公开(公告)号：EP2021475A1

公开(公告)日：2009-02-11

申请号：EP07719770.5

申请日：2007-05-16

申请人： University of Saskatchewan

发明人： GORDON, John R.

IPC分类号： C12N15/19 ,  A61K38/19 ,  C07K14/52 ,  C12N7/01

CPC分类号： C07K14/522 ,  A61K38/00 ,  C07K14/5421

摘要： The present invention provides novel polypeptide sequences, methods for production thereof and uses thereof for novel ELR-CXC chemokine receptor agonists and antagonists.

摘要翻译： 本发明提供了新的多肽序列，其生产方法及其用于新型ELR-CXC趋化因子受体激动剂和拮抗剂的用途。

公开(公告)号：EP1660675B1

公开(公告)日：2008-12-31

申请号：EP04761572.9

申请日：2004-07-20

申请人： UNIVERSITY OF SASKATCHEWAN

发明人： Schmutz, Sheila Marie ,  Goodall, Julie Janine

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6888 ,  C12Q2600/156

摘要： A single nucleotide polymorphism (SNP) in exon 2 of the cattle IGF2 gene is associated in cattle with phenotypes of increased rib eye area, decreased fat content, decreased marbling, and decreased birth weight. The presence of a C residue at position 150 of SEQ ID NO: 1, results in increased rib eye area, decreased fat content, and decreased marbling. Expression of the IGF2 gene is also affected by genomic imprinting, with the maternally derived IGF2 allele being suppressed during gestation. As a result, an offspring that obtains a paternal IGF2 allele with a C residue at position 150 of SEQ ID NO: 1 will display a phenotype of reduced birth weight as compared to offspring with a paternally derived IGF2 allele with a T residue at this position.

公开(公告)号：EP1282361B1

公开(公告)日：2006-09-27

申请号：EP01933505.8

申请日：2001-05-14

申请人： University of Saskatchewan Technologies Inc.

发明人： MAENZ, David, D. Univ.of Saskatchewan Tech.Inc. ,  NEWKIRK, Rex, W. Univ. of Saskatchewan Tech.Inc. ,  CLASSEN, Henry, L. Univ.of Saskatchewan Tech.Inc ,  TYLER, Robert, T. Univ.of Saskatchewan Tech.Inc.

IPC分类号： A23J1/14 ,  A23K1/14 ,  A23K1/18 ,  A23J3/14 ,  A23L1/211

CPC分类号： C12Y301/03026 ,  A23J1/148 ,  A23J3/14 ,  A23K10/30 ,  A23K20/147 ,  A23K50/00 ,  A23K50/10 ,  A23L11/33

摘要： The present invention relates to a process for the aqueous extraction, fractionation and enzymatic treatment of oilseed materials to generate valued products with no significant low value by-product or waste streams. In particular, the fractionation scheme generates a protein-fibre feed ingredient principally for use with ruminant animals and a second dephytinized high protein fraction. The dephytinized high protein fraction has value as feed ingredient for a variety of species of animals.

公开(公告)号：EP1281760B9

公开(公告)日：2005-12-28

申请号：EP02017134.4

申请日：1998-10-01

申请人： MERIAL ,  The Queen's University of Belfast ,  The University of Saskatchewan

发明人： Allan, Gordon ,  Meehan, Brian ,  Clark, Edward ,  Ellis, John ,  Haines, Deborah ,  Hassard, Lori ,  Harding, John ,  Charreyre, Catherine Elisabeth ,  Chappuis, Gilles Emile ,  Mc Neilly, Francis

IPC分类号： C12N15/34 ,  C07K14/01 ,  A61K39/12 ,  A61K48/00 ,  C12Q1/68 ,  C07K16/08 ,  G01N33/53

CPC分类号： C07K14/005 ,  A23C19/0321 ,  A23C19/0323 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  C12N2750/10021 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043

公开(公告)号：EP0920510B1

公开(公告)日：2005-07-27

申请号：EP97935395.0

申请日：1997-08-08

申请人： University of Saskatchewan

发明人： POTTER, Andrew, A. ,  MANNS, John, G.

IPC分类号： C12N15/16 ,  C12N15/31 ,  C12N15/62 ,  C12N1/21 ,  C07K14/285 ,  C07K7/23 ,  A61K38/09 ,  A61K39/385

CPC分类号： A61K39/0006 ,  A61K39/00 ,  A61K47/62 ,  A61K47/646 ,  A61K47/6829 ,  A61K47/6833 ,  A61K2039/6037 ,  C07K5/1008 ,  C07K5/1019 ,  C07K5/1021 ,  C07K5/1024 ,  C07K7/23 ,  C07K14/005 ,  C07K14/285 ,  C07K14/655 ,  C07K16/26 ,  C07K2319/00 ,  C12N2720/12322

摘要： New immunological carrier systems, DNA encoding the same, and the use of these systems, are disclosed. The carrier systems include chimeric proteins which include a leukotoxin polypeptide fused to one or more selected GnRH multimers which comprise at least one repeating GnRH decapeptide sequence, or at least one repeating unit of a sequence corresponding to at least one epitope of a selected GnRH molecule. Under the invention, the selected GnRH sequences may all be the same, or may correspond to different derivatives, analogues, variants or epitopes of GnRH so long as the GnRH sequences are capable of eliciting an immune response. The leukotoxin functions to increase the immunogenicity of the GnRH multimers fused thereto.

