摘要:
The present invention relates to a method for alkylating a molecule or an ion, wherein the molecule or the ion is alkylated by reacting it with an alkylating agent, wherein the alkylating agent is a compound according to formula (1). In the formula (1), R 1 is a substituted or unsubstituted C 1-20 hydrocarbon residue or a polymer, R 2 is a substituted or unsubstituted C 1-20 hydrocarbon residue or a hydrogen atom, R 3 is absent, a substituted or unsubstituted C 1-20 hydrocarbon residue or a hydrogen atom, R 4 and R 5 are linked with each other to form an aromatic group or are independently from each other selected from the group consisting of a hydrogen atom, substituted and unsubstituted C 1-20 hydrocarbon residues and electron withdrawing groups, X 1 is an oxygen atom, a nitrogen atom or a sulfur atom, wherin R 3 is not present in formula (1) if X 1 is an oxygen atom or a sulfur atom, Z is a covalent bond or an aromatic group and A - is an anion.
摘要:
Provided herein are Nα,Nα,Nα-trialkyl histidine derivative compounds and methods of their preparation. Also provided are methods of their use for preparing useful compounds such as ergothioneine.
摘要:
The present invention relates to N-substituted aminobenzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives of the formula (I),(II), (III) or (IV) or a physiologically tolerated salt thereof. The invention relates topharmaceutical compositions comprising such N-substituted amino-benzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives, and the use of such N-substituted aminobenzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives for therapeutic purposes. The N-substituted aminobenzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives are GlyT1 inhibitors.