公开(公告)号：EP0622088B1

公开(公告)日：1998-04-29

申请号：EP94201205.5

申请日：1990-01-18

申请人： Cook Incorporated

发明人： Gianturco, Cesare ,  Osborne, Thomas A.

IPC分类号： A61M29/00

CPC分类号： A61F2/86 ,  A61F2/89 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9528 ,  A61F2220/0058

公开(公告)号：EP0804936A2

公开(公告)日：1997-11-05

申请号：EP97302755.0

申请日：1997-04-22

申请人： Cook Incorporated

发明人： Ely, Joseph F. ,  Rothbarth, Leo ,  Miller, Frank J. ,  John, David St.

IPC分类号： A61M25/00

CPC分类号： A61M25/007

摘要： A method for predetermining the controlled and uniform discharge rate of a fluid from a single lumen tubular body having passageways radially extending through the wall of the tubular body has been developed and is described. The method involves predetermining such parameters as the transverse cross-sectional areas of the passageways extending through the wall of the tubular body, the spacing of the passageways, the pressure at each of the passageways, and the rate of flow at each of the passageways. One specific preferred application of such a tubular body is an infusion catheter for delivering various fluids to designated areas of the body for either a therapeutic treatment and/or diagnostic purposes. For example, such a catheter may be adapted to deliver controlled and uniform quantities of thrombolytic agents, chemotherapeutic agents as well as such diagnostic agents as fluorescent dies and radioactive agents.

摘要翻译： 已经开发了一种用于预测来自具有径向延伸穿过管状体的壁的通道的单管腔管体的流体的受控均匀排出速率的方法。 该方法包括预先确定诸如延伸穿过管状体的壁的通道的横截面积，通道的间隔，每个通道处的压力以及每个通道处的流速的参数。 这种管状体的一个特别优选的应用是用于将各种流体输送到身体的指定区域用于治疗性治疗和/或诊断目的的输注导管。 例如，这样的导管可以适于递送可控和均匀量的溶栓剂，化学治疗剂以及诸如荧光管和放射性试剂的诊断剂。

公开(公告)号：EP0784989A2

公开(公告)日：1997-07-23

申请号：EP97300178.7

申请日：1997-01-14

申请人： Cook Incorporated

发明人： Ciaglia, Pasquale ,  Fischer, Frank J. Jr.

IPC分类号： A61M16/04

CPC分类号： A61M16/0488 ,  A61M16/0431 ,  A61M16/0434 ,  A61M16/0445 ,  A61M16/0472

摘要： A method and device (10) for providing an ostomy (102) through the wall (100) of the trachea. The method employs a balloon catheter (16) including an inflatable balloon (18), and entails percutaneously inserting the tip (56) of a wire guide (54) through the tracheal wall (100) so that the wire guide (54) lies across the tracheal wall (100); positioning the catheter (16) over the wire guide (54); advancing the catheter (16) along the wire guide (54) until the balloon (18) lies across the tracheal wall (100); and inflating the balloon (18) to atraumatically dilate a portion of the tracheal wall (100), thereby forming an ostomy (102). The method desirably includes the further steps of deflating the balloon (18) and inserting a tracheal tube (20) into the ostomy (102). The tracheal tube (20) can be positioned in the open ostomy (102) after removing the balloon (18) from the ostomy (102). However, the method is preferably carried out employing a device (10) having a dilator tube (12) which carries the catheter (16) and tracheal tube (20) on it. Such a construction allows the dilator tube (12), the balloon catheter (16) and the tracheal tube (20) to be advanced on the wire guide (54) together. The tracheal tube (20) can include an inflatable circumferential cuff (24) on it, providing a seal between the tracheal tube (20) and the tracheal wall (100). The diameter of the balloon (18) preferably is at least equal to, and more preferably is slightly greater than, the maximum diameter of any portion of the tracheal tube (20) (such as the uninflated cuff (24)) to be inserted into the ostomy (102). The method and device (10) of the present invention are particularly advantageous in that the ostomy (102) can be formed atraumatically and enlarged without risk of perforating the rear of the trachea, and in that the close dilation or slight overdilation of the ostomy (102), along with the taper of the distal end (14) of the dilator tube (12), protect the cuff (24) from damage during insertion of the tracheal tube (20) through the ostomy (102).