公开(公告)号：EP1382610A3

公开(公告)日：2004-09-15

申请号：EP03023704.4

申请日：1998-12-16

申请人： The University of Saskatchewan

发明人： Aich, Palok, Dept. of Biochemistry ,  Lee, Jeremey S., Dept. of Biochemistry

IPC分类号： C07H21/00 ,  C12Q1/68 ,  C07K16/00

CPC分类号： G11C13/0019 ,  B82Y10/00 ,  C07H21/00 ,  C07K16/44 ,  C12Q1/6825 ,  G11C13/0014 ,  H01L51/0077 ,  H01L51/0093 ,  H01L51/0595 ,  C12Q2563/113 ,  C12Q2563/107 ,  C12Q2527/125

摘要： The invention provides conductive polymers comprising metal-containing nucleic acid duplexes electrically coupled to an electron source. Methods for making conductive metal-containing nucleic acid duplexes are provided, comprising subjecting a nucleic acid duplex to basic conditions in the presence of a divalent metal cation. Methods of using conductive metal-containing nucleic acid duplexes are provided, including methods of genomic analysis, methods of molecular screening and immunological methods that produce antibodies to such molecules.

摘要翻译： 本发明提供了导电聚合物，其包含电耦合到电子源的含金属的核酸双链体。 提供了制备含导电金属的核酸双链体的方法，包括在二价金属阳离子存在下使核酸双链体进行碱性条件。 提供了使用含导电金属的核酸双链体的方法，包括基因组分析方法，分子筛选方法和产生针对这种分子的抗体的免疫学方法。

公开(公告)号：EP1414976A1

公开(公告)日：2004-05-06

申请号：EP02753967.5

申请日：2002-07-10

申请人： University of Saskatchewan

发明人： HUCL, Pierre

IPC分类号： C12N15/60 ,  C12N15/82 ,  C12N9/88 ,  C12N5/10 ,  A01H5/00 ,  A01H5/10

CPC分类号： C12N9/1022 ,  C12N9/88 ,  C12N15/8278

摘要： The present invention is directed to wheat plants having increased resistance to an imidazolinone herbicide. More particularly, the present invention includes wheat plants containing one or more IMI nucleic acids such as an Einkorn IMI cultivar. The present invention also includes seeds produced by these wheat plants and methods of controlling weeds in the vicinity of these wheat plants.

公开(公告)号：EP1292327A2

公开(公告)日：2003-03-19

申请号：EP01944804.2

申请日：2001-06-11

申请人： UNIVERSITY OF SASKATCHEWAN

发明人： POTTER, Andrew, A. ,  BOLTON, Alexandra, J. ,  SONG, Xin, Ming

IPC分类号： A61K39/09 ,  A61K48/00

CPC分类号： C07K14/315 ,  A61K39/00

摘要： The Mig protein gene of Streptococcus dysgalactiae, and the corresponding amino acid sequence, is described, as is the use of the Mig protein in vaccine compositions to prevent and treat bacterial infections in general, and mastitis in particular.

公开(公告)号：EP1246920A2

公开(公告)日：2002-10-09

申请号：EP00960628.6

申请日：2000-08-28

申请人： MERIAL ,  University of Saskatchewan ,  The Queen's University of Belfast

发明人： ELLIS, John Albert ,  ALLAN, Gordon, Moore ,  MEEHAN, Brian ,  CLARK, Edward ,  HAINES, Deborah ,  HASSARD, Lori ,  HARDING, John ,  CHARREYRE, Catherine, Elisabeth ,  CHAPPUIS, Gilles, Emile ,  KRAKOWKA, George, Steve ,  AUDONNET, Jean-Christophe, Francis ,  MCNEILLY, Francis

IPC分类号： C12N15/34 ,  C07K14/01 ,  A61K39/12 ,  C12N7/00

CPC分类号： C07K14/005 ,  A61K2039/53 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/24043 ,  C12N2750/10022

摘要： Porcine circovirus-2 (PCV-2) is a recently identified agent wherein the potential spectrum of PCV-2-associated disease has been expanded by evidence of vertical and sexual transmission and associated reproductive failure in swine populations. PCV-2 was isolated from a litter of aborted piglets from a farm experiencing late term abortions and stillbirths. Severe, diffuse myocarditis was present in one piglet associated with extensive immunohistochemical staining for PCV-2 antigen. Variable amounts of PCV-2 antigen were also present in liver, lung and kidney of multiple fetuses. Inoculation of female pigs with a composition including an immunogen from PCV-2 or an epitope of interest from such an immunogen or with a vector expressing such an immunogen or epitope of interest prior to breeding, such as within the first five weeks of life, or prior to the perinatal period, or repeatedly over a lifetime, or during pregnancy, such as between the 6th and 8th and/or the 10th and 13th weeks of gestation, can prevent myocarditis, abortion and intrauterine infection associated with porcine circovirus-2. In addition, innoculation of male and/or female pigs with the aforementioned compositions can be carried out to prevent transmission of PCV-2 from male to female (or vice versa) during mating. Thus, the invention involves methods and compositions for preventing myocarditis, abortion and intrauterine infection associated with porcine circovirus-2.

公开(公告)号：EP1159426A1

公开(公告)日：2001-12-05

申请号：EP00908866.7

申请日：2000-03-10

申请人： The University of Saskatchewan

发明人： POTTER, Andrew, A. ,  RIOUX, Clement ,  SCHRYVERS, Anthony, B.

IPC分类号： C12N15/31 ,  C07K14/285 ,  A61K39/102 ,  G01N33/68

CPC分类号： C07K14/285 ,  A61K39/00

摘要： Cloning and expression of genes encoding H. somnus transferring-binding proteins are described. The transferrin-binding proteins can be used in vaccine compositions for the prevention and treatment of H. somnus infections, as well as in diagnostic methods for determining the presence of H. Somnus infections.