公开(公告)号：EP0744164B1

公开(公告)日：2003-09-10

申请号：EP96303613.2

申请日：1996-05-21

申请人： Cook Incorporated

发明人： Kavteladze, Zaza A. ,  Korshok, Aleksandr P., Potechina Ul. 15, Kv 30 ,  Kadnikov, Andrej A. ,  Hansen, Palle ,  Kirts, Beth Ann

IPC分类号： A61F2/06

CPC分类号： A61F2/90 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9665 ,  A61F2210/0019

公开(公告)号：EP1330194A1

公开(公告)日：2003-07-30

申请号：EP01992533.8

申请日：2001-11-01

申请人： Cook Incorporated

发明人： GREENBERG, Roy, K. ,  IVANCEV, Krasnodar ,  PAUL, Ram, H. Jr.

IPC分类号： A61B17/22

CPC分类号： A61B17/221 ,  A61B2017/00867 ,  A61B2017/22035 ,  A61B2017/22038 ,  A61B2017/2215 ,  A61B2090/08021 ,  A61F2/95

摘要： A medical grasping device (10) for vascular use, having an outer sheath (12), an elongate control member (50) extending an outer sheath (12) to a distal tip section (54), and a proximal control assembly (22) including an actuation section (24) joined to the elongate control member (50). Adjacent to the distal tip section (54) is a grasping portion (70, 70') that is extendable from the outer sheath (12) to create loops (74,74') for grasping a target object (T) for repositioning within the vascular system, or for removal from the patient, with loops being retractable into the outeer sheath to hold the target object against the device (10) during movement of the device. Elongate control member (50) is preferably a cannula or tube having a lumen (58) extending completely therethrough for placement over a guide wire (28) already in the patient.

公开(公告)号：EP1251805A2

公开(公告)日：2002-10-30

申请号：EP01910431.4

申请日：2001-02-05

申请人： Cook Incorporated ,  Cook Biotech, Inc.

发明人： PAVCNIK, Dusan ,  KELLER, Frederick, S. ,  ROSCH, Josef ,  OSBORNE, Thomas, A. ,  BATES, Brian, L. ,  DEFORD, John, A. ,  DIXON, Christopher, G. ,  HOFFA, Andrew, K. ,  LEONARD, Raymond, B., II ,  OBERMILLER, Joseph, F. ,  OSBORNE, Thomas, A.

IPC分类号： A61F2/24 ,  A61B17/12 ,  A61F2/06

CPC分类号： A61B17/12022 ,  A61B17/12172 ,  A61F2/01 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2002/018 ,  A61F2230/0008 ,  A61F2230/001 ,  A61F2230/0023 ,  A61F2230/0026 ,  A61F2230/005 ,  A61F2230/0058 ,  A61F2230/0095

摘要： A multiple-sided medical device (10) comprises a frame (11) comprising wire or other resilient material and having a series of bends (12) and interconnecting sides. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs (16) for anchoring purposes. A full or partial covering (45) of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device (51), a stent graft (75), or an implantable, intraluminal valve (43) such as for correcting incompetent veins in the lower legs and feet.

公开(公告)号：EP0906129B1

公开(公告)日：2002-08-28

申请号：EP97928775.2

申请日：1997-06-04

申请人： Cook Incorporated

发明人： FISCHER, Frank, J., Jr.

IPC分类号： A61L29/00 ,  A61M25/00 ,  A61L31/00 ,  A61L33/00

CPC分类号： A61M25/0045 ,  A61F2250/0035 ,  A61F2250/0067 ,  A61K51/1282 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/406 ,  A61L2300/42 ,  A61L2300/45 ,  A61M31/002 ,  C08L83/04

摘要： An implantable medical device (10) such as a catheter with a pharmacologically active ingredient layered between outer and inner elongated member tubes (11 and 13) for minimizing the risk of infection or other physiological afflictions associated with the implantation thereof. The outer and inner elongated member tubes include a base material mixed with a bioactive material including, for example, one and/or the other of rifampin and minocycline. An itermediate tube or layer (18) is positioned between and in communication with the outer and inner elongated member tubes (11 and 13). The intermediate tube or layer also includes a base material of, for example, silicone with a pharmacologically active ingredient mixed therein. The slower diffusion rate minocycline is included as or part of the bioactive material in the base material of the outer and inner elongated member tubes. The pharmacologically active ingredient or bioactive material such as a mixture of rifampin and minocycline is included in the base material of the intermediate tube or layer, which permeates through the inner and outer member tubes and diffuses therefrom or therethrough for treating tissues surrounding the catheter concomitantly.