摘要翻译： 一种用于通过气管的壁（100）提供造口术（102）的方法和装置（10）。 该方法采用包括可充气球囊（18）的球囊导管（16），并且需要经皮插入导线器（54）的尖端（56）穿过气管壁（100），使得导线器（54）位于 气管壁（100）; 将导管（16）定位在导线器（54）上方; 沿导丝器（54）推进导管（16）直到球囊（18）穿过气管壁（100）; 并使气囊（18）膨胀以使气管壁（100）的一部分无损伤地膨胀，从而形成造口术（102）。 该方法理想地包括进一步的步骤，使气囊（18）放气并将气管管（20）插入造口术（102）。 在将气囊（18）从造口术（102）中取出后，气管管（20）可定位在开放式造口术（102）中。 然而，该方法优选使用具有在其上承载导管（16）和气管管（20）的扩张管（12）的装置（10）进行。 这种结构允许扩张管（12），球囊导管（16）和气管管（20）一起在导线器（54）上前进。 气管管（20）可以包括在其上的可充气圆周箍（24），在气管管（20）和气管壁（100）之间提供密封。 气囊（18）的直径优选地至少等于并且更优选略微大于要插入的气管管（20）（例如未膨胀的袖带（24））的任何部分的最大直径 造口术（102）。 本发明的方法和装置（10）是特别有利的，因为造口术（102）可以无损伤地形成和扩大，而没有穿过气管后部的风险，并且造口术的紧密扩张或轻微过度扩张 102）与扩张管（12）的远端（14）的锥度一起，在气管插管（20）通过造口术（102）插入期间保护袖带（24）免受损伤。

公开(公告)号：EP0748186A1

公开(公告)日：1996-12-18

申请号：EP95913994.0

申请日：1995-03-08

申请人： Cook Incorporated

发明人： HALL, Todd, A. ,  PARKER, Fred, T.

IPC分类号： A61B17 ,  A61F2

CPC分类号： A61B17/1215 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12172 ,  A61B17/12177 ,  A61B2017/2215 ,  A61M25/09 ,  A61M2025/09175

摘要： A percutaneous release mechanism (57) for use with an intravascular treatment device (11) in an intravascular treatment system (10). The release mechanism includes an inner member (17) having a connection mechanism (18) positioned about the distal end (14) thereof for interconnection with another connection mechanism (12) positioned on an intravascular treatment device. The release mechanism also includes an outer member tube (13) of which the inner member is positioned therein. The first and second connection mechanisms are interconnectable and positionable in the passage (16) of the tube for delivering the treatment device in a delivery state to the treatment site. The release mechanism also includes a handle (37) having parts (38, 39) connected to the inner member and outer tube, whereby movement of the proximal end of the inner member is translated to the distal end thereof for extending the interconnected connection mechanisms from the passage of the outer member tube and positioning the treatment device in a treatment state. The intravascular treatment system includes the percutaneous release mechanism along with the intravascular treatment device. The treatment device includes an occlusion coil (23) and a rigid tube (36) connected to the flexible outer member tube (35) for maintaining the delivery coil in a delivery state. In another example, the treatment device includes a blood clot filter (40) in which the percutaneous delivery mechanism is adapted for connection thereto.

公开(公告)号：EP0744164A1

公开(公告)日：1996-11-27

申请号：EP96303613.2

申请日：1996-05-21

申请人： Cook Incorporated

发明人： Kavteladze, Zaza A. ,  Korshok, Aleksandr P., Potechina Ul. 15, Kv 30 ,  Kadnikov, Andrej A. ,  Hansen, Palle ,  Kirts, Beth Ann

IPC分类号： A61F2/06

CPC分类号： A61F2/90 ,  A61F2/95 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9665 ,  A61F2210/0019

摘要： A prosthetic device for sustaining a vessel or hollow organ lumen (a stent) has a tubular wire frame (1) with rows of elongate cells (2) having a larger axis and a smaller axis. The cells are arranged with the larger axis in the circumferential direction of the frame (2) and the smaller axis parallel to the axial direction thereof. Each cell is formed by two U-shaped wire sections, and in a plane perpendicular to the longitudinal axis one of the branches of the U-shaped wire sections in one row form together a closed ring shape (4) which provides the frame (1) with large radial stiffness. In the axial direction the frame (1) has only low stiffness so that it easily conforms to the vascular wall even if this deforms due to external loads. The interconnection between the cells (2) may be flexible.

