    公开(公告)号：EP4435085A1

    公开(公告)日：2024-09-25

    申请号：EP23164135.8

    申请日：2023-03-24

    申请人： The Automation Partnership (Cambridge) Ltd.

    发明人： Stacey, Adrian ,  Prouté, Fanny

    IPC分类号： C12M1/36 ,  C12M3/00 ,  G01N35/00

    CPC分类号： C12M41/48 ,  C12M23/44 ,  C12M23/42

    摘要： The invention relates to a method for performing bioprocesses on liquid immune or naive cell cultures, wherein an integrated bioprocessing system (1) performs multiple unit operations (3) of a first bioprocess on a cell culture to obtain a processed cell culture, wherein the processed cell culture is destined for autologous or allogenic cell therapy, wherein a control module (7) of the integrated bioprocessing system (1) performs the unit operations (3) according to a first protocol describing a workflow (8) with order and configuration of the unit operations (3), wherein a measurement module of the integrated bioprocessing system (1) measures parameters of the performance of the unit operations (3), wherein the first protocol includes at least one branching of the workflow (8) into at least two branches, each of the branches including at least one unit operation (3), wherein, depending on the measured parameters, the control module (7) follows one of the branches. It is proposed, that the measurement module sends the measured parameters to a storage module, that the storage module stores the measured parameters in relation to the first protocol, that the stored parameters are communicated to a deciding entity for a decision about a step in a further bioprocess, that the control module (7) receives the decision from the deciding entity, and, that the control module (7) performs the further bioprocess based on the decision.