公开(公告)号：EP1140268A2

公开(公告)日：2001-10-10

申请号：EP99961964.6

申请日：1999-12-16

申请人： Cook Incorporated

发明人： PARKER, Fred, T.

IPC分类号： A61M25/00

CPC分类号： A61M25/0068 ,  A61M25/005 ,  A61M25/0069 ,  A61M25/008 ,  A61M25/0662 ,  A61M2025/0081

摘要： Disclosed is a catheter, more particularly a guiding catheter (10). The guiding catheter (10) comprises an inner layer (46), a reinforcement layer (24), and an outer layer (16). The reinforcement layer (46) generally extends from the proximal end (14) of the guiding catheter (10) and terminates proximal to the distal end (18) of the guiding catheter. The distal portion of the guiding catheter (10) comprises a soft material to facilitate manipulation. The reinforcement layer (24) can be attached to the inner layer (46) and the outer layer (16) attaches to both the reinforcement layer (24) and the inner layer (46). Proximal portion of the guiding catheter can have a folded cuff (52).

公开(公告)号：EP1120128A1

公开(公告)日：2001-08-01

申请号：EP00610014.3

申请日：2000-01-28

申请人： William Cook Europe ApS ,  Cook Incorporated

发明人： Klint, Henrik Sonderskov

IPC分类号： A61M25/00

CPC分类号： A61M25/0043 ,  A61M25/005 ,  A61M25/0053 ,  A61M2025/09191

摘要： A catheter system comprises a catheter having a distal end (2), a body portion (3) and at least one lumen (6) extending through the body portion in the longitudinal direction from a proximal end (4) towards the distal end. There is at least one central member for co-axial advancement through the catheter lumen.

摘要翻译： 导管系统包括具有远端（2），主体部分（3）和至少一个内腔（6）的导管，所述至少一个内腔（6）从近端（4）朝向远端在纵向方向上延伸穿过主体部分。 存在至少一个用于通过导管内腔同轴前进的中心构件。

公开(公告)号：EP1113764A1

公开(公告)日：2001-07-11

申请号：EP00948716.6

申请日：2000-07-17

申请人： MED INSTITUTE, INC. ,  Cook Incorporated

发明人： FEARNOT, Neal, E. ,  WANINGER, Matthew, S. ,  CHOULES, Brian ,  DEBRUYNE, Michael, P.

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/848 ,  A61F2/95 ,  A61F2002/075 ,  A61F2002/9511 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067

摘要： An expandable stent prosthesis is disclosed in which the apices of the bends located at at least one end of the stent are individually twisted at an angle to the circumference of the stent to form a fan blade-like arrangement when viewed from that end. The fan blade-like arrangement allows the stent to expand from the compressed condition during deployment such that likelihood of a strut or bend of the stent become entangled with a barb or adjacent strut or bend, is reduced. In one embodiment of the invention, the fan blade-like arrangement results from plastically deforming the individual apices, while in another embodiment, the apices are twisted into the fan blade-like arrangement during the loading process, such as by use of a suture thread to pull the apices into alignment.

公开(公告)号：EP1011813A1

公开(公告)日：2000-06-28

申请号：EP98948171.8

申请日：1998-09-11

申请人： Cook Incorporated ,  MED INSTITUTE, INC. ,  Apple, Marc G.

发明人： APPLE, Marc, G. ,  BATES, Brian, L. ,  DEFORD, John, A. ,  FEARNOT, Neal, E.

