公开(公告)号：EP1836479A1

公开(公告)日：2007-09-26

申请号：EP04801250.4

申请日：2004-12-01

Applicant: CITY TECHNOLOGY LIMITED

Inventor： CUTLER, Stuart, Christopher ,  VASS, Alexander

IPC: G01N21/35

CPC classification number: G01N21/3504 ,  G01N21/314 ,  G01N21/71 ,  G01N2021/0385 ,  G01N2201/0236 ,  G01N2201/024 ,  G01N2201/0632

Abstract: A gas sensor comprises a cavity for containing a gas, means for generating radiation which is transmitted through the cavity and includes one or more wavelengths which is absorbed in use by a gas to be detected; and a detector for detecting radiation which has passed through the cavity. The walls of the cavity are sufficiently reflective to the radiation that the cavity is substantially uniformally illuminated with the radiation.

Abstract translation: 一种气体传感器，包括用于容纳气体的空腔，用于产生透过所述空腔的辐射的装置，所述辐射包括被待检测的气体吸收的一种或多种波长， 以及检测器，用于检测已经穿过腔体的辐射。 空腔的壁对辐射具有足够的反射性，使得空腔基本上与辐射一起被照射。

公开(公告)号：EP1761641A2

公开(公告)日：2007-03-14

申请号：EP05739547.7

申请日：2005-05-06

Applicant: Clondiag Chip Technologies GmbH

Inventor： DWORRAK, Alexandra ,  ELLINGER, Thomas ,  ERMANTRAUT, Eugen ,  SCHULZ, Torsten ,  ULLRICH, Thomas ,  KAISER, Thomas

IPC: C12Q1/68

CPC classification number: B01L3/502738 ,  B01L3/50851 ,  B01L7/52 ,  B01L7/525 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0864 ,  B01L2300/0877 ,  B01L2300/1827 ,  B01L2300/1838 ,  B01L2400/0481 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2201/024

Abstract: The invention relates to devices and methods for detecting specific interactions between probe and target molecules. The invention especially relates to a device for the qualitative and/or quantitative detection of molecular interactions between probe and target molecules, which comprises a) a microarray comprising a substrate on which probe molecules are immobilized on array elements, said microarray being located on a first surface of the device; and b) a reaction chamber that is defined between the first area with the microarray disposed thereon and a second surface, the distance between the microarray and the second surface being modifiable.

公开(公告)号：EP1754044A1

公开(公告)日：2007-02-21

申请号：EP05753805.0

申请日：2005-05-26

Applicant: Envision Instruments, LLC ,  Williams, Paul C.

Inventor： WILLIAMS, Paul C.

IPC: G01N21/53 ,  G01N21/85 ,  G01N21/27 ,  C12M1/34 ,  G01J1/32

CPC classification number: G01N21/534 ,  G01N21/274 ,  G01N21/4785 ,  G01N21/8507 ,  G01N2021/8535 ,  G01N2201/0218 ,  G01N2201/024 ,  G01N2201/1242 ,  G01N2201/12746

Abstract: An in-situ technique is provided for automatically verifying proper operation of a photometric device, such as a cell density probe (CDP). The CDP has a first detector and a second detector. The first detector senses light that is transmitted from a light source of the CDP. The second detector senses light that has passed through an optical gap at a tip of the CDP, wherein the sensed light has been reduced in intensity due to light absorption. Electrical current provided to the light source is reduced, and the resultant values of a light characteristic (such as intensity) are sensed. These values from the detectors are compared against one or more predicted values. If the CDP is operating properly, the values from the detectors will be consistent with the predicted values. If there is a malfunction in the CDP, then the values from the detectors will be inconsistent with the predicted values.

公开(公告)号：EP1297324B1

公开(公告)日：2006-06-21

申请号：EP01927330.9

申请日：2001-04-25

Applicant: Ondeo Nalco Company

Inventor： RASIMAS, Jeffrey, P. ,  FEHR, Michael, J. ,  HOOTS, John, E.

