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91.发明公开CONFORMATIONAL-SPECIFIC ANTIBODIES AGAINST OLIGOMERS 有权KONFORMATIONSSPEZIFISCHE抗生素GEGEN淀粉样蛋白（BETA）-OLIGOMERE
公开(公告)号：EP2847217A1
公开(公告)日：2015-03-18
申请号：EP13724769.8
申请日：2013-05-08
发明人： BAYER, Thomas
IPC分类号： C07K16/18
CPC分类号： C07K16/18 , C07K2317/33 , C07K2317/34 , C07K2317/565 , C07K2317/76 , G01N33/6896 , G01N2500/02 , G01N2500/10 , G01N2800/2821
摘要： The present disclosure relates to a conformational specific antibody molecule recognizing a conformational epitope of human trimeric or tetrameric Αβ oligomers, wherein said antibody molecule does not bind human monomeric Αβ 1-42 or human Ap 1-42 dimers; and pharmaceutical and diagnostic compositions comprising said antibody molecule as well as methods using same.
摘要翻译： 本公开涉及识别人三聚体或四聚Aβ寡聚体的构象表位的构象特异性抗体分子，其中所述抗体分子不与人单体Aβ1-42或人Ap 1-42二聚体结合; 以及包含所述抗体分子的药物和诊断组合物以及使用其的方法。
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公开(公告)号：EP2661287B1
公开(公告)日：2015-01-14
申请号：EP11801604.7
申请日：2011-12-15
发明人： FRIEDRICH, Martin
IPC分类号： A61M1/00
CPC分类号： A61M1/0031 , A61M1/0025 , A61M1/0033 , A61M1/0035 , A61M2205/3344 , A61M2205/3375 , F04B2205/12
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93.发明公开Method and neuroprosthetic device for monitoring and suppression of pathological tremors through neurostimulation of the afferent pathways 审中-公开由传入的神经通路的刺激神经假体的方法和装置用于监测和病理震颤的抑制
公开(公告)号：EP2801389A1
公开(公告)日：2014-11-12
申请号：EP13382169.4
申请日：2013-05-08
申请人： CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) , Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin
IPC分类号： A61N1/36
CPC分类号： A61N1/36139 , A61N1/36014 , A61N1/36025 , A61N1/36067 , A61N1/37235
摘要： Method and neuroprosthetic device for monitoring and suppression of pathological tremors in a user through the neurostimulation of the afferent pathways to the brain, which comprises wearable elements placed over the parts of the body affected by tremor, wherein said wearable elements (1) have bioelectric sensors (3) generating a first signal characterization of tremor, biomechanical sensors (4) generating a second signal characterization of tremor, a programmable electronic device (9) comprised of a control, acquisition and processing module of the first and second characterization signals, and a signal generator for the afferent stimulation based on the first and second signal characterization and stimulation electrodes (8) which transmit the neuromodulation signals to the afferent pathways projecting into the central nervous system to modulate the activity of the neural structures responsible for tremor generation.
摘要翻译： 方法和用于在通过所述传入神经通路到大脑的方法，包括放置在受震颤所述主体的所述部分可佩戴元件的神经刺激用户监测和病理震颤抑制神经假体设备，worin所述可佩戴元件（1）具有生物传感器 （3）产生的震颤的第一信号特性，生物力学传感器（4）产生的震颤的第二信号特性，可编程的电子设备（9）包括在第一和第二特征信号的控制，获取和处理模块，以及一 基于所述第一和第二信号表征和刺激电极用于传入刺激信号发生器（8），该传送神经调制信号到传入神经通路突出到中枢神经系统以调节负责震颤代神经结构的活性。
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公开(公告)号：EP2315651B1
公开(公告)日：2014-02-26
申请号：EP09744046.5
申请日：2009-08-19
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95.发明授权Popcorn enhaltende Span- und/oder Faserplatte, sowie Herstellungsverfahren 有权爆米花enhaltende颗粒和/或纤维板，以及制造方法
公开(公告)号：EP2081743B1
公开(公告)日：2013-12-11
申请号：EP07820865.9
申请日：2007-10-02
IPC分类号： B27N3/00
CPC分类号： B27N3/00 , Y10T428/253 , Y10T428/268 , Y10T428/31971 , Y10T428/31982 , Y10T428/31986 , Y10T428/31989
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公开(公告)号：EP2536543A1
公开(公告)日：2012-12-26
申请号：EP11709890.5
申请日：2011-02-16
摘要： The invention relates to molded bodies which contain lignocellulose, which are free of binding agents, and which achieve certain parameters with respect to density, heat conductivity, and strength. The invention further relates to enzymatic wet methods and enzymatic dry methods for producing insulating materials, wherein an incubating solution is used as presented in the description.