IPC分类号： A61N5/10 ,  A61N5/00

CPC分类号： A61M25/1011 ,  A61M2025/1047 ,  A61M2025/1072 ,  A61N5/1002 ,  A61N5/1048

摘要： A catheter apparatus (20) and radiation dosimetry unit indicator (21) for delivery of a prescribed radiation dose to a patient. The catheter is filled with a radiation carrier material such as an inert radioactive gas (12) for the treatment of, for example, restenosis after angioplasty, and malignancies. The inflated catheter includes a plurality of discrete chambers such as balloon sections (22, 24, 26) for transporting the radioactive carrier material, and a plurality of discrete chambers (32, 34, 36) enabling substantial blood flow through the artery during treatment with the prescribed radiation. The inflated catheter can also comprise a one unit balloon. A specific metal coating enhances the radiation dose delivered to the target. The wall (25) of the inflation lumen attenuates transmission dose to the blood circulating through the hollow inner lumen of the catheter device. The system also creates increased by-product radiation, from the impact of beta particles and gamma protons travelling toward the lumen wall. A radiation dosimetry unit indicator (21) is positioned, disposed, or affixed to a calibrated catheter to assist the physician in prescribing radiation activity and exposure times.

公开(公告)号：EP0925077A2

公开(公告)日：1999-06-30

申请号：EP97954888.0

申请日：1997-08-22

申请人： Cook Biotech, Inc. ,  MED INSTITUTE, INC. ,  Cook Incorporated

发明人： COOK, William A. ,  HILES, Michael C. ,  KOZMA, Thomas G. ,  PATEL, Umesh H.

IPC分类号： C12N5 ,  A61F2 ,  A61K35 ,  A61L2 ,  A61L27 ,  A61L29 ,  A61L31

CPC分类号： A61L27/24 ,  A61F2/06 ,  A61F2/07 ,  A61L2/0088 ,  A61L27/3604 ,  A61L27/3662 ,  A61L27/3683 ,  A61L27/3695 ,  A61L27/3839 ,  A61L27/3843 ,  A61L27/386 ,  A61L29/005 ,  A61L31/005 ,  Y10S623/925

摘要： A graft prosthesis (11), materials and method for implanting, transplanting, replacing, or repairing a part of a patient. The graft prosthesis includes a purified, collagen-based matrix structure removed from a submucosa tissue source. The submucosa tissue source is purified by disinfection and removal steps to deactivate and remove contaminants, thereby making the purified structure biocompatible and suitable for grafting on and/or in a patient.

公开(公告)号：EP0553344B1

公开(公告)日：1998-09-23

申请号：EP92919117.9

申请日：1992-08-18

申请人： Cook Incorporated

发明人： Eberbach, Mark Allen

IPC分类号： A61F2/00 ,  A61B17/00

CPC分类号： A61F2/0063 ,  A61B17/00234 ,  A61F2002/0068 ,  A61F2002/0072 ,  A61F2210/0014 ,  A61F2250/0098

摘要： A method and apparatus for use by a surgeon to repair a weakened, deranged portion of the anatomy of a patient comprising a sheath (48) having a distal end positionable within a patient and a proximal end positioned exterior thereof for manipulation by a surgeon, the sheath being of a length to extend from exterior of a patient through a laparoscopic opening into a surgical cavity of the patient; a prothesis (14) movable from interior of the sheath to a location adjacent to the deranged portion to be repaired, the prothesis having an elongated passageway located adjacent to the periphery thereof; and an introducer (32) positioned within the sheath and having a distal end coupled to the prothesis, the introducer adapted to effect the movement of the prothesis from interior of the sheath to exterior thereof and to expand the prothesis to a functionally expanded orientation adjacent to the part to be repaired.

摘要翻译： 一种由外科医生使用以修复患者的解剖结构的弱化部分的方法和装置，所述方法和装置包括护套（48），所述护套具有可定位在患者体内的远端和定位在其外部的用于外科医生操纵的近端， 护套的长度从患者的外部通过腹腔镜开口延伸到患者的手术腔中; 可从护套内部移动到邻近要修复的错位部分的位置的假体（14），假体具有位于其周边附近的细长通道; 以及定位在护套内并具有联接到假体上的远端的导引器（32），导引器适于实现假体从护套内部到护套外部的运动，并且将假体扩张到功能扩张取向， 要修复的部分。