IPC: G01N33/18 ,  G01N21/64 ,  G02B6/24

CPC classification number: G01N21/645 ,  G01N2201/024 ,  Y10T436/25

Abstract: Described and claimed is a modular fluorometer and a method of using same to control an industrial water system, wherein said modular fluorometer comprises: one or more units with each unit comprising: a channel comprising an optically appropriate cell through which a water sample flows; a light source positioned outside said optically appropriate cell; an optional excitation filter positioned between the light source and the optically appropriate cell; a reference detector positioned outside the optically appropriate cell; an emission detector positioned outside the optically appropriate cell; an optional emission filter positioned between said emission detector and said optically appropriate cell; wherein if more than one unit is present in said modular fluorometer, said optically appropriate cells through which said water sample flows are aligned such that only one channel through which a water sample flows exists in said fluorometer.

公开(公告)号：EP1291625B1

公开(公告)日：2006-04-26

申请号：EP02396135.2

申请日：2002-09-06

Applicant: WALLAC OY

Inventor： Aronkytö, Petri ,  Harju, Raimo ,  Myllynpää, Asko

IPC: G01J3/02 ,  G01N21/64

CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0275 ,  G01N21/253 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/024

公开(公告)号：EP1121581B1

公开(公告)日：2006-02-15

申请号：EP99947384.6

申请日：1999-09-18

Applicant: Carl Zeiss

Inventor： VÖLCKER, Martin ,  FATTINGER, Christof

IPC: G01N21/25 ,  G02B3/00 ,  G02B5/04

CPC classification number: G01N21/6452 ,  G01N21/253 ,  G01N2201/024 ,  G02B3/005 ,  G02B3/0068 ,  G02B5/045

Abstract: The invention relates to an imaging system for optical automatic analysers, especially fluorescence readers. On the sample side, the imaging system contains a cylindrical lens array (6) and a prism array (7), which is arranged upstream of the cylindrical lens array. The prismatic effect of the prisms (7a-7c) of the prism array (7) lies in the direction of the cylinder axes of the cylindrical lenses (6a-6c). Together with a telescopic imaging system (8, 11), the inventive imaging system creates a number of parallel cylindrical focussing volumes between the cylindrical lens array (6) and a detector array (10), these focussing volumes being slanted towards the optical axis of the telescopic system in relation to the vertical. The arrangement enables the detection of fluorescence with a large aperture in one direction, and at the same time enables depth selective analysis of the fluorescence signal, especially the discrimination of the fluorescent radiation originating from the areas around the bases of the sample containers from the fluorescent radiation originating from the solution above. With the focussing volumes that are slanted towards the bases of the sample containers, the imaging system ensures that the fluorescence from the areas around the bases of the sample containers (5a-5c) is detected with the same sensitivity even when the heights of the bases vary in the individual sample containers.

公开(公告)号：EP1482298A1

公开(公告)日：2004-12-01

申请号：EP03405378.5

申请日：2003-05-26

Applicant: Sensorix

Inventor： Rothmaier, Markus ,  Busse-Grawitz, Max Erick ,  Schmidiger, Thomas

IPC: G01N21/25 ,  G01J3/02 ,  G01N21/77

CPC classification number: G01N21/4738 ,  G01J3/02 ,  G01J3/0216 ,  G01J3/10 ,  G01N21/645 ,  G01N21/78 ,  G01N2201/024

Abstract: The invention relates to an arrangement for continuous determination of a substance comprising a chemically reacting sensor element (21) arranged in or adjacent to a limiting wall of a volume (22) containing the substance, where in a housing (2) of a modular device (1) optical elements to read the sensor element (21) are arranged, comprising at least one light source (35) illuminating the sensor element (21) and at least one sample detector (29) detecting the light scattered by the sensor element (21), and where a front side of the housing (2) comprises a coupling for the sensor element (21) is arranged, so that the sensor element (21) may be interchangeably and modularly coupled to the front side of the housing (2). A glass body (24) is arranged adjacent to the coupling for direct contact with the sensor element (21) and separate conduits (34, 31) for the illuminating and for the scattered light are arranged rearward of the glass body (24). The modular device (1) allows for easily interchanging the modular sensor element (21) and provides an optical connection between the sensor element (21) and the detector (29) which is steady and allows for high quality measurements.