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公开(公告)号：EP1931393B1
公开(公告)日：2012-08-22
申请号：EP06792191.6
申请日：2006-09-20
CPC分类号： A61L2/18 , A61F13/36 , A61F15/001 , A61F2013/8414 , A61L2/0088 , A61L2/26 , A61L2202/16
摘要： The present invention relates to a disinfection system, arrangements comprising at least two sequentially arranged disinfection systems and containers comprising various chambers usable for the disinfection system. In particular, the present inventions relates to a disinfection system comprising at least one chamber adapted for containing at least one first chamber adapted to contain disinfectant and at least one second chamber adapted to contain at least one swab and/or sponge, said at least one swab and/or sponge and additional separated space for taking up the disinfectant. The system is designed such that a predetermined amount of disinfectant is brought into contact with the at least one swab and/or one sponge immediately before use.
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98.发明公开Behandlung von multipler Sklerose und/oder rheumatoider Arthritis 审中-公开Behandlung von multipler Sklerose und / oder rheumatoider Arthritis
公开(公告)号：EP2481757A1
公开(公告)日：2012-08-01
申请号：EP12165439.6
申请日：2007-04-02
申请人： Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin , Klinikum der Universität Regensburg - Anstalt des Öffentlichen Rechts-
CPC分类号： C07K16/2866 , A61K2039/505
摘要： Die Erfindung betrifft die Verwendung eines Antikörpers, der an Loop 1 und Loop 2 des Chemokinrezeptors CCR2 spezifisch binden kann, zur Herstellung eines Medikamentes zur Behandlung von multipler Sklerose und/oder rheumatoider Arthritis bei einem Subjekt. Vorzugsweise ist das Subjekt ein Primat oder Mensch. In einer anderen Ausführungsform betrifft die vorliegende Erfindung die Verwendung eines Antikörpers, der an Loop 1 und Loop 2 des Chemokinrezeptors CCR2 spezifisch binden kann, in einem Verfahren zum Depletieren von Monozyten.
摘要翻译： 特异性结合趋化因子受体（CCR）2的抗体用于生产用于治疗受试者中的多发性硬化症和/或类风湿性关节炎的药物的用途，或用于制备用于制备用于 要求保护受试者中多发性硬化或类风湿性关节炎的治疗。 包括用于单核细胞消耗的独立权利要求，包括使单核细胞与抗体接触，并排除代表人或动物体外科手术或治疗性治疗的程序。 活动：神经保护; 抗关节炎; 抗风湿。 作用机理：CCR2粘合剂。
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公开(公告)号：EP2081743A2
公开(公告)日：2009-07-29
申请号：EP07820865.9
申请日：2007-10-02
IPC分类号： B27N3/00
CPC分类号： B27N3/00 , Y10T428/253 , Y10T428/268 , Y10T428/31971 , Y10T428/31982 , Y10T428/31986 , Y10T428/31989
摘要： The present invention relates to the use of popcorn as a structure-enhancing and dimensionally stabilizing material for molded bodies comprising lignocellulose, such as wood and/or composite materials, and a method for production of a molded body comprising lignocellulose.
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