摘要翻译： 用于维持血管或中空器官腔（支架）的假体装置具有管状线框架（1），其具有具有较大轴线和较小轴线的细长细胞排（2）。 电池在框架（2）的圆周方向上具有较大的轴线，并且平行于其轴向方向的较小的轴线布置。 每个电池由两个U形电线部分形成，并且在垂直于纵轴的平面中，一行中的U形电线部分的一个分支形成一个闭合环形（4），该环形形状（4）提供框架 ）具有较大的径向刚度。 在轴向方向上，框架（1）仅具有低刚度，使得即使由于外部载荷而变形，也容易符合血管壁。 单元（2）之间的互连可以是柔性的。

公开(公告)号：EP0520692B1

公开(公告)日：1996-08-28

申请号：EP92305610.5

申请日：1992-06-18

申请人： Cook Incorporated

发明人： Parker, Fred T.

IPC分类号： A61M25/00

CPC分类号： A61M25/0069 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/0053 ,  A61M25/0108

公开(公告)号：EP0550258B1

公开(公告)日：1996-07-10

申请号：EP92311771.7

申请日：1992-12-23

申请人： Cook Incorporated

发明人： Hall, Todd

IPC分类号： A61M25/01

CPC分类号： A61M25/09 ,  A61M2025/09166 ,  A61M2025/09175

公开(公告)号：EP0662806A1

公开(公告)日：1995-07-19

申请号：EP94906451.0

申请日：1993-12-20

申请人： Cook Incorporated

发明人： BOATMAN, Scott, E. ,  BRUMMETT, Kimberly D., Route I

IPC分类号： A61F2

CPC分类号： A61F2/885 ,  A61F2/92 ,  A61F2/958 ,  A61F2240/001 ,  A61F2250/0098

摘要： A flexible stent (10) having a waveform pattern (13) formed from a sheet (11) of biocompatible material (39) and into a tubular shape (12) for maintaining the patency of a lumen such as in a coronary vessel. The waveform pattern of the stent is formed from a flat sheet of malleable, biocompatible material by, for example, photochemically etching the sheet and leaving a framework (44) or plurality of closed cells (17-19). The waveform pattern is formed into a tubular shape around a deflated, delivery catheter balloon (35) with segments (24, 25) of the closed cells being interposed only overlapping a reinforcing member (14) extending longitudinally along the stent. The stent material is treated to reduce the coefficient of friction of the material and to aid in the radial expansion of the stent with the balloon. Radiopaque markers (41, 42) are positioned at the ends (15, 16) of the stent to aid the physician in positioning the stent at an occlusion site.

公开(公告)号：EP0405823B1

公开(公告)日：1994-11-30

申请号：EP90306729.6

申请日：1990-06-20

申请人： Cook Incorporated

发明人： Bates, Brian L. ,  Osborne, Thomas A.

IPC分类号： A61M25/01

CPC分类号： A61M25/09 ,  A61M2025/09091 ,  A61M2025/09166

公开(公告)号：EP0624380A1

公开(公告)日：1994-11-17

申请号：EP94303223.5

申请日：1994-05-04

申请人： Cook Incorporated

发明人： Drewes Jr., David A. ,  Parker, Fred T.

IPC分类号： A61M25/01 ,  A61M25/00

CPC分类号： A61M25/0108 ,  A61M2025/0163

摘要： A flexible plastic material catheter having a distal tubular member portion with a greater than 75 weight percent loading of a radiopaque agent for radiographic viewing. The catheter comprises an elongated member having a proximal portion and a distal end portion with a flexible, radiopaque plastic material having a durometer lower than that of the proximal portion. The plastic material of the distal end portion comprises a homogeneous and evenly dispersed composition of a 20 weight percent base thermoplastic, elastomer material such as a polyether block amide and 80 weight percent loading of a radiopaque agent such as tungsten. This distal end portion plastic material exhibits a durometer of approximately 47 on the Shore D scale, whereas the polyether block amide material exhibits a durometer of approximately 40 on the Shore D scale. The flex modulus of the polyether block amide material is in range of 23,000 to 75,000 pounds per square inch. The proximal end portion comprises a base thermoplastic material such as a polyamide elastomer material and a radiopaque agent of bismuth oxychloride.

摘要翻译： 具有穿通通道的细长构件形式的导管具有第二柔性不透射线塑料材料的近端部分（11）和第一柔性不透射线塑料材料的远端部分（12），硬度计较低 比近端部分的材料。 远端部分的材料是均匀的，并且包含重量比75％的不透射线剂。 导管包括近端管（11），其包括由聚酯弹性体，聚氨酯，聚酰胺弹性体或聚醚嵌段酰胺组成的基底热塑性材料，和第二不透射线剂，其选自氯氧化铋，亚碳酸铋，三氧化铋，钡 硫酸盐或钨。