Abstract translation: 用于连续确定物质的模块化感测装置包括布置在容纳该物质的容积（22）的限制壁中或邻近其的邻近的化学反应传感器元件（21）。 玻璃体（24）被布置成与耦合件相邻，用于与传感器元件直接接触，并且用于照明和用于散射光的分离的导管（31,34）布置在玻璃体的后方。 用于连续确定物质的模块化感测装置包括布置在包含该物质的容积的限制壁中或邻近的化学反应传感器元件。 在模块化装置（1）的壳体（2）中，布置了用于读取传感器元件的光学元件，包括照射传感器元件的至少一个光源（35）和至少一个检测光散射的样本检测器（29） 由传感器元件。 壳体的前侧包括用于传感器元件的联接器，使得传感器元件可以可互换地并且模块地联接到壳体的前侧。 玻璃体被布置在与传感器元件直接接触的联接件附近，并且用于照明和散射光的分开的导管布置在玻璃体的后方。

公开(公告)号：EP1451573A1

公开(公告)日：2004-09-01

申请号：EP02796892.4

申请日：2002-12-03

Applicant: Adiv Association ,  Ofival - Office National Interprofessionnel des Viandes de l'Elevage et de l'Aviculture ,  Interbev - Association Nationale Interprofessionelle du Betail et des Viandes

Inventor： FRENCIA, Jean-Pierre ,  DUFOUR, Eric

IPC: G01N33/02 ,  G01N21/64

CPC classification number: G01N21/6486 ,  G01N33/02 ,  G01N33/12 ,  G01N2021/6484 ,  G01N2201/0221 ,  G01N2201/024

Abstract: The invention concerns a method characterized in that it consists in front fluorescence spectroscopy measurement, said measurement being non-invasive and based on a light source projected on a specific meat zone, measuring the fluorescence spectrum emitted by the fluorophores of said examined zone, said spectrum being addressed in a spectrometer (5) connected to a computer (6) including a system for acquiring and mathematical processing of data, capable of processing said spectrum to deduce therefrom parameters representing the tenderness of the meat or the freshness of the fish, and the light energy exciting the fluorophores is established on a wavelength of 250 to 290 nm corresponding to the fluorophore exciting wavelength and in particular protein tryptophans, aromatic amino acids and nucleic acids.

公开(公告)号：EP1386139A2

公开(公告)日：2004-02-04

申请号：EP02724136.3

申请日：2002-05-07

Applicant: Deutsches KrebsforschungszentrumStiftung des öffentlichen Rechts

Inventor： LANGOWSKI, Jörg ,  WACHSMUTH, Malte

IPC: G01N21/64 ,  G01N25/58 ,  G02B21/00

CPC classification number: G01N21/6458 ,  G01N2201/024 ,  G02B21/002

Abstract: A fluorescence fluctuation microscope, in which excitation light and detection light are coupled into or out of a microscope by means of a common beam path, comprises a closed loop scanning unit (22, 23).

公开(公告)号：EP1384987A2

公开(公告)日：2004-01-28

申请号：EP03021981.0

申请日：1998-10-12

Applicant: CARL ZEISS ,  Carl-Zeiss-Stiftung, trading as Carl Zeiss

Inventor： Völcker, Martin ,  Liegel, Jürgen ,  Gluch, Martin

IPC: G01N21/25 ,  G02B21/00 ,  B01L3/00

CPC classification number: G01N21/6452 ,  B01L3/5085 ,  B01L2300/0829 ,  G01N21/253 ,  G01N21/6456 ,  G01N2201/024

Abstract: Die Erfindung betrifft einen Reader für Mikrotiterplatten (1) und Substanzchips und enthält ein optisches System mit einem Linsenarray (2i, 7) und einem Teleskop aus normalen Linsen (41, 5, 42). Das Linsenarray ist austauschbar, so dass eine Adaption wahlweise für Absorptions-, Fluoreszenz- oder Lumineszenzmessungen möglich ist. Durch das Linsenarray ist eine Parallelmessung (ca. 100 Kanäle) möglich.

Abstract translation: 光学系统具有透镜阵列（21-23）和场透镜（5），用于将检测器阵列（61-63）上的物体的阵列（11-13）投射。 望远镜（41,42）位于透镜阵列（21-23）和场透镜（5）之间以及场透镜和检测器阵列（61-63）之间。 微透镜阵列位于检测器阵列（6）的前方。 照明灯系统可以集成到光学系统中。 光阑孔径阵列（3）位于透镜阵列（21-23）和场透镜（5）之间。 物体显示为包含正在研究的样品或物质芯片的填充的微量滴定板（1）。 该系统是具有吸收的微滴定板的读取器，荧光包括荧光相关光谱或发光。 分光光度计包含独立声明。