METHOD OF ENZYMATIC DEBRIDEMENT.
    122.
    发明公开
    METHOD OF ENZYMATIC DEBRIDEMENT. 失效
    方法用酶解伤口刷新。

    公开(公告)号:EP0039726A4

    公开(公告)日:1982-09-27

    申请号:EP80902337

    申请日:1980-10-24

    发明人: GALBRAITH WILLIAM

    摘要: A process for isolating an enzyme mixture useful in the treatment of devitalized tissue from crude bromelain. The process comprises the steps of (1) suspending the crude bromelain in a weakly basic buffer, preferably sodium borate buffer, to selectively dissolve the active enzyme mixture; (2) separating the undissolved solids from the solution; and (3) removing small molecules having a molecular weight of 10,000 or less from the solution. The product exhibits 15 to 35 units of protease activity per milligram of protein in the presence of cysteine and from 0.5 to 5 units of collagenase activity per milligram of protein. The enzyme mixture is dissolved in an inert solvent carrier containing at least 60 percent water prior to application to the devitalized tissue.

    METHODS AND COMPOSITIONS ADDRESSING DEPRESSED MOOD

    公开(公告)号:EP3922245A1

    公开(公告)日:2021-12-15

    申请号:EP21186364.2

    申请日:2015-06-12

    发明人: MEYER, Jeffrey H.

    摘要: A method of treating or preventing depressed mood is describe, such as for treating or preventing postpartum blues or depression or other conditions associated with increased MAO-A levels. The method comprises administering to a subject an antioxidant source at least once between day-1 to day-5 postpartum (or on treatment days 1 to 5 of a non-postpartum regimen); an optional tryptophan composition on the evening of day-3 to day-5, simultaneously or following the antioxidant source; and a tyrosine composition the day after administering the tryptophan composition, for example on day-5. Individuals with depressed mood due to perimenopause, smoking cessation, or due to an alcohol use disorder or withdrawal therefrom may benefit from